Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(2,2-Dimethyl-propyl)-6-(2,4-dioxo-8-propyl-1,3,8-triaza-spiro[4.5]dec-3-ylmethyl)-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile
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 PubChem ID
CID: 25053852
SID: 56390123
Canonical SMILES
CCCN1CCC2(CC1)NC(=O)N(Cc1cc3cnc(nc3n1CC(C)(C)C)C#N)C2=O
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Compound Formula C23H31N7O2
Compound Structure
Protein Name
 Protein Info 
Cathepsin K
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
O35186
Gene Name
CTSK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 27 nM
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