| Compound ID |
Compound Name |
Compound Formula |
|
CP0067443
|
2-[4-[4-[[5-(3,4-difluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]cyclohexyl]acetic acid
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|
C23H22F2N4O4
|
2
|
| 1 |
IC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0429525
|
(2S)-1-[5-[4-[[3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
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|
C25H21F3N4O4
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0535252
|
(2S)-1-[5-[4-[(3-chlorophenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
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|
C24H21ClN4O4
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0431605
|
2,2-dimethyl-3-[[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]oxy]propanoic acid
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|
C25H24N4O4
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0524993
|
2-[4-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]cyclohexyl]acetic acid
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|
C23H23FN4O4
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0454081
|
(1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid
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|
C27H22F4N2O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0947165
|
4-amino-6-(2'-chloro-4'-methylbiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
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|
C20H17ClN4O2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0424427
|
N-(6-morpholin-4-ylpyridin-3-yl)-5-(3-phenylanilino)-1,3,4-oxadiazole-2-carboxamide
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|
C24H22N6O3
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0454082
|
(1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid
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|
C26H23ClN2O4
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0238531
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]-3-chlorophenyl]acetic acid
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|
C21H18ClN3O3
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0441083
|
N-(6-morpholin-4-ylpyridin-3-yl)-5-(3-phenoxyanilino)-1,3,4-oxadiazole-2-carboxamide
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|
C24H22N6O4
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0542952
|
5-(2-fluoroanilino)-N-(6-phenoxypyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
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|
C20H14FN5O3
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0209945
|
(1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}phenyl)carbonyl]cyclopentane-1-carboxylic acid
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|
C26H24N2O4
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 7.8 nM
|
|
|
|
CP0535411
|
(1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoyl)amino]phenyl}phenyl)carbonyl]cyclopentane-1-carboxylic acid
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|
C27H24N2O6
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0397270
|
4-amino-6-[4-[1-(1,2,5-oxadiazole-3-carbonyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
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|
C21H21N7O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0509242
|
[(2S)-4-methyl-1-[[1-[[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxo-4-phenylbutan-2-yl]carbamoyl]cyclopentyl]amino]-1-oxopentan-2-yl] 2,2-dimethylpropanoate
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|
C31H48N2O6
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0778789
|
4-amino-6-(2'-fluorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
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|
C19H15FN4O2
|
1
|
| 1 |
IC50 = 7.7 nM
|
|
|
|
CP0240421
|
(2S)-2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-fluorophenyl]-3-chlorophenyl]propanoic acid
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|
C22H19ClFN3O3
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0798361
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2,2'-dichlorobiphenyl-4-yl)acetic acid
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|
C21H17Cl2N3O3
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0541342
|
N-(5-benzyl-4-phenyl-1,3-thiazol-2-yl)-4-(4,5-diethoxy-2-methylphenyl)-4-oxobutanamide
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|
C31H32N2O4S
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0558251
|
(2S)-1-[5-[4-[(2-chlorophenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C24H21ClN4O4
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0457753
|
(2S)-1-[5-[4-[(4-chlorophenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C24H21ClN4O4
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0454083
|
(1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid
Show/Hide
|
C27H23F3N2O4
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0528296
|
(1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid
Show/Hide
|
C27H23F3N2O4
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0941276
|
(1R,2R)-2-{[4-({[(4-methoxyphenyl)amino]carbonyl}amino)-1,1-biphenyl-4-yl]carbonyl}cyclopentanecarboxylic acid
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|
C27H25FN2O5
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0455441
|
2-[4-[4-[5-[(5-cyclobutyl-1,3,4-thiadiazol-2-yl)amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C25H28N4O2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0454085
|
(1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid
Show/Hide
|
C27H23F3N2O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0859199
|
4-amino-6-(2'-chloro-2-fluorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H14ClFN4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0949742
|
4-amino-6-(2',4'-dichlorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H14Cl2N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0513574
|
3-[4-[6-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-1H-benzimidazol-2-yl]-3,5-dimethylphenyl]propanoic acid
Show/Hide
|
C27H24N4O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0454084
|
(1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid
Show/Hide
|
C26H23FN2O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0388731
|
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]butanoic acid
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|
C20H18Cl2N4O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0563573
|
[(2S)-1-[[1-[[(1S)-1-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-3-phenylpropyl]carbamoyl]cyclopentyl]amino]-4-methyl-1-oxopentan-2-yl] 2,2-dimethylpropanoate
Show/Hide
|
C31H44N4O5
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0767187
|
(S)-2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-chlorobiphenyl-4-yl)propanoic acid
Show/Hide
|
C22H20ClN3O3
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
|
CP0388732
|
2-[[5-[4-(1-benzothiophene-2-carbonylamino)phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
|
C21H18N4O3S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0441084
|
N-(6-morpholin-4-ylpyridin-3-yl)-5-(3-phenylmethoxyanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C25H24N6O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0513575
|
3-[3,5-dimethyl-4-[6-(quinolin-2-ylcarbamoyl)-1H-benzimidazol-2-yl]phenyl]propanoic acid
Show/Hide
|
C28H24N4O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0037323
|
2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)bicyclo[2.2.2]octan-1-yl]acetic acid
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0037325
|
2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)cyclohexyl]acetic acid
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0894340
|
4-Amino-6-(2'-chlorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H15ClN4O2
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0910408
|
4-amino-6-(2',6'-difluorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H14F2N4O2
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0939769
|
4-amino-6-(2',5'-dichlorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H14Cl2N4O2
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0962038
|
4-amino-6-(2,2',6'-trifluorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H13F3N4O2
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0478112
|
(2S)-1-[5-[4-[(2-methoxyphenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C25H24N4O5
|
1
|
| 1 |
IC50 = 15.9 nM
|
|
|
|
CP0548681
|
N-(4-butylsulfanylphenyl)-5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H19FN4O2S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0244107
|
3-[4-[6-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-1H-benzimidazol-2-yl]-3,5-dimethylphenyl]-2,2-dimethylpropanoic acid
Show/Hide
|
C29H28N4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0475273
|
(2S)-1-[5-[4-[(4-methoxyphenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C25H24N4O5
|
1
|
| 1 |
IC50 = 18.4 nM
|
|
|
|
CP0400124
|
2-[4-[4-[[5-(2-cyclopentylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H31N3O3S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0085747
|
2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H24N4O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0443966
|
2-[4-[4-[(8R)-4-amino-8-methyl-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0721722
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-methylbiphenyl-4-yl)acetic acid
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0883348
|
4-amino-6-(2'-chloro-6'-methylbiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C20H17ClN4O2
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0927888
|
4-amino-6-(2'-chloro-4'-(difluoromethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C20H15ClF2N4O2
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0949740
|
(R)-4-Amino-6-(2'-chloro-4'-(2-(3-hydroxypyrrolidin-1-yl)-2-oxoethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C25H24ClN5O4
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0439981
|
2-[[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
|
C23H20N4O3S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
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CP0389398
|
2-[4-[4-[4-[[4-fluoro-2-(trifluoromethyl)phenyl]carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H28F4N2O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0410016
|
2-[4-[4-[4-[[2-(trifluoromethyl)phenyl]carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H29F3N2O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0485296
|
N-[2-[[1-phenyl-3-(trifluoromethyl)pyrazole-4-carbonyl]amino]ethyl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C21H17F6N5O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
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CP0525528
|
5-(2-fluoroanilino)-N-(6-thiomorpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17FN6O2S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0390734
|
2-[4-[4-(6-amino-5-oxo-2,3-dihydropyrido[3,2-f][1,4]oxazepin-4-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H25N3O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0551651
|
2-[2-(2,6-dichlorophenyl)-3H-benzimidazol-5-yl]-5-(4-methoxyphenyl)-1,3,4-oxadiazole
Show/Hide
|
C22H14Cl2N4O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0488962
|
(2S)-1-[5-[4-(phenylcarbamoylamino)phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C24H22N4O4
|
1
|
| 1 |
IC50 = 23.4 nM
|
|
|
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CP0530183
|
2-[4-[4-[[5-(cyclopentylmethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H29N3O3S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
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CP0488080
|
N-(2-fluorophenyl)-4-[5-[(3,6,7-trimethyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carboxamide
Show/Hide
|
C28H28FN5O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0519371
|
6-Ethoxy-N-[2-({[1-phenyl-3-(trifluoromethyl)-1Hpyrazol-4-yl]carbonyl}amino)ethyl]pyridine-3-carboxamide
Show/Hide
|
C21H20F3N5O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
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CP0544046
|
N-(2-fluorophenyl)-4-[5-[(3-methyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carboxamide
Show/Hide
|
C26H24FN5O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0390736
|
4-amino-6-[4-[4-(2-hydroxy-2-methylpropyl)cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C23H30N4O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0767188
