Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(2,2-dimethylpropyl)-6-[(5-fluoro-2-oxospiro[indole-3,4'-piperidin]-1(2H)-yl)methyl]-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile
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 PubChem ID
CID: 10478741
SID: 15502609
Canonical SMILES
CC(C)(C)Cn1c(CN2C(=O)C3(CCNCC3)c3cc(F)ccc23)cc2cnc(nc12)C#N
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Compound Formula C25H27FN6O
Compound Structure
Protein Name
 Protein Info 
Cathepsin K
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
O35186
Gene Name
CTSK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 78 nM
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