Brief Information of the Compound and Protein
Compound Name
4-amino-6-[4-[4-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]cyclohexyl]phenyl]-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5-one
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Canonical SMILES
Cc1noc(C[C@H]2CC[C@@H](CC2)c2ccc(cc2)N2CCOc3ncnc(N)c3C2=O)n1
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Compound Formula C23H26N6O3
Compound Structure
Protein Name
Diacylglycerol O-acyltransferase 1
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O75907
Gene Name
DGAT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS