Brief Information of the Compound and Protein
Compound Name
N-(2,2-dimethylpropyl)-4-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)pyrimidin-2-amine
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PubChem ID
CID: 155524115
Canonical SMILES
CC(C)(C)CNc1nccc(n1)N1CCc2nc[nH]c2C1
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Compound Formula C15H22N6
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY2
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
EC50 = 12.59 nM
   TI
   LI
   LO
   TS
2
Ki = 1.23 nM
   TI
   LI
   LO
   TS