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-fluorobiphenyl-4-yl)acetic acid
Show/Hide
|
C21H18FN3O3
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
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CP0876336
|
4-Amino-6-(2'-chloro-4'-(hydroxymethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C20H17ClN4O3
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0939768
|
2-(4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)acetic acid
Show/Hide
|
C21H17ClN4O4
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
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CP0375927
|
2-[[2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetyl]-methylamino]acetic acid
Show/Hide
|
C24H29N5O5
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0556908
|
1-[[2-(2-adamantyl)acetyl]amino]-N-[(2S)-1-ethoxy-4-phenylbutan-2-yl]cyclopentane-1-carboxamide
Show/Hide
|
C30H44N2O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0194564
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2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)bicyclo[2.2.2]octan-1-yl]propanoic acid
Show/Hide
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C25H30N4O3
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1
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| 1 |
IC50 = 28 nM
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CP0269658
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4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)bicyclo[2.2.2]octane-1-carboxylic acid
Show/Hide
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C23H26N4O3
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1
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| 1 |
IC50 = 28 nM
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CP0462722
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N-[2-[(4-ethoxybenzoyl)amino]ethyl]-1-pyridin-2-yl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
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C21H20F3N5O3
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1
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| 1 |
IC50 = 28 nM
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CP0467488
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N-[4-[5-(3-amino-2,2-dimethyl-3-oxopropoxy)-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
Show/Hide
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C25H25N5O3
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1
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| 1 |
IC50 = 28 nM
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CP0461831
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3-[4-[6-[(3,4-dimethylphenyl)carbamoyl]-1H-benzimidazol-2-yl]-3,5-dimethylphenyl]propanoic acid
Show/Hide
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C27H27N3O3
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1
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| 1 |
IC50 = 28 nM
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CP0489844
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2-[4-[6-[(3,4-dimethylphenyl)carbamoyl]-1H-benzimidazol-2-yl]-3,5-dimethylphenoxy]acetic acid
Show/Hide
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C26H25N3O4
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1
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| 1 |
IC50 = 28 nM
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CP0452163
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N-[4-[5-[3-(dimethylamino)-2,2-dimethyl-3-oxopropoxy]-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
Show/Hide
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C27H29N5O3
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1
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| 1 |
IC50 = 29 nM
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CP0169387
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3-[[1-[5-[(3-phenoxybenzoyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
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C31H29N3O5
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1
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| 1 |
IC50 = 29 nM
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CP0400128
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(2S)-2-[[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)amino]phenyl]benzoyl]amino]-3-methylbutanoic acid
Show/Hide
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C27H26N4O3S
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1
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| 1 |
IC50 = 30 nM
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CP0430761
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2-[4-[4-[[5-[(3-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C24H24FN3O3S
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1
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| 1 |
IC50 = 30 nM
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CP0525067
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CHEMBL2012631
Show/Hide
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C24H24ClN3O3S
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1
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| 1 |
IC50 = 30 nM
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CP0221805
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2-[6-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)spiro[1,2-dihydroindene-3,4'-cyclohexane]-1'-yl]acetic acid
Show/Hide
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C23H27N3O3
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1
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| 1 |
IC50 = 30 nM
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CP0488553
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3,5-dimethyl-6-[4'-(2H-tetrazol-5-ylmethyl)spiro[2,3-dihydroindene-1,1'-cyclohexane]-5-yl]pyrazine-2-carboxamide
Show/Hide
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C23H27N7O
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1
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| 1 |
IC50 = 30 nM
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CP0553441
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2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-chlorophenyl]cyclohexyl]acetic acid
Show/Hide
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C21H24ClN3O3
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1
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| 1 |
IC50 = 30 nM
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CP0475274
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(2S)-1-[5-[4-[[4-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C25H21F3N4O4
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1
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| 1 |
IC50 = 30.3 nM
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CP0197867
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3-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]propanoic acid
Show/Hide
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C22H26N4O4
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1
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| 1 |
IC50 = 31 nM
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CP0876334
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2-(4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)acetamide
Show/Hide
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C21H18ClN5O3
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1
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| 1 |
IC50 = 31.62 nM
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CP0894392
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N-((4'-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)-N-methylmethanesulfonamide
Show/Hide
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C22H22ClN5O4S
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1
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| 1 |
IC50 = 31.62 nM
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CP0913321
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N-((4'-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)methanesulfonamide
Show/Hide
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C21H20ClN5O4S
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1
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| 1 |
IC50 = 31.62 nM
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CP0956787
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4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-6-chlorobiphenyl-2-carbonitrile
Show/Hide
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C20H14ClN5O2
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1
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| 1 |
IC50 = 31.62 nM
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CP0399815
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5-(3-ethoxyanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
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C20H22N6O4
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1
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| 1 |
IC50 = 32 nM
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CP0478905
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2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetamide
Show/Hide
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C21H25N5O3
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1
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| 1 |
IC50 = 32 nM
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CP0389397
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2-[4-[4-[4-(heptylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C30H40N2O4
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1
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| 1 |
IC50 = 32 nM
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CP0547900
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3-[3,5-dimethyl-4-[6-(quinolin-2-ylcarbamoyl)-1H-benzimidazol-2-yl]phenyl]-2,2-dimethylpropanoic acid
Show/Hide
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C30H28N4O3
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1
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| 1 |
IC50 = 32 nM
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CP0407789
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(2S)-1-[5-[4-[(3-methoxyphenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C25H24N4O5
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1
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| 1 |
IC50 = 32.1 nM
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CP0383423
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N-[2-[(4-ethoxybenzoyl)amino]ethyl]-1-phenyl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
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C22H21F3N4O3
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1
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| 1 |
IC50 = 33 nM
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CP0488076
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3-[[1-[5-[(3-methyl-5-phenyl-1-benzothiophene-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
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C34H31N3O4S
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1
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| 1 |
IC50 = 33 nM
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CP0389399
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2-[4-[4-[4-[(2-ethylphenyl)carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C31H34N2O4
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1
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| 1 |
IC50 = 33 nM
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CP0466201
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methyl 2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetate
Show/Hide
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C22H26N4O4
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1
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| 1 |
IC50 = 34 nM
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CP0526638
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(1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid
Show/Hide
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C27H23N3O4
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1
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| 1 |
IC50 = 35 nM
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CP0437778
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4-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]cyclohexane-1-carboxylic acid
Show/Hide
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C22H21FN4O4
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1
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| 1 |
IC50 = 35 nM
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CP0235312
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2-[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C24H25N3O3S
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1
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| 1 |
IC50 = 36 nM
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CP0397267
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4-amino-6-[4-[4-[2-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
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C24H28N6O3
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1
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| 1 |
IC50 = 37 nM
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CP0115631
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2-[4-[4-[1-(phenylcarbamoyl)indol-5-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C29H28N2O3
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1
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| 1 |
IC50 = 37 nM
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CP0429526
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(2S)-1-[5-[4-[(3-fluorophenyl)carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C24H21FN4O4
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1
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| 1 |
IC50 = 37.7 nM
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CP0427505
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2-[[5-[4-[[2-(3,4-dichlorophenyl)acetyl]amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
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C20H18Cl2N4O3S
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1
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| 1 |
IC50 = 38 nM
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CP0137702
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2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid{6-[(2-Methoxyethyl)methylamino]pyridin-3-yl}amide
Show/Hide
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C20H19F3N4O3
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1
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| 1 |
IC50 = 38 nM
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CP0496053
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N-[4-[5-[2,2-dimethyl-3-oxo-3-(propan-2-ylamino)propoxy]-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
Show/Hide
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C28H31N5O3
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1
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| 1 |
IC50 = 39 nM
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CP0443584
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3-[4-[6-[(4-tert-butylphenyl)carbamoyl]-1H-benzimidazol-2-yl]-3,5-dimethylphenyl]propanoic acid
Show/Hide
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C29H31N3O3
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1
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| 1 |
IC50 = 39 nM
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CP0433348
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4-[5-[(5-fluoro-3-methyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]-N-(2-fluorophenyl)piperazine-1-carboxamide
Show/Hide
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C26H23F2N5O3
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1
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| 1 |
IC50 = 39 nM
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CP0866630
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4-Amino-6-(2'-chloro-4'-(methylsulfonylmethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
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C21H19ClN4O4S
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1
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| 1 |
IC50 = 39.81 nM
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CP0913322
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4-amino-6-(2'-methylbiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
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C20H18N4O2
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1
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| 1 |
IC50 = 39.81 nM
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CP0925466
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4-amino-6-(2'-chloro-4'-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
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C24H22ClN5O4
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1
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| 1 |
IC50 = 39.81 nM
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CP0962036
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2-Amino-N-((4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)-N-methylacetamide
Show/Hide
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C23H23ClN6O3
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1
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| 1 |
IC50 = 39.81 nM
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CP0436622
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(2R)-1-[5-[4-(phenylcarbamoylamino)phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C24H22N4O4
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1
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| 1 |
IC50 = 39.9 nM
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CP0530188
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2-[4-[4-[[5-(2-cyclohexylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C25H33N3O3S
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1
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| 1 |
IC50 = 40 nM
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CP0397580
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3,5-dimethyl-6-[4-[4-(2H-tetrazol-5-ylmethyl)-1-bicyclo[2.2.2]octanyl]phenyl]pyrazine-2-carboxamide
Show/Hide
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C23H27N7O
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1
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| 1 |
IC50 = 40 nM
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CP0544044
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4-[5-[[3-(difluoromethyl)-1-benzofuran-2-carbonyl]amino]pyridin-2-yl]-N-(2-fluorophenyl)piperazine-1-carboxamide
Show/Hide
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C26H22F3N5O3
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1
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| 1 |
IC50 = 40 nM
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CP0444007
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4-amino-6-[4-[4-(2-amino-2-methylpropyl)cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
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C23H31N5O2
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1
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| 1 |
IC50 = 40 nM
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CP0481065
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3-[[1-[5-[(3-butoxybenzoyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
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C29H33N3O5
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1
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| 1 |
IC50 = 41 nM
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CP0462265
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2-[4-[4-[5-[(5-cyclobutyl-1,3,4-oxadiazol-2-yl)amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C25H28N4O3
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1
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| 1 |
IC50 = 41 nM
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CP0433363
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4-[5-[(3,5-dimethyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]-N-(2-fluorophenyl)piperazine-1-carboxamide
Show/Hide
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C27H26FN5O3
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1
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| 1 |
IC50 = 42 nM
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CP0295271
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CHEMBL3287865
Show/Hide
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C30H32N2O4
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1
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| 1 |
IC50 = 43 nM
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CP0502365
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1-(3-Ethoxyphenyl)-N-(2-{[(4-ethoxyphenyl)carbonyl]amino}ethyl)-3-(trifluoromethyl)-1Hpyrazole-4-carboxamide
Show/Hide
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C24H25F3N4O4
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1
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| 1 |
IC50 = 44 nM
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CP0504338
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N-[2-[[2-phenyl-5-(trifluoromethyl)-1H-imidazole-4-carbonyl]amino]ethyl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
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C21H17F6N5O3
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1
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| 1 |
IC50 = 44 nM
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CP0430753
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2-[4-[4-[[5-[(4-fluorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C24H24FN3O4S
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1
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| 1 |
IC50 = 44 nM
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CP0525068
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2-[4-[4-[[5-[(2-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C24H24FN3O3S
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1
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| 1 |
IC50 = 45 nM
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CP0444006
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4-amino-6-[4-[4-(2-oxo-2-pyrrolidin-1-ylethyl)cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
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C25H31N5O3
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1
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| 1 |
IC50 = 45 nM
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CP0400125
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2-[4-[4-[[5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C24H25N3O4S
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1
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| 1 |
IC50 = 47 nM
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CP0513576
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2-(4-chlorophenyl)-5-[2-(2,6-dichlorophenyl)-3H-benzimidazol-5-yl]-1,3,4-oxadiazole
Show/Hide
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C21H11Cl3N4O
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1
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| 1 |
IC50 = 47 nM
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CP0401552
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6-Chloro-N-[2-({[1-phenyl-3-(trifluoromethyl)-1Hpyrazol-4-yl]carbonyl}amino)ethyl]pyridine-3-carboxamide
Show/Hide
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C19H15ClF3N5O2
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1
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| 1 |
IC50 = 49 nM
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CP0497337
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2,2-dimethyl-3-[5-[4-(naphthalene-2-carbonylamino)phenyl]pyridin-2-yl]oxypropanoic acid
Show/Hide
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C27H24N2O4
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1
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| 1 |
IC50 = 49 nM
