Brief Information of the Compound and Protein
Compound Name
2-[4-[4-[[5-(3,4-difluoroanilino)-1,3,4-oxadiazole-2-carbonyl]amino]phenyl]cyclohexyl]acetic acid
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PubChem ID
SID: 46520452
Canonical SMILES
OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(NC(=O)c2nnc(Nc3ccc(F)c(F)c3)o2)cc1
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Compound Formula C23H22F2N4O4
Compound Structure
Protein Name
Diacylglycerol O-acyltransferase 1
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O75907
Gene Name
DGAT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000492 HuTu 80 Homo sapiens (Human)  1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 IC50 = 36 nM