Brief Information of the Compound and Protein
Compound Name
2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid
    Show/Hide
PubChem ID
CID: 11462174
SID: 16562039
Canonical SMILES
Cc1c(Cc2ccc3ccccc3n2)c2cc(F)ccc2n1CC(O)=O
    Show/Hide
Compound Formula C21H17FN2O2
Compound Structure
Protein Name
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM
2 IC50 = 44 nM
3 IC50 = 100 nM