Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one
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 PubChem ID
CID: 5870
SID: 49684201
Canonical SMILES
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O
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Compound Formula C18H22O2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 2.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 26 nM
   TI
   LI
   LO
   TS
3
EC50 = 166 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.94 nM
2 EC50 = 8 nM
3 EC50 = 1135 nM
4 IC50 = 31 nM
5 IC50 = 540 nM