General Information of the Compound
Compound ID
CP0416981
Compound Name
2-[[5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-2-phenylacetic acid
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Structure
Formula
C24H18Cl2N4O3S
Molecular Weight
513.406
Canonical SMILES
Cn1c(SC(C(O)=O)c2ccccc2)nnc1-c1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1
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InChI
InChI=1S/C24H18Cl2N4O3S/c1-30-21(28-29-24(30)34-20(23(32)33)14-5-3-2-4-6-14)15-7-10-17(11-8-15)27-22(31)16-9-12-18(25)19(26)13-16/h2-13,20H,1H3,(H,27,31)(H,32,33)
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InChIKey
HCVRAOLSBVFSFU-UHFFFAOYSA-N
Physicochemical Property
logP
5.9592
Rotatable Bonds
7
Heavy Atom Count
34
Polar Areas
97.11
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57398967
ChEMBL ID
CHEMBL1939479
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02536, Diacylglycerol O-acyltransferase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1120 nM
   TI
   LI
   LO
   TS
Protein ID: PT02560, Diacylglycerol O-acyltransferase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000384 3T3-L1 Mus musculus (Mouse)  1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS