Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
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 PubChem ID
CID: 11508736
SID: 16610671
Canonical SMILES
Cc1c(CC(O)=O)c2cccnc2n1Cc1ccc(cc1)S(C)(=O)=O
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Compound Formula C18H18N2O4S
Compound Structure
Protein Name
 Protein Info 
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
2
Kd = 15.14 nM
   TI
   LI
   LO
   TS
3
Ki = 36 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
Ki = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM
2 IC50 = 4 nM
3 IC50 = 5 nM
4 IC50 = 31 nM
5 IC50 = 102 nM
6 IC50 > 10000 nM