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CP0430762
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2-[4-[4-[[5-[3-(4-fluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C26H28FN3O3S
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1
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| 1 |
IC50 = 50 nM
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CP0375926
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4-amino-6-[4-[4-[2-(4-methoxypiperidin-1-yl)-2-oxoethyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
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C27H35N5O4
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1
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| 1 |
IC50 = 50 nM
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CP0876335
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N-((4'-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)acetamide
Show/Hide
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C22H20ClN5O3
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1
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| 1 |
IC50 = 50.12 nM
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CP0883347
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4-Amino-6-(2'-chloro-4'-(2-oxo-2-(3-oxopiperazin-1-yl)ethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
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C25H23ClN6O4
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1
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| 1 |
IC50 = 50.12 nM
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CP0925467
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N-((4'-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)-N-methylacetamide
Show/Hide
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C23H22ClN5O3
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1
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| 1 |
IC50 = 50.12 nM
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CP0949741
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3-Amino-N-((4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)-N-methylpropanamide
Show/Hide
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C24H25ClN6O3
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1
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| 1 |
IC50 = 50.12 nM
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CP0949774
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4'-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-carbonitrile
Show/Hide
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C20H14ClN5O2
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1
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| 1 |
IC50 = 50.12 nM
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CP0962037
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4-Amino-N-((4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)-N-methylbutanamide
Show/Hide
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C25H27ClN6O3
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1
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| 1 |
IC50 = 50.12 nM
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CP0531606
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N-(2-fluorophenyl)-4-[5-[(5-methoxy-3-methyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carboxamide
Show/Hide
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C27H26FN5O4
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1
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| 1 |
IC50 = 51 nM
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CP0153605
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3-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
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C34H31N3O5
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1
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| 1 |
IC50 = 52 nM
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CP0453202
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2-[4-[4-[4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C29H30N2O4
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1
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| 1 |
IC50 = 52 nM
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CP0452107
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N-[4-[5-[3-[2-(dimethylamino)ethylamino]-2,2-dimethyl-3-oxopropoxy]-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
Show/Hide
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C29H34N6O3
|
1
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| 1 |
IC50 = 53 nM
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CP0522954
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3-[[1-[5-[(4-phenoxybenzoyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
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C31H29N3O5
|
1
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| 1 |
IC50 = 54 nM
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CP0488554
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N-(2-fluorophenyl)-4-[5-[(3-methyl-1-benzothiophene-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carboxamide
Show/Hide
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C26H24FN5O2S
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1
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| 1 |
IC50 = 55 nM
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CP0455442
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LCQ-908-NXA
Show/Hide
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C25H24F3N3O2
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1
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| 1 |
IC50 = 55 nM
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CP0461832
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2-[4-[6-[(3,4-dimethylphenyl)carbamoyl]-1H-benzimidazol-2-yl]-3,5-dimethylanilino]acetic acid
Show/Hide
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C26H26N4O3
|
1
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| 1 |
IC50 = 56 nM
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CP0466199
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2-[4-[4-(4-amino-2-methyl-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
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C22H26N4O4
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1
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| 1 |
IC50 = 59 nM
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CP0407792
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(2S)-1-[5-[4-[[2-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyridine-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C25H21F3N4O4
|
1
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| 1 |
IC50 = 59.2 nM
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CP0548678
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N-(6-butoxypyridin-3-yl)-5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
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C18H18FN5O3
|
1
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| 1 |
IC50 = 60 nM
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CP0548679
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N-(6-anilinopyridin-3-yl)-5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
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C20H15FN6O2
|
1
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| 1 |
IC50 = 60 nM
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CP0147210
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3,5-dimethyl-6-[4-[4-(2H-tetrazol-5-ylmethyl)cyclohexyl]phenyl]pyrazine-2-carboxamide
Show/Hide
|
C21H25N7O
|
1
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| 1 |
IC50 = 60 nM
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CP0522917
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2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-fluorophenyl]cyclohexyl]acetic acid
Show/Hide
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C21H24FN3O3
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1
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| 1 |
IC50 = 60 nM
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CP0458755
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4-[5-[[3-(fluoromethyl)-1-benzofuran-2-carbonyl]amino]pyridin-2-yl]-N-(2-fluorophenyl)piperazine-1-carboxamide
Show/Hide
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C26H23F2N5O3
|
1
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| 1 |
IC50 = 60 nM
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CP0075126
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4-amino-6-[4-[4-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
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C23H26N6O3
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1
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| 1 |
IC50 = 60 nM
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CP0443677
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US8637507, C-65
Show/Hide
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C27H27N3O5
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1
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| 1 |
IC50 = 60 nM
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CP0385342
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N-[1-[[1-(4-fluoro-2-methylphenyl)-5-(4-fluorophenyl)-1,2,4-triazol-3-yl]amino]-2-methyl-1-oxopropan-2-yl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
Show/Hide
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C24H22F5N5O2
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1
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| 1 |
IC50 = 62 nM
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CP0947164
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(S)-4-Amino-6-(2'-chloro-4'-((3-hydroxy-2-oxopyrrolidin-1-yl)methyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
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C24H22ClN5O4
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1
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| 1 |
IC50 = 63.1 nM
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CP0397266
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2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]-N-cyclopentylacetamide
Show/Hide
|
C26H33N5O3
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1
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| 1 |
IC50 = 64 nM
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CP0456207
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2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetonitrile
Show/Hide
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C21H23N5O2
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1
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| 1 |
IC50 = 64 nM
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CP0072887
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2-[4-[4-[(2R)-4-[(2-ethylphenyl)carbamoyl]-2-methyl-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C32H36N2O4
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1
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| 1 |
IC50 = 64 nM
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CP0430763
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2-[4-[4-[[5-(2-cyclobutylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C23H29N3O3S
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1
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| 1 |
IC50 = 65 nM
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CP0060386
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2-[4-[4-[4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C29H30N2O4
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1
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| 1 |
IC50 = 65 nM
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CP0400126
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2-[4-[4-[[5-[2-(4-fluorophenyl)ethyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C25H26FN3O3S
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1
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| 1 |
IC50 = 66 nM
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CP0503771
|
US8637507, C-87
Show/Hide
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C29H31N3O5
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1
