Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[(2aS,8R,8aR)-3-(4-fluorobenzoyl)-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylamino]-4-oxobutanoic acid
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 PubChem ID
CID: 145966642
Canonical SMILES
OC(=O)CCC(=O)N(C1CC1)[C@@H]1[C@@H]2CC[C@@H]2N(C(=O)c2ccc(F)cc2)c2ccccc12
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Compound Formula C25H25FN2O4
Compound Structure
Protein Name
 Protein Info 
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
Ki = 7.3 nM
   TI
   LI
   LO
   TS