General Information of the Compound
| Compound ID |
CP0465365
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| Compound Name |
6-fluoro-1-(2-fluoro-5-methoxyphenyl)-8-methoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine
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| Structure |
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