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| 1 |
IC50 = 67 nM
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CP0756782
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{5-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]bicyclo[3.2.2]non-1-yl}acetic Acid
Show/Hide
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C24H28N4O3
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1
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| 1 |
IC50 = 69 nM
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CP0542199
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2-[4-[4-[4-[(4-ethoxyphenyl)carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C31H34N2O5
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1
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| 1 |
IC50 = 69 nM
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CP0400131
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2-[4-[4-[[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
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C25H27N3O3S
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1
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| 1 |
IC50 = 70 nM
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CP0441086
|
2-[3-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]phenyl]acetic acid
Show/Hide
|
C23H17FN4O4
|
1
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| 1 |
IC50 = 70 nM
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CP0436723
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-chlorophenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H24ClN3O3
|
1
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| 1 |
IC50 = 70 nM
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CP0538296
|
2-[[4-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carbonyl]amino]benzoic acid
Show/Hide
|
C33H29N5O5
|
1
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| 1 |
IC50 = 70 nM
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CP0528297
|
(1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid
Show/Hide
|
C27H20F4N2O4S
|
1
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| 1 |
IC50 = 73 nM
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CP0456204
|
4-amino-6-[4-[4-(2H-tetrazol-5-ylmethyl)cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C21H24N8O2
|
1
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| 1 |
IC50 = 76 nM
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CP0910947
|
1-Phenyl-N-[2-({[4-(1H-pyrazol-1-yl)phenyl]carbonyl}amino)ethyl]-3-(trifluoromethyl)-1Hpyrazole-4-carboxamide hydrochloride
Show/Hide
|
C23H20ClF3N6O2
|
1
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| 1 |
IC50 = 79 nM
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CP0481067
|
3-[[1-[5-[[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C29H32F3N5O5
|
1
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| 1 |
IC50 = 79 nM
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CP0390730
|
4-amino-6-[4-[1-(1,2-oxazole-5-carbonyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C22H22N6O4
|
1
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| 1 |
IC50 = 79 nM
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CP0866631
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4-amino-6-(2',3'-dichlorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H14Cl2N4O2
|
1
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| 1 |
IC50 = 79.43 nM
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CP0920914
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4-amino-6-(4-(3-chloropyridin-2-yl)phenyl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C18H14ClN5O2
|
1
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| 1 |
IC50 = 79.43 nM
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CP0948274
|
4-Amino-6-(2'-chloro-4'-((2-oxopyrimidin-1(2H)-yl)methyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C24H19ClN6O3
|
1
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| 1 |
IC50 = 79.43 nM
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CP0526486
|
2-[4-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]phenyl]acetic acid
Show/Hide
|
C23H17FN4O4
|
1
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| 1 |
IC50 = 80 nM
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CP0070847
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H25N3O3
|
1
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| 1 |
IC50 = 80 nM
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CP0368883
|
4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]bicyclo[2.2.2]octane-1-carboxylic acid
Show/Hide
|
C22H25N3O3
|
1
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| 1 |
IC50 = 80 nM
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CP0400137
|
2-[4-[4-[[5-[(2-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H24ClN3O3S
|
1
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| 1 |
IC50 = 82 nM
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CP0391157
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2-[4-[4-[4-[(5-cyclobutyl-1,3,4-oxadiazol-2-yl)amino]phenyl]phenyl]-2-oxabicyclo[2.2.2]octan-1-yl]acetic acid
Show/Hide
|
C27H29N3O4
|
1
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| 1 |
IC50 = 83 nM
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CP0430755
|
2-[4-[4-[(5-phenyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H23N3O3S
|
1
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| 1 |
IC50 = 85 nM
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CP0390732
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4-amino-6-[4-[1-(cyclohexanecarbonyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C25H31N5O3
|
1
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| 1 |
IC50 = 85 nM
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CP0456206
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2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]-N-[(2R)-1-hydroxy-3-methylbutan-2-yl]acetamide
Show/Hide
|
C26H35N5O4
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1
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| 1 |
IC50 = 85 nM
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CP0458503
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2-[4-[4-[(2S)-4-[(2-ethylphenyl)carbamoyl]-2-methyl-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C32H36N2O4
|
1
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| 1 |
IC50 = 85 nM
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CP0503772
|
US8637507, C-91
Show/Hide
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C28H25F4N3O5
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1
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| 1 |
IC50 = 85 nM
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CP0443679
|
US8637507, B-13
Show/Hide
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C26H35N3O5
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1
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| 1 |
IC50 = 87 nM
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CP0397265
|
4-amino-6-[4-(1-benzoylpiperidin-4-yl)phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C25H25N5O3
|
1
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| 1 |
IC50 = 88 nM
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CP0410019
|
CHEMBL3287864
Show/Hide
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C30H32N2O4
|
1
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| 1 |
IC50 = 91 nM
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CP0542198
|
2-[4-[4-[4-(4-phenylbutylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C33H38N2O4
|
1
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| 1 |
IC50 = 91 nM
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CP0525530
|
5-(3-chloroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17ClN6O3
|
1
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| 1 |
IC50 = 92 nM
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CP0374309
|
1-(4-Chlorophenyl)-N-(2-{[(4-ethoxyphenyl)carbonyl]amino}ethyl)-3-(trifluoromethyl)-1Hpyrazole-4-carboxamide
Show/Hide
|
C22H20ClF3N4O3
|
1
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| 1 |
IC50 = 94 nM
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CP0397264
|
2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]-N-ethylacetamide
Show/Hide
|
C23H29N5O3
|
1
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| 1 |
IC50 = 94 nM
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CP0487515
|
4-amino-6-[4-[4-(2-morpholin-4-yl-2-oxoethyl)cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C25H31N5O4
|
1
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| 1 |
IC50 = 94 nM
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CP0535409
|
(1S,2S)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}phenyl)carbonyl]cyclopentane-1-carboxylic acid
Show/Hide
|
C26H24N2O4
|
1
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| 1 |
IC50 = 96 nM
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CP0452165
|
2,2-dimethyl-3-[5-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyridin-2-yl]oxypropanoic acid
Show/Hide
|
C28H26N2O4
|
1
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| 1 |
IC50 = 97 nM
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CP0528799
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(1S,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}phenyl)carbonyl]cyclopentane-1-carboxylic acid
Show/Hide
|
C26H24N2O4
|
1
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| 1 |
IC50 = 98 nM
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CP0374310
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N-[2-[(4-ethoxybenzoyl)amino]ethyl]-1-(2-hydroxyphenyl)-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
|
C22H21F3N4O4
|
1
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| 1 |
IC50 = 98 nM
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CP0169787
|
6-[4-[4-[2-(methanesulfonamido)-2-oxoethyl]cyclohexyl]phenyl]-3,5-dimethylpyrazine-2-carboxamide
Show/Hide
|
C22H28N4O4S
|
1
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| 1 |
IC50 = 100 nM
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CP0115904
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2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-chlorophenyl]phenyl]acetic acid
Show/Hide
|
C21H18ClN3O3
|
1
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| 1 |
IC50 = 100 nM
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CP0192240
|
US8637507, C-3
Show/Hide
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C27H29N3O5
|
2
|
| 1 |
IC50 = 100 nM
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| 2 |
IC50 = 131 nM
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CP0441331
|
2,2-dimethyl-3-[4-[4-(naphthalene-2-carbonylamino)phenyl]phenoxy]propanoic acid
Show/Hide
|
C28H25NO4
|
1
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| 1 |
IC50 = 102 nM
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CP0458754
|
N-(2-fluorophenyl)-4-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carboxamide
Show/Hide
|
C32H28FN5O3
|
1
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| 1 |
IC50 = 103 nM
|
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CP0452113
|
N-[4-[5-(3-anilino-2,2-dimethyl-3-oxopropoxy)-4-methyl-1,2,4-triazol-3-yl]phenyl]naphthalene-2-carboxamide
Show/Hide
|
C31H29N5O3
|
1
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| 1 |
IC50 = 110 nM
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CP0239094
|
2-[4-[4-(6-carbamothioyl-3-methylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C20H23N3O2S
|
1
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| 1 |
IC50 = 110 nM
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CP0334134
|
2-[[2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetyl]amino]-2-methylpropanoic acid
Show/Hide
|
C25H32N4O4
|
1
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| 1 |
IC50 = 110 nM
|
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CP0458502
|
2-[4-[4-[2-ethyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C31H34N2O4
|
1
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| 1 |
IC50 = 110 nM
|
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CP0536762
|
2-[4-[4-[4-[(2-ethylphenyl)carbamoyl]-2-methyl-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C32H36N2O4
|
1
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| 1 |
IC50 = 110 nM
|
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CP0478903
|
4-amino-6-[4-[1-(4-hydroxycyclohexanecarbonyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C25H31N5O4
|
1
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| 1 |
IC50 = 113 nM
|
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CP0439980
|
2,2-dimethyl-3-[5-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyrimidin-2-yl]oxypropanoic acid
Show/Hide
|
C27H25N3O4
|
1
|
| 1 |
IC50 = 115 nM
|
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CP0544042
|
3-[[1-[5-(naphthalene-2-carbonylamino)pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C29H27N3O4
|
1
|
| 1 |
IC50 = 116 nM
|
|
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CP0495430
|
2,2-dimethyl-3-[5-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyrazin-2-yl]oxypropanoic acid
Show/Hide
|
C27H25N3O4
|
1
|
| 1 |
IC50 = 117 nM
|
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CP0520553
|
US8637507, C-5
Show/Hide
|
C27H27ClFN3O5
|
1
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| 1 |
IC50 = 118 nM
|
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CP0540770
|
3-[[(3S)-1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]pyrrolidin-3-yl]methoxy]benzoic acid
Show/Hide
|
C33H29N3O5
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
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CP0561072
|
US8637507, C-8
Show/Hide
|
C26H25ClFN3O5
|
1
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| 1 |
IC50 = 119 nM
|
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CP0037327
|
2-[3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)adamantan-1-yl]acetic acid
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
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CP0416908
|
5-(2-fluoroanilino)-N-(4-phenylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C21H15FN4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0441062
|
3-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]propanoic acid
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0447975
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2-fluorophenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H24FN3O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0488552
|
CHEMBL2178370
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0544043
|
2-[3-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]phenyl]acetic acid
Show/Hide
|
C35H33N3O5
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0459254
|
2-[4-[4-[5-[(5-cyclobutyl-1,3,4-oxadiazol-2-yl)amino]pyridin-2-yl]phenyl]-2-oxabicyclo[2.2.2]octan-1-yl]acetic acid
Show/Hide
|
C26H28N4O4
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0433362
|
3-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]oxymethyl]benzoic acid
Show/Hide
|
C34H31N3O5
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0718159
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2'-fluorobiphenyl-4-yl)acetic acid
Show/Hide
|
C21H18FN3O3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0856538
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2'-methylbiphenyl-4-yl)acetic acid
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0427507
|
2-[[4-methyl-5-[4-[(4-methylbenzoyl)amino]phenyl]-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
|
C20H20N4O3S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0480120
|
5-(2-fluoroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17FN6O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0500121
|
US8637507, C-56
Show/Hide
|
C26H25ClFN3O5
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0510321
|
5-(4-chlorophenyl)-2-[2-(2,6-dichlorophenyl)-3H-benzimidazol-5-yl]-1,3-oxazole
Show/Hide
|
C22H12Cl3N3O
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0390735
|
4-amino-6-(4-tert-butylphenyl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0520552
|
US8637507, B-4
Show/Hide
|
C25H25N3O5
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0485295
|
1-(4-Ethoxyphenyl)-N-(2-{[(4-ethoxyphenyl)carbonyl]amino}ethyl)-3-(trifluoromethyl)-1Hpyrazole-4-carboxamide
Show/Hide
|
C24H25F3N4O4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0389400
|
2-[4-[4-[4-[(2-propan-2-ylphenyl)carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C32H36N2O4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0496052
|
2-[[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]oxy]propanoic acid
Show/Hide
|
C23H20N4O4
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0433327
|
4-[5-(1-benzofuran-2-carbonylamino)pyridin-2-yl]-N-(2-fluorophenyl)piperazine-1-carboxamide
Show/Hide
|
C25H22FN5O3
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0444005
|
2-[4-[4-(4-amino-8,8-dimethyl-5-oxo-7H-pyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H28N4O4
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0466198
|
4-amino-6-[4-[4-[2-[(3R)-3-hydroxypyrrolidin-1-yl]-2-oxoethyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C25H31N5O4
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0507437
|
3-[[1-[5-[(4-phenylmethoxybenzoyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C32H31N3O5
|
1
|
| 1 |
IC50 = 149 nM
|
|
|
|
CP0524995
|
5-(3-fluoroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17FN6O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0391156
|
2-[4-[4-[5-[(5-ethyl-1,3,4-oxadiazol-2-yl)amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H26N4O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0488079
|
3-[[(3R)-1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]pyrrolidin-3-yl]methoxy]benzoic acid
Show/Hide
|
C33H29N3O5
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0551373
|
US8637507, C-68
Show/Hide
|
C28H29N3O5
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0400136
|
2-[4-[4-[[5-(1-phenylcyclopropyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C26H27N3O3S
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0388733
|
3-[4-methyl-5-[4-(naphthalene-2-carbonylamino)phenyl]-1,2,4-triazol-3-yl]propanoic acid
Show/Hide
|
C23H20N4O3
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0436399
|
5-(3-methylanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H20N6O3
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0436721
|
6-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)spiro[1,2-dihydroindene-3,4'-cyclohexane]-1'-carboxylic acid
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0487514
|
4-amino-6-[4-[4-[2-(4-methyl-3-oxopiperazin-1-yl)-2-oxoethyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C26H32N6O4
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0397262
|
4-amino-6-[4-[1-(1,2-oxazole-3-carbonyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C22H22N6O4
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
|
CP0397263
|
4-amino-6-[4-[1-(2-methylpropanoyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
|
CP0548684
|
5-[[1-(4-chlorophenyl)cyclopentanecarbonyl]amino]-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C25H26ClN5O4
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0444061
|
4-amino-6-[4-[4-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C23H26N6O2S
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0524151
|
5-(4-chloroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17ClN6O3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0548675
|
5-(2-fluoroanilino)-N-(4-piperidin-1-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C20H20FN5O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0488081
|
N-[6-[4-[(2-fluorophenyl)carbamoyl]piperazin-1-yl]pyridin-3-yl]-1-methylindole-2-carboxamide
Show/Hide
|
C26H25FN6O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0433347
|
3-[[1-[5-[[3-methyl-5-(1,3-thiazol-2-yl)-1-benzofuran-2-carbonyl]amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C31H28N4O5S
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0397261
|
6-[4-(1-acetylpiperidin-4-yl)phenyl]-4-amino-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C20H23N5O3
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0798362
|
(S)-2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)biphenyl-4-yl)propanoic acid
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0462145
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]-1-bicyclo[2.2.2]octanyl]acetic acid
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0525531
|
4-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]benzoic acid
Show/Hide
|
C22H15FN4O4
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0444060
|
4-amino-6-[4-[4-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0397259
|
4-amino-6-[4-[1-(oxane-4-carbonyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C24H29N5O4
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0482684
|
2-[4-[4-[(5-benzylsulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H25N3O3S2
|
1
|
| 1 |
IC50 = 218 nM
|
|
|
|
CP0510120
|
1-Cyclohexyl-N-(2-{[(4-ethoxyphenyl)carbonyl]amino}-ethyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C22H27F3N4O3
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0452164
|
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
|
C19H16Cl2N4O3S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0410021
|
2-[4-[4-[4-(cyclohexylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C29H36N2O4
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0447923
|
6-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)spiro[1,2-dihydroindene-3,4'-cyclohexane]-1'-carboxylic acid
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0510850
|
3-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyrimidin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C33H30N4O5
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0375925
|
4-amino-6-[4-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C24H29N5O4
|
1
|
| 1 |
IC50 = 249 nM
|
|
|
|
CP0037324
|
3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl}phenyl)adamantane-1-carboxylic acid
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0894341
|
4-amino-6-(biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0503674
|
US8637507, C-1
Show/Hide
|
C26H27N3O5
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
|
CP0390733
|
4-amino-6-[4-[1-(2-ethoxyacetyl)piperidin-4-yl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C22H27N5O4
|
1
|
| 1 |
IC50 = 274 nM
|
|
|
|
CP0246522
|
US8637507, B-17
Show/Hide
|
C27H25N3O4
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0522956
|
4-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C34H31N3O5
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0520554
|
US8637507, C-60
Show/Hide
|
C30H31N3O4
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0574307
|
N-(4-chlorophenyl)-2-(2,6-dichlorophenyl)-3H-benzimidazole-5-carboxamide
Show/Hide
|
C20H12Cl3N3O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0536763
|
1-[[5-[2-ethyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]pyridin-2-yl]oxymethyl]cyclobutane-1-carboxylic acid
Show/Hide
|
C28H29N3O5
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0542947
|
5-anilino-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H19N5O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0400714
|
7-[4-[4-[2-(hydroxyamino)-2-oxoethyl]cyclohexyl]phenyl]-N-phenyl-2,3-dihydro-1,4-benzoxazine-4-carboxamide
Show/Hide
|
C29H31N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0437775
|
N-(4-cyclohexylphenyl)-5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C21H21FN4O2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0210954
|
2-[4-[4-(6-carbamoyl-3-methylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C20H23N3O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0522958
|
2-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C34H31N3O5
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0540616
|
4-amino-6-[4-[4-[(4,5-dimethyl-1,2,4-triazol-3-yl)methyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C24H29N7O2
|
1
|
| 1 |
IC50 = 312 nM
|
|
|
|
CP0843877
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2'-cyanobiphenyl-4-yl)acetic acid
Show/Hide
|
C22H18N4O3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0947166
|
4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-3-carbonitrile
Show/Hide
|
C20H14ClN5O2
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0441085
|
5-[[1-(4-chlorophenyl)cyclobutanecarbonyl]amino]-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C24H24ClN5O4
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0548682
|
5-(3,4-difluoroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H16F2N6O3
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0522955
|
