Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT04730 , Histamine H4 receptor
 Protein Info 
Gene Name HRH4
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID Q91ZY2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT04730
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0487568
 Compound Info 
N-(2,2-dimethylpropyl)-4-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)pyrimidin-2-amine
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C15H22N6
  2
1
EC50 = 12.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 1.23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0487580
 Compound Info 
4-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-N-(2,2-dimethylpropyl)pyrimidin-2-amine
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C15H27N5
  2
1
EC50 = 50.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 30.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423668
 Compound Info 
N-(2,2-dimethylpropyl)-4-[(3R)-3-[methyl(tritritiomethyl)amino]pyrrolidin-1-yl]pyrimidin-2-amine;2,2,2-trifluoroacetic acid
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C19H29F6N5O4
  1
1
EC50 = 199.53 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0041262
 Compound Info 
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
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C14H16ClN3O
  2
1
Ki = 3.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 11.75 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0482310
 Compound Info 
(E)-but-2-enedioic acid;4-[3-(propylamino)azetidin-1-yl]pyrimidin-2-amine;hydrate
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C14H23N5O5
  1
1
Ki = 15.85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0220828
 Compound Info 
4-N-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine
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C13H22N6
  1
1
Ki = 20.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0044460
 Compound Info 
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
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C15H24N4S
  1
1
Ki = 66.07 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0041493
 Compound Info 
Clobenpropit
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C14H17ClN4S
  1
1
Ki = 123.03 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0823737
 Compound Info 
SID50106398
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C5H11Cl2N3
  1
1
Ki = 2137.96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS