Compound ID |
Compound Name |
Compound Formula |
CP0042711
|
4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
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|
C18H20O2
|
1
|
1 |
EC50 = 0.02 nM
|
|
|
CP0006292
|
(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol
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|
C18H24O2
|
5
|
1 |
EC50 = 0.07 nM
|
|
|
2 |
EC50 = 0.37 nM
|
|
|
3 |
EC50 = 0.59 nM
|
|
|
4 |
EC50 = 0.84 nM
|
|
|
5 |
IC50 = 24 nM
|
|
|
CP0044042
|
(1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one
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|
C18H22O2
|
3
|
1 |
EC50 = 2.1 nM
|
|
|
2 |
EC50 = 26 nM
|
|
|
3 |
EC50 = 166 nM
|
|
|
CP0012708
|
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
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|
C15H10O5
|
3
|
1 |
EC50 = 4.1 nM
|
|
|
2 |
EC50 = 73 nM
|
|
|
3 |
EC50 = 956 nM
|
|
|
CP0063761
|
(1S,10R,11S,14R,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol
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|
C18H24O2
|
1
|
1 |
EC50 = 4.5 nM
|
|
|
CP0342151
|
3-arylquinazolinethione, 1ba
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|
C14H10N2O3S
|
2
|
1 |
EC50 = 13 nM
|
|
|
2 |
EC50 = 2793 nM
|
|
|
CP0053327
|
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromene-4-thione
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|
C15H10O4S
|
2
|
1 |
EC50 = 14 nM
|
|
|
2 |
EC50 = 1125 nM
|
|
|
CP0214394
|
2-(4-hydroxy-2-methylphenyl)-1-benzothiophen-6-ol
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|
C15H12O2S
|
1
|
1 |
EC50 = 15 nM
|
|
|
CP0141053
|
2-(4-hydroxyphenyl)-1-benzothiophen-6-ol
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|
C14H10O2S
|
1
|
1 |
EC50 = 17 nM
|
|
|
CP0074985
|
3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazoline-4-thione
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|
C14H9FN2O3S
|
2
|
1 |
EC50 = 20 nM
|
|
|
2 |
EC50 = 776 nM
|
|
|
CP0334570
|
2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophen-6-ol
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|
C14H9FO2S
|
1
|
1 |
EC50 = 32 nM
|
|
|
CP0154961
|
3-arylquinazolinethione, 1be
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|
C16H14N2O2S
|
2
|
1 |
EC50 = 53 nM
|
|
|
2 |
EC50 = 1462 nM
|
|
|
CP0274861
|
3-arylquinazolinone, 1aan
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|
C16H14N2O3
|
2
|
1 |
EC50 = 62 nM
|
|
|
2 |
EC50 = 4521 nM
|
|
|
CP0095067
|
3-arylquinazolinone, 1aa
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|
C14H10N2O4
|
2
|
1 |
EC50 = 76 nM
|
|
|
2 |
EC50 = 2918 nM
|
|
|
CP0162129
|
3-arylquinazolinone, 1ac
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|
C15H12N2O4
|
2
|
1 |
EC50 = 111 nM
|
|
|
2 |
EC50 = 5305 nM
|
|
|
CP0167082
|
3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one
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|
C14H9FN2O4
|
2
|
1 |
EC50 = 117 nM
|
|
|
2 |
EC50 = 3112 nM
|
|
|
CP0222463
|
3-arylquinazolinone, 1aaj
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|
C15H12N2O3
|
2
|
1 |
EC50 = 136 nM
|
|
|
2 |
EC50 = 2392 nM
|
|
|
CP0109776
|
3-arylquinazolinethione, 1bc
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|
C15H12N2O3S
|
2
|
1 |
EC50 = 160 nM
|
|
|
2 |
EC50 = 2406 nM
|
|
|
CP0228049
|
2-phenyl-1-benzothiophen-6-ol
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|
C14H10OS
|
1
|
1 |
EC50 = 166 nM
|
|
|
CP0276781
|
3-arylquinazolinethione, 1bf
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|
C13H9N3O3S
|
2
|
1 |
EC50 = 173 nM
|
|
|
2 |
EC50 = 4859 nM
|
|
|
CP0185029
|
2-(4-methylphenyl)-1-benzothiophen-6-ol
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|
C15H12OS
|
1
|
1 |
EC50 = 174 nM
|
|
|
CP0148181
|
2-(4-hydroxy-3-propylphenyl)-1-benzothiophen-6-ol
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|
C17H16O2S
|
1
|
1 |
EC50 = 186 nM
|
|
|
CP0133181
|
3-(2-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one
Show/Hide
|
C14H9FN2O4
|
2
|
1 |
EC50 = 190 nM
|
|
|
2 |
EC50 = 1143 nM
|
|
|
CP0109775
|
3-arylquinazolinethione, 1bd
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|
C15H12N2O2S
|
2
|
1 |
EC50 = 222 nM
|
|
|
2 |
EC50 = 1669 nM
|
|
|
CP0040010
|
2-(3-hydroxyphenyl)-1-benzothiophen-6-ol
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|
C14H10O2S
|
1
|
1 |
EC50 = 245 nM
|
|
|
CP0205233
|
3-(2-chloro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one
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|
C14H9ClN2O4
|
2
|
1 |
EC50 = 251 nM
|
|
|
2 |
EC50 = 1427 nM
|
|
|
CP0210429
|
2-(3-ethyl-4-hydroxyphenyl)-1-benzothiophen-6-ol
Show/Hide
|
C16H14O2S
|
1
|
1 |
EC50 = 257 nM
|
|
|
CP0203623
|
2-(4-hydroxy-3-methylphenyl)-1-benzothiophen-6-ol
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|
C15H12O2S
|
1
|
1 |
EC50 = 302 nM
|
|
|
CP0205232
|
3-arylquinazolinone, 1ak
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|
C13H9N3O4
|
2
|
1 |
EC50 = 358 nM
|
|
|
2 |
EC50 = 3143 nM
|
|
|
CP0203601
|
4-(6-hydroxy-1-benzothiophen-2-yl)benzene-1,2-diol
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|
C14H10O3S
|
1
|
1 |
EC50 = 525 nM
|
|
|
CP0146459
|
3-arylquinazolinone, 1am
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|
C14H9IN2O4
|
2
|
1 |
EC50 = 593 nM
|
|
|
2 |
EC50 = 8317 nM
|
|
|
CP0167085
|
3-arylquinazolinone, 1aas
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|
C17H14N2O3
|
2
|
1 |
EC50 = 729 nM
|
|
|
2 |
EC50 = 4261 nM
|
|
|
CP0283226
|
3-arylquinazolinone, 1aao
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|
C16H12N2O3
|
2
|
1 |
EC50 = 750 nM
|
|
|
2 |
EC50 = 4624 nM
|
|
|
CP0070388
|
Bisphenol A (BPA)
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|
C15H16O2
|
1
|
1 |
EC50 = 757 nM
|
|
|
CP0222461
|
3-arylquinazolinone, 1at
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|
C14H10N2O4
|
2
|
1 |
EC50 = 904 nM
|
|
|
2 |
EC50 = 10082 nM
|
|
|
CP0141380
|
3-arylquinazolinone, 1as
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|
C14H10N2O3
|
1
|
1 |
EC50 = 961 nM
|
|
|
CP0179273
|
3-arylquinazolinone, 1aac
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|
C14H10N2O4S
|
2
|
1 |
EC50 = 983 nM
|
|
|
2 |
EC50 = 1985 nM
|
|
|
CP0045464
|
3-(3-chloro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one
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|
C14H9ClN2O4
|
2
|
1 |
EC50 = 1181 nM
|
|
|
2 |
EC50 = 5137 nM
|
|
|
CP0316541
|
3-arylquinazolinone, 1ai
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|
C15H12N2O4
|
2
|
1 |
EC50 = 1254 nM
|
|
|
2 |
EC50 = 4576 nM
|
|
|
CP0167098
|
2-ethyl-5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one
Show/Hide
|
C16H14N2O4
|
2
|
1 |
EC50 = 1261 nM
|
|
|
2 |
EC50 = 9317 nM
|
|
|
CP0141377
|
2,5,7-trihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one
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|
C14H10N2O5
|
2
|
1 |
EC50 = 1313 nM
|
|
|
2 |
EC50 = 9268 nM
|
|
|
CP0420367
|
CHEBI:34029
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|
C14H14O2
|
1
|
1 |
EC50 = 1395 nM
|
|
|
CP0288405
|
3-arylquinazolinone, 1av
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|
C15H12N2O4
|
1
|
1 |
EC50 = 1583 nM
|
|
|
CP0320563
|
3-arylquinazolinone, 1ap
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|
C14H9IN2O4
|
1
|
1 |
EC50 = 1638 nM
|
|
|
CP0283224
|
3-arylquinazolinone, 1au
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|
C14H10N2O3
|
1
|
1 |
EC50 = 1721 nM
|
|
|
CP0109772
|
3-arylquinazolinone, 1an
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|
C14H8I2N2O4
|
1
|
1 |
EC50 = 1966 nM
|
|
|
CP0179292
|
3-arylquinazolinone, 1aai
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|
C14H11N3O3
|
1
|
1 |
EC50 = 2064 nM
|
|
|
CP0274862
|
3-arylquinazolinone, 1aam
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|
C15H9F3N2O6S
|
1
|
1 |
EC50 = 3804 nM
|
|
|
CP0140876
|
3-arylquinazolinone, 1aab
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|
C15H12N2O4S
|
1
|
1 |
EC50 = 3843 nM
|
|
|
CP0167086
|
3-arylquinazolinone, 1aar
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|
C15H12N2O4
|
1
|
1 |
EC50 = 4457 nM
|
|
|
CP0236221
|
3-arylquinazolinone, 1aal
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|
C15H9N3O3
|
1
|
1 |
EC50 = 7579 nM
|
|
|
CP0161944
|
3-arylquinazolinone, 1ab
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|
C15H12N2O4
|
1
|
1 |
EC50 = 8506 nM
|
|
|
CP0334411
|
3-arylquinazolinone, 1aak
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|
C15H12N2O4
|
1
|
1 |
EC50 = 8506 nM
|
|
|
CP0044826
|
2-chloro-5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one
Show/Hide
|
C14H9ClN2O4
|
1
|
1 |
EC50 = 8776 nM
|
|
|
CP0205163
|
3-arylquinazolinone, 1ao
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|
C15H12N2O4
|
2
|
1 |
EC50 = 8870 nM
|
|
|
2 |
EC50 = 9344 nM
|
|
|
CP0276123
|
3-arylquinazolinone, 1aap
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|
C16H12N2O5
|
1
|
1 |
EC50 = 9406 nM
|
|
|
CP0045448
|
3-arylquinazolinone, 1al
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|
C13H9N3O4
|
1
|
1 |
EC50 = 9763 nM
|
|
|
CP0807075
|
methyl 7-acetoxy-3-(4-acetoxyphenyl)-4-thioxo-3,4-dihydroquinazoline-5-carboxylate
Show/Hide
|
C20H16N2O6S
|
1
|
1 |
EC50 = 11342 nM
|
|
|
CP0211271
|
3-arylquinazolinone, 1aaq
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|
C20H14N2O3
|
1
|
1 |
EC50 = 11685 nM
|
|
|
CP0178147
|
1-[2-hydroxy-5-(6-hydroxy-1-benzothiophen-2-yl)phenyl]ethan-1-one
Show/Hide
|
C16H12O3S
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0214393
|
2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophene-4,6-diol
Show/Hide
|
C14H9FO3S
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0257596
|
2-(4-hydroxy-3-methylphenyl)-1-benzothiophene-4,6-diol
Show/Hide
|
C15H12O3S
|
1
|
1 |
EC50 > 1000 nM
|
|
|
CP0040732
|
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C28H31NO2
|
2
|
1 |
IC50 = 13 nM
|
|
|
2 |
IC50 = 24 nM
|
|
|
CP0409283
|
4-[2,2,2-tribromo-1-(4-hydroxyphenyl)ethyl]phenol
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|
C14H11Br3O2
|
2
|
1 |
IC50 = 40.2 nM
|
|
|
2 |
Kd = 4.677 nM
|
|
|
CP0059607
|
CHEBI:72754
Show/Hide
|
C15H10F6O2
|
2
|
1 |
IC50 = 69.8 nM
|
|
|
2 |
Kd = 10.72 nM
|
|
|
CP0414384
|
4-[2,2,2-trichloro-1-(4-hydroxyphenyl)ethyl]phenol
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|
C14H11Cl3O2
|
2
|
1 |
IC50 = 85.4 nM
|
|
|
2 |
Kd = 11.22 nM
|
|
|
CP0486016
|
1-(4-{octahydro-1H-pyrido[1,2-a]piperazin-2-yl}phenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
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|
