Brief Information of the Compound and Protein
Compound Name
1-(4-{octahydro-1H-pyrido[1,2-a]piperazin-2-yl}phenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol
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PubChem ID
CID: 11430588
SID: 16527987
Canonical SMILES
Oc1ccc2C(N(CCc2c1)c1ccccc1)c1ccc(cc1)N1CCN2CCCCC2C1
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Compound Formula C29H33N3O
Compound Structure
Protein Name
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
2
IC50 = 252 nM
   TI
   LI
   LO
   TS