US8598155, 13

2-(3,4-Dimethoxy-benzyl)-7-[(R)-1-((R)-1-hydroxy-ethyl)-4-phenyl-butyl]-5-methyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one

4-(3-fluoroazetidin-1-yl)-7-methyl-5-[1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazine

US8598155, 8

US8598155, 36

US11419874, PF-05180999

US8598155, 55

7-methyl-5-[1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazin-4-amine

US11419874, Example 15

5-[5-(4-Chloro-2-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-4-(3-fluoroazetidin-1-yl)-7-methylimidazo[5,1-f][1,2,4]triazine

US8829010, 9

US8598155, 53

1-(2,5-dichlorophenyl)-8-methoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine

US8829010, 33

US8829010, 17

US8829010, 7

8-chloro-1-(2,5-dichlorophenyl)-3-methylimidazo[5,1-c][1,2,4]benzotriazine

US8829010, 40

3-[5-(4-ethylphenyl)-1-methylpyrazol-4-yl]-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

3-[5-(4-ethylphenyl)-1-methylpyrazol-4-yl]-1-methyl-4-pyrrolidin-1-ylpyrazolo[3,4-d]pyrimidine

US8598155, 5

US8829010, 4

US8829010, 37

6-fluoro-1-(2-fluoro-5-methoxyphenyl)-8-methoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine

3-[1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

7-methyl-5-[1-methyl-5-[5-(trifluoromethyl)pyridin-2-yl]pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazin-4-amine

1-[1-methyl-3-[1-methyl-5-[5-(trifluoromethyl)pyridin-2-yl]pyrazol-4-yl]pyrazolo[3,4-d]pyrimidin-4-yl]azetidin-3-ol

US8829010, 1

5-[2-(2-methoxyphenyl)ethoxy]-3-[5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-[1,2,4]triazolo[4,3-a]pyrazine

3-[1-methyl-5-(4-methylphenyl)pyrazol-4-yl]-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

1-(2-chlorophenyl)-6,8-dimethoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine

6-fluoro-8-methoxy-1-(5-methoxypyridin-3-yl)-3-methylimidazo[5,1-c][1,2,4]benzotriazine

4-[3-(4-methoxyphenoxy)azetidin-1-yl]-1-methyl-3-(2-methylpropyl)pyrazolo[3,4-d]pyrimidine

3-[[1-methyl-3-[1-methyl-5-[5-(trifluoromethyl)pyridin-2-yl]pyrazol-4-yl]pyrazolo[3,4-d]pyrimidin-4-yl]amino]propanoic acid

6-methoxy-3-methyl-1-(3-methylpyridin-4-yl)-8-phenylmethoxyimidazo[5,1-c][1,2,4]benzotriazine

3-[5-(4-methoxyphenyl)-1-methylpyrazol-4-yl]-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

5-propoxy-3-[5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-[1,2,4]triazolo[4,3-a]pyrazine

4-(1,3-dihydroisoindol-2-yl)-1-methyl-3-(2-methylpropyl)pyrazolo[3,4-d]pyrimidine

4-(azetidin-1-yl)-1-methyl-3-(1-methyl-5-phenylpyrazol-4-yl)pyrazolo[3,4-d]pyrimidine

2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazine

3-[5-(4-fluorophenyl)-1-methylpyrazol-4-yl]-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

3-[5-(4-methylphenyl)-1H-pyrazol-4-yl]-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

6-methoxy-3-methyl-1-(3-methylpyridin-4-yl)-8-(trifluoromethyl)imidazo[5,1-c][1,2,4]benzotriazine

5-[2-(2-methoxyphenyl)ethoxy]-3-(2-methylpropyl)-[1,2,4]triazolo[4,3-a]pyrazine

4-[3-[5-(4-ethylphenyl)-1-methylpyrazol-4-yl]-1-methylpyrazolo[3,4-d]pyrimidin-4-yl]morpholine

3-(1-methyl-5-phenylpyrazol-4-yl)-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine

4-(azetidin-1-yl)-3-[5-(5-cyclopropylpyrimidin-2-yl)-1-methylpyrazol-4-yl]-1-methylpyrazolo[3,4-d]pyrimidine

8-fluoro-1-(3-fluoro-2-methylphenyl)-6-methoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine

3-[5-(4-ethylphenyl)-1-methylpyrazol-4-yl]-1-methyl-4-(4-methylpiperazin-1-yl)pyrazolo[3,4-d]pyrimidine

3-[5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-[1,2,4]triazolo[4,3-a]pyrazine

3-(2-methylpropyl)-5-propoxy-[1,2,4]triazolo[4,3-a]pyrazine