Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(2,2-Dimethyl-propyl)-6-(3-methyl-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile
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 PubChem ID
CID: 10272927
SID: 15277895
Canonical SMILES
CN1C(=O)NC2(CCN(Cc3cc4cnc(nc4n3CC(C)(C)C)C#N)CC2)C1=O
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Compound Formula C21H27N7O2
Compound Structure
Protein Name
 Protein Info 
Cathepsin K
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
O35186
Gene Name
CTSK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 12 nM
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