All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000012 , Sf21

Cell Line Info

Synonyms	SF21 Sf-21 SF-21 IPLB-SF-21-AE IPLB-Sf21-AE IPLB-SF21-AE IPLB-SF 21AE IPLB-Sf21AE IPLB-SF21AE IPLB-SF-21 IPLB-Sf-21 IPLB-SF 21 IPLB-Sf21 IPLB-SF21
Category	Spontaneously immortalized cell line
Organism	Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID	CVCL_0518

Protein ID: PT02490 , Cathepsin K

Protein Info

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000012

Cell Line Info

Protein ID: PT02490

Protein Info

Compound ID	Compound Name	Compound Formula
CP0064146 Compound Info	7-(2,2-Dimethyl-propyl)-6-(3-methyl-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile Show/Hide	C21H27N7O2	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0336743 Compound Info	7-(2,2-Dimethyl-propyl)-6-(2,4-dioxo-8-propyl-1,3,8-triaza-spiro[4.5]dec-3-ylmethyl)-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile Show/Hide	C23H31N7O2	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0064145 Compound Info	6-((1,3-dioxo-2,8-diazaspiro[4.5]decan-2-yl)methyl)-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile Show/Hide	C21H26N6O2	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0206244 Compound Info	7-(2,2-dimethylpropyl)-6-[(5-methoxy-2-oxospiro[indole-3,4'-piperidin]-1(2H)-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile Show/Hide	C26H30N6O2	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0151193 Compound Info	7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile Show/Hide	C20H25N7O2	1
1	IC50 = 76 nM Bioactivity Info	TI LI LO TS
CP0109230 Compound Info	7-(2,2-dimethylpropyl)-6-[(5-fluoro-2-oxospiro[indole-3,4'-piperidin]-1(2H)-yl)methyl]-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile Show/Hide	C25H27FN6O	1
1	IC50 = 78 nM Bioactivity Info	TI LI LO TS