C29H33N3O
|
2
|
1 |
IC50 = 98 nM
|
|
|
2 |
IC50 = 252 nM
|
|
|
CP0428331
|
1-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
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|
C27H31N3O
|
2
|
1 |
IC50 = 106 nM
|
|
|
2 |
IC50 = 330 nM
|
|
|
CP0503858
|
2-(4-fluorophenyl)-1-[4-(1-methylpiperidin-4-yl)phenyl]-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C27H29FN2O
|
2
|
1 |
IC50 = 162 nM
|
|
|
2 |
IC50 = 239 nM
|
|
|
CP0391567
|
1-[4-(4-ethyl-3-methylpiperazin-1-yl)phenyl]-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C28H33N3O
|
2
|
1 |
IC50 = 173 nM
|
|
|
2 |
IC50 = 399 nM
|
|
|
CP0441762
|
1-[4-(4-methylpiperazin-1-yl)phenyl]-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C26H29N3O
|
2
|
1 |
IC50 = 180 nM
|
|
|
2 |
IC50 = 428 nM
|
|
|
CP0041761
|
2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol
Show/Hide
|
C28H27NO4S
|
2
|
1 |
IC50 = 260 nM
|
|
|
2 |
IC50 = 341 nM
|
|
|
CP0428333
|
1-[4-(1-methylpiperidin-4-yl)phenyl]-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C27H30N2O
|
2
|
1 |
IC50 = 266 nM
|
|
|
2 |
IC50 = 464 nM
|
|
|
CP0378036
|
1-[4-(4-cyclopentylpiperazin-1-yl)phenyl]-2-(3-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C30H35N3O2
|
2
|
1 |
IC50 = 268 nM
|
|
|
2 |
IC50 = 1110 nM
|
|
|
CP0421247
|
1-[4-(4-cyclohexylpiperazin-1-yl)phenyl]-2-(3-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C31H37N3O2
|
2
|
1 |
IC50 = 276 nM
|
|
|
2 |
IC50 = 1285 nM
|
|
|
CP0496081
|
2-(3-hydroxyphenyl)-1-{4-[4-(propan-2-yl)piperazin-1-yl]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C28H33N3O2
|
2
|
1 |
IC50 = 286 nM
|
|
|
2 |
IC50 = 943 nM
|
|
|
CP0428338
|
2-(3-hydroxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C26H29N3O2
|
2
|
1 |
IC50 = 287 nM
|
|
|
2 |
IC50 = 1677 nM
|
|
|
CP0050678
|
2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C28H32N2O2
|
2
|
1 |
IC50 = 289 nM
|
|
|
2 |
IC50 = 346 nM
|
|
|
CP0420366
|
4-[2,2,2-trifluoro-1-(4-hydroxyphenyl)ethyl]phenol
Show/Hide
|
C14H11F3O2
|
2
|
1 |
IC50 = 331 nM
|
|
|
2 |
Kd = 42.66 nM
|
|
|
CP0144749
|
1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C21H18FNO
|
1
|
1 |
IC50 = 421 nM
|
|
|
CP0421365
|
2-(3-hydroxyphenyl)-1-{4-[4-(2-methylpropyl)piperazin-1-yl]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C29H35N3O2
|
2
|
1 |
IC50 = 491 nM
|
|
|
2 |
IC50 = 1945 nM
|
|
|
CP0391060
|
2-(3-hydroxyphenyl)-1-[4-(1-methylpiperidin-4-yl)phenyl]-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C27H30N2O2
|
2
|
1 |
IC50 = 496 nM
|
|
|
2 |
IC50 = 1730 nM
|
|
|
CP0503859
|
2-(3-fluorophenyl)-1-[4-(1-methylpiperidin-4-yl)phenyl]-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C27H29FN2O
|
2
|
1 |
IC50 = 879 nM
|
|
|
2 |
IC50 > 1000 nM
|
|
|
CP0498205
|
1-[4-(3-ethyl-4-methylpiperazin-1-yl)phenyl]-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C28H33N3O
|
2
|
1 |
IC50 = 1155 nM
|
|
|
2 |
IC50 = 4454 nM
|
|
|
CP0404806
|
1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl}-2-(3-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C29H33N3O2
|
1
|
1 |
IC50 = 1370 nM
|
|
|
CP0003923
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(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine
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C26H29NO
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2
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1 |
IC50 = 1530 nM
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2 |
IC50 > 1000 nM
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