3-[[1-[5-[[3-methyl-5-(1,3-oxazol-2-yl)-1-benzofuran-2-carbonyl]amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C31H28N4O6
|
1
|
| 1 |
IC50 = 344 nM
|
|
|
|
CP0476412
|
2-[[5-(4-benzamidophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
|
C19H18N4O3S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0537157
|
CHEMBL2012624
Show/Hide
|
C25H27N3O3S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0542949
|
5-(2-fluoroanilino)-N-(3-methyl-4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C20H20FN5O3
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0400716
|
N-phenyl-7-[4-[4-(2H-tetrazol-5-ylmethyl)cyclohexyl]phenyl]-2,3-dihydro-1,4-benzoxazine-4-carboxamide
Show/Hide
|
C29H30N6O2
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0399817
|
5-[(4-chlorobenzoyl)amino]-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C20H18ClN5O4
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0431603
|
2,2-dimethyl-3-[6-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyridazin-3-yl]oxypropanoic acid
Show/Hide
|
C27H25N3O4
|
1
|
| 1 |
IC50 = 373 nM
|
|
|
|
CP0411042
|
2-[4-[4-[5-[(2-ethyl-4-methyl-1,3-oxazole-5-carbonyl)amino]pyridin-2-yl]phenyl]-2-oxabicyclo[2.2.2]octan-1-yl]acetic acid
Show/Hide
|
C27H29N3O5
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0456205
|
4-amino-6-[4-[4-[(5-methyl-1H-1,2,4-triazol-3-yl)methyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C23H27N7O2
|
1
|
| 1 |
IC50 = 391 nM
|
|
|
|
CP0481066
|
3-[[1-[5-[(4-benzoylbenzoyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C32H29N3O5
|
1
|
| 1 |
IC50 = 392 nM
|
|
|
|
CP0492116
|
2-[4-[4-[[5-[1-(4-fluorophenyl)cyclopropyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C26H26FN3O3S
|
1
|
| 1 |
IC50 = 408 nM
|
|
|
|
CP0424425
|
5-(2-fluoroanilino)-N-(6-pyridin-3-yloxypyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H13FN6O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0499583
|
2-[4-[4-[6-carbamoyl-5-(difluoromethyl)-3-methylpyrazin-2-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H23F2N3O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0453203
|
1-[[5-[2-ethyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]pyridin-2-yl]oxymethyl]cyclopropane-1-carboxylic acid
Show/Hide
|
C27H27N3O5
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0525069
|
CHEMBL2012615
Show/Hide
|
C22H27N3O3S
|
1
|
| 1 |
IC50 = 426 nM
|
|
|
|
CP0488521
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H25N3O3
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0452813
|
2-[4-[4-[4-(phenylcarbamoyl)-2-propyl-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C32H36N2O4
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0480124
|
5-(2-fluoroanilino)-N-(3-fluoro-4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H17F2N5O3
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0542950
|
5-(2-fluoroanilino)-N-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H20FN7O2
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0530075
|
3-[[1-[5-(quinoline-2-carbonylamino)pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C28H26N4O4
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0488077
|
3-[[1-[2-fluoro-4-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]phenyl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C35H31FN2O5
|
1
|
| 1 |
IC50 = 482 nM
|
|
|
|
CP0430754
|
2-[4-[4-[[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H27N3O3S
|
1
|
| 1 |
IC50 = 498 nM
|
|
|
|
CP0453586
|
N-(3,4-dimethylphenyl)-2-(4-methoxy-2,6-dimethylphenyl)-3H-benzimidazole-5-carboxamide
Show/Hide
|
C25H25N3O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0507621
|
N-[6-[4-[(2-fluorophenyl)carbamoyl]piperazin-1-yl]pyridin-3-yl]-2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
Show/Hide
|
C26H27F4N7O3
|
1
|
| 1 |
IC50 = 513 nM
|
|
|
|
CP0462094
|
2,2-dimethyl-3-[4-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]phenoxy]propanoic acid
Show/Hide
|
C29H27NO4
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0378153
|
5-(2-fluoroanilino)-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H18FN5O3
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0410190
|
5-[[2-(4-chlorophenyl)-2-methylpropanoyl]amino]-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C23H24ClN5O4
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0169788
|
6-[4-[4-(2-amino-2-oxoethyl)cyclohexyl]phenyl]-3,5-dimethylpyrazine-2-carboxamide
Show/Hide
|
C21H26N4O2
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0410022
|
2-[4-[4-[(2S)-2-methyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H32N2O4
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0524798
|
N-(6-morpholin-4-ylpyridin-3-yl)-5-[3-(pyridin-2-ylmethoxy)anilino]-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C24H23N7O4
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0548677
|
N-[4-(4-acetylpiperazin-1-yl)phenyl]-5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C21H21FN6O3
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0462264
|
2-[4-[4-[5-[(5-methyl-1,3,4-oxadiazol-2-yl)amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0479246
|
2-[4-[4-[4-[(2-ethyl-4-methyl-1,3-oxazole-5-carbonyl)amino]phenyl]phenyl]-2-oxabicyclo[2.2.2]octan-1-yl]acetic acid
Show/Hide
|
C28H30N2O5
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0452814
|
2-[4-[4-[4-(phenylcarbamoyl)-2-propan-2-yl-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C32H36N2O4
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0522515
|
2-[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H25N3O3S
|
1
|
| 1 |
IC50 = 578 nM
|
|
|
|
CP0389401
|
2-[4-[4-[4-(2-phenylacetyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H31NO4
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0415379
|
2-[4-[4-[4-(benzylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H32N2O4
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0381136
|
2-[4-[4-(6-carbamoyl-5-methylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C20H23N3O3
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0313002
|
2-[4-[4-[[5-[(4-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H24FN3O3S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0437776
|
5-anilino-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H18N6O3
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0524994
|
N-(4-butylphenyl)-5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0489399
|
2-[4-[4-[(8S)-4-amino-8-methyl-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
IC50 = 625 nM
|
|
|
|
CP0458504
|
(1R,2R)-2-[4-[4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]benzoyl]cyclopentane-1-carboxylic acid
Show/Hide
|
C28H26N2O5
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0240422
|
2-[4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]phenyl]acetic acid
Show/Hide
|
C21H19N3O3
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0400715
|
3-[5-[2-ethyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]pyrimidin-2-yl]oxy-2,2-dimethylpropanoic acid
Show/Hide
|
C26H28N4O5
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0485297
|
N-[2-[(4-ethoxybenzoyl)amino]ethyl]-3-methyl-1-phenylpyrazole-4-carboxamide
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0147213
|
6-[4-[4-(2-hydroxyethyl)cyclohexyl]phenyl]-3,5-dimethylpyrazine-2-carboxamide
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0373087
|
5-benzyl-N-(2-(4-ethoxybenzamido)ethyl)-4-phenylthiazole-2-carboxamide
Show/Hide
|
C28H27N3O3S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0522514
|
2-[4-[4-[[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
IC50 = 728 nM
|
|
|
|
CP0524992
|
5-(3-methoxyanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H20N6O4
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0536366
|
N-[1-[[1,5-bis(4-fluorophenyl)-1,2,4-triazol-3-yl]amino]-2-methyl-1-oxopropan-2-yl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H20F5N5O2
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0488078
|
3-[[1-[4-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]phenyl]piperidin-4-yl]methoxy]benzoic acid
Show/Hide
|
C35H32N2O5
|
1
|
| 1 |
IC50 = 774 nM
|
|
|
|
CP0497302
|
1-Benzyl-N-(2-{[(4-ethoxyphenyl)carbonyl]amino}-ethyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O3
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0721721
|
(R)-2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)biphenyl-4-yl)propanoic acid
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0522516
|
2-[4-[4-[[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H25N3O4S
|
1
|
| 1 |
IC50 = 838 nM
|
|
|
|
CP0525529
|
5-(4-fluoroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17FN6O3
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0458505
|
(1S,2S)-2-[[5-[2-ethyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]pyridin-2-yl]oxymethyl]cyclopropane-1-carboxylic acid
Show/Hide
|
C27H27N3O5
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0410020
|
2-[4-[4-[4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]propanoic acid
Show/Hide
|
C30H32N2O4
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0482683
|
2-[4-[4-[[5-(1-adamantyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C27H33N3O3S
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0486730
|
(1R,2R)-2-({4-[4-({[3-(methylcarbamoyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid
Show/Hide
|
C28H27N3O5
|
1
|
| 1 |
IC50 = 994 nM
|
|
|
|
CP0057033
|
4-[4-(6-carbamoyl-3-methylpyrazin-2-yl)phenyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C19H21N3O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0260464
|
2-[[2-[4-[4-(6-carbamoylpyrazin-2-yl)phenyl]cyclohexyl]acetyl]amino]-2-methylpropanoic acid
Show/Hide
|
C23H28N4O4
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0416981
|
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-2-phenylacetic acid
Show/Hide
|
C24H18Cl2N4O3S
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0430765
|
CHEMBL2012604
Show/Hide
|
C21H26N4O4S
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0522518
|
2-[4-[4-[(5-tert-butyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H27N3O3S
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0522918
|
6-[4-[4-(2-hydroxyethyl)cyclohexyl]phenyl]pyrazine-2-carboxamide
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0444059
|
2-[4-[4-(6-amino-5-oxo-2,3-dihydropyrido[3,4-f][1,4]oxazepin-4-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H25N3O4
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0672815
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-3-chlorobiphenyl-4-yl)acetic acid
Show/Hide
|
C21H18ClN3O3
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0383469
|
5-Chloro-N-[2-({[1-phenyl-3-(trifluoromethyl)-1Hpyrazol-4-yl]carbonyl}amino)ethyl]pyridine-2-carboxamide
Show/Hide
|
C19H15ClF3N5O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0437777
|
2-[4-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]cyclohexyl]phenyl]acetic acid
Show/Hide
|
C23H23FN4O4
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0524996
|
5-(2-chloroanilino)-N-(6-morpholin-4-ylpyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17ClN6O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0262750
|
ethyl N-[2-(2,6-dichlorophenyl)-3H-benzimidazol-5-yl]carbamate
Show/Hide
|
C16H13Cl2N3O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0526257
|
2-(2,6-dimethylphenyl)-N-(3,4-dimethylphenyl)-3H-benzimidazole-5-carboxamide
Show/Hide
|
C24H23N3O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0420106
|
N-[1-[[1-(4-fluorophenyl)-5-[2-(4-fluorophenyl)propan-2-yl]-1,2,4-triazol-3-yl]amino]-2-methyl-1-oxopropan-2-yl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
Show/Hide
|
C26H26F5N5O2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0410023
|
2-[4-[4-[4-[[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H28F4N2O4
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0476887
|
2-[4-[4-(6-carbamoyl-5-ethyl-3-methylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0473494
|
N-[2-[(4-ethoxybenzoyl)amino]ethyl]-1-pyridin-3-yl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
|
C21H20F3N5O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0147216
|
2-[4-[4-(6-carbamoylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C19H21N3O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0270869
|
6-[4-[4-(2-amino-2-oxoethyl)cyclohexyl]phenyl]pyrazine-2-carboxamide
Show/Hide
|
C19H22N4O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0389402
|
2-[4-[4-[1-(phenylcarbamoyl)-2,3-dihydropyrido[2,3-b][1,4]oxazin-6-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C28H29N3O4
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0260349
|
2-[[4-methyl-5-[4-[(2-methylbenzoyl)amino]phenyl]-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
Show/Hide
|
C20H20N4O3S
|
1
|
| 1 |
IC50 = 1980 nM
|
|
|
|
CP0383424
|
N-[2-[(4-ethoxybenzoyl)amino]ethyl]-4-methyl-1-phenylpyrazole-3-carboxamide
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0399829
|
N-(6-morpholin-4-ylpyridin-3-yl)-5-[3-(pyridin-3-ylmethoxy)anilino]-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C24H23N7O4
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0375921
|
4-amino-6-(4-methylphenyl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C14H14N4O2
|
1
|
| 1 |
IC50 = 2210 nM
|
|
|
|
CP0522517
|
CHEMBL2012618
Show/Hide
|
C26H26FN3O3S
|
1
|
| 1 |
IC50 = 2360 nM
|
|
|
|
CP0467487
|
2,2-dimethyl-3-[6-[2-methyl-4-(naphthalene-2-carbonylamino)phenyl]pyridin-3-yl]oxypropanoic acid
Show/Hide
|
C28H26N2O4
|
1
|
| 1 |
IC50 = 2420 nM
|
|
|
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CP0536474
|
N-[1-[(4-ethoxybenzoyl)amino]propan-2-yl]-1-phenyl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O3
|
1
|
| 1 |
IC50 = 2800 nM
|
|
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CP0400132
|
2-[4-[4-[(5-bromo-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C17H18BrN3O3S
|
1
|
| 1 |
IC50 = 2840 nM
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|
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CP0448857
|
(1R,2R)-2-[4-[1-(phenylcarbamoyl)indol-5-yl]benzoyl]cyclopentane-1-carboxylic acid
Show/Hide
|
C28H24N2O4
|
1
|
| 1 |
IC50 = 2900 nM
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|
|
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CP0390729
|
4-amino-6-(4-tert-butylcyclohexyl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C17H26N4O2
|
1
|
| 1 |
IC50 = 2950 nM
|
|
|
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CP0375920
|
2-[4-[4-(4-amino-7,8-dihydro-5H-pyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]ethanol
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
IC50 = 2960 nM
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|
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CP0400717
|
2-[4-[4-[3-methyl-4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H32N2O4
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0542200
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7-[4-[4-[2-(methanesulfonamido)-2-oxoethyl]cyclohexyl]phenyl]-N-phenyl-2,3-dihydro-1,4-benzoxazine-4-carboxamide
Show/Hide
|
C30H33N3O5S
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
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CP0432910
|
4-[4-[[5-(2-fluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]butanoic acid
Show/Hide
|
C19H17FN4O4
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
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CP0555746
|
N-[1-[[5-tert-butyl-1-(4-fluorophenyl)-1,2,4-triazol-3-yl]amino]-2-methyl-1-oxopropan-2-yl]-4-fluorobenzamide
Show/Hide
|
C23H25F2N5O2
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0374311
|
N-[2-[(3-ethoxybenzoyl)amino]ethyl]-1-phenyl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 3600 nM
|
|
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CP0480125
|
5-(2-fluoroanilino)-N-[6-(1-oxo-1,4-thiazinan-4-yl)pyridin-3-yl]-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17FN6O3S
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
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CP0558500
|
2-[4-[4-[4-[(2S)-2-amino-2-phenylacetyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H32N2O4
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
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CP0525070
|
2-[4-[4-[(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
IC50 = 4770 nM
|
|
|
|
CP0566700
|
N-[1-[[5-tert-butyl-1-(4-fluorophenyl)-1,2,4-triazol-3-yl]amino]-2-methyl-1-oxopropan-2-yl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
Show/Hide
|
C21H25F4N5O2
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0525262
|
5-benzamido-N-(4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C20H19N5O4
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0397906
|
2-[4-[4-[[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C24H24ClN3O3S
|
1
|
| 1 |
IC50 = 5280 nM
|
|
|
|
CP0470260
|
N-[2-[(4-ethoxybenzoyl)amino]propyl]-1-phenyl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O3
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0401551
|
N-[2-[(4-ethoxybenzoyl)amino]ethyl]-1-pyridin-4-yl-3-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
|
C21H20F3N5O3
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0400718
|
2-[4-[4-[4-[(2-aminophenyl)carbamoyl]-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C29H31N3O4
|
1
|
| 1 |
IC50 = 6100 nM
|
|
|
|
CP0664170
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-3'-chlorobiphenyl-4-yl)acetic acid
Show/Hide
|
C21H18ClN3O3
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0843878
|
2-(4'-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)-2'-methoxybiphenyl-4-yl)acetic acid
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0542951
|
5-(2-fluoroanilino)-N-(6-methoxypyridin-3-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C15H12FN5O3
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0497303
|
(R)-N-(2-{[(4-Ethoxyphenyl)carbonyl]amino}-3-hydroxypropyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0508033
|
(S)-N-(2-{[(4-Ethoxyphenyl)carbonyl]amino}-3-hydroxypropyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0508034
|
(S)-N-[2-{[(4-Ethoxyphenyl)carbonyl]amino}-1-(hydroxymethyl)ethyl]-1-phenyl-3-(trifluoromethyl)-1Hpyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0536472
|
(R)-N-[2-{[(4-Ethoxyphenyl)carbonyl]amino}-1-(hydroxymethyl)ethyl]-1-phenyl-3-(trifluoromethyl)-1Hpyrazole-4-carboxamide
Show/Hide
|
C23H23F3N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400134
|
2-[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)amino]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H25N3O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0430756
|
2-[4-[4-[(5-methylsulfonyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C18H21N3O5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0430760
|
CHEMBL2012635
Show/Hide
|
C25H27N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0397581
|
2-[4-[4-(6-carbamoyl-5-methyl-3-phenylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0428752
|
2-[4-[4-(6-carbamoyl-3-methyl-5-phenylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0428753
|
2-[4-[4-(6-carbamoyl-3-methyl-5-propan-2-ylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0436724
|
2-[4-[4-(6-carbamoyl-5-methyl-3-propan-2-ylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0553442
|
2-[4-[4-(5-amino-6-carbamoylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C19H22N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0054525
|
(3S)-N-[4-(difluoromethoxy)phenyl]-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H19F2N3O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0067043
|
(3S)-3-ethyl-3-methyl-2,5-dioxo-N-[4-(trifluoromethyl)phenyl]-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H18F3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0067044
|
3-ethyl-3-methyl-2,5-dioxo-N-phenyl-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C18H19N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0145140
|
(3S)-N-(2,4-difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C18H17F2N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0283294
|
N-(2,4-difluorophenyl)-3,3-diethyl-5-oxo-2,4-dihydro-1H-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H21F2N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0283295
|
3-ethyl-N,3-dimethyl-2,5-dioxo-N-phenyl-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H21N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0318556
|
N-(2-chlorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C18H18ClN3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0338873
|
3-ethyl-N-(4-methoxyphenyl)-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H21N3O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0347555
|
N-(2,4-difluorophenyl)-3-ethyl-3,4-dimethyl-2,5-dioxo-1H-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H19F2N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0359268
|
N-(4-chlorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C18H18ClN3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0363065
|
N-(4-chlorophenyl)-3-ethyl-1,3-dimethyl-2,5-dioxo-4H-1,4-benzodiazepine-7-sulfonamide
Show/Hide
|
C19H20ClN3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389394
|
2-[4-[4-[2-methyl-3-oxo-4-(phenylcarbamoyl)-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C30H30N2O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389395
|
2-[[7-[4-[4-(carboxymethyl)cyclohexyl]phenyl]-2,3-dihydro-1,4-benzoxazine-4-carbonyl]amino]benzoic acid
Show/Hide
|
C30H30N2O6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400746
|
2-[4-[4-[4-(phenylcarbamoyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C28H29N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400747
|
2-[4-[4-(4-benzylsulfonyl-2,3-dihydro-1,4-benzoxazin-7-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C29H31NO5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0410015
|
2-[4-[4-[4-(1,3-benzoxazol-2-yl)-2,3-dihydro-1,4-benzoxazin-7-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C29H28N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0473175
|
2-[4-[4-[4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-6-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C29H30N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0504879
|
2-[4-[4-[4-(phenylcarbamoyl)-2,3-dihydro-1,4-benzoxazin-8-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C29H30N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0474410
|
[(2S)-1-[3-[[(2S)-1-ethoxy-4-phenylbutan-2-yl]sulfamoyl]anilino]-4-methyl-1-oxopentan-2-yl] 2,2-dimethylpropanoate
Show/Hide
|
C29H42N2O6S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0487836
|
N-[1-[[5-tert-butyl-1-(4-fluorophenyl)-1,2,4-triazol-3-yl]amino]-2-methyl-1-oxopropan-2-yl]-1-methylcyclopropane-1-carboxamide
Show/Hide
|
C21H28FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0525527
|
5-(2-fluoroanilino)-N-(5-morpholin-4-ylpyridin-2-yl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C18H17FN6O3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0533414
|
2-[1-[4-[5-[(5-propan-2-yl-1,3,4-oxadiazol-2-yl)amino]pyridin-2-yl]phenyl]piperidin-4-yl]acetic acid
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 12600 nM
|
|
|
|
CP0521338
|
2-[4-[4-(6-carbamoylpyridin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
IC50 = 28000 nM
|
|
|
|
CP0399805
|
5-(2-fluoroanilino)-N-(2-fluoro-4-morpholin-4-ylphenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C19H17F2N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0548683
|
3-[[5-[(6-morpholin-4-ylpyridin-3-yl)carbamoyl]-1,3,4-oxadiazol-2-yl]amino]benzoic acid
Show/Hide
|
C19H18N6O5
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0493887
|
2-[4-[4-(6-carbamimidoylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C19H22N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0441064
|
2-[4-[4-(6-carbamoyl-3-methylpyridin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
|
CP0428754
|
2-[4-[4-(5-carbamoylpyridin-3-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
IC50 = 60000 nM
|
|
|
|
CP0375928
|
4-amino-6-cyclopentyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
Show/Hide
|
C12H16N4O2
|
1
|
| 1 |
IC50 = 92100 nM
|
|
|
|
CP0395758
|
2-[4-[4-(4-amino-7-oxo-5H-pyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H24N4O4
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0404024
|
2-[4-[4-(4,5-dioxo-7,8-dihydro-3H-pyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C21H23N3O5
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0444032
|
2-[4-[4-[4-(methylamino)-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0444033
|
2-[4-[4-(4-methoxy-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H25N3O5
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0493039
|
2-[4-[4-[4-(dimethylamino)-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C23H28N4O4
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0540911
|
2-[4-[4-(6-carbamoyl-3-ethyl-5-methylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
IC50 > 9100 nM
|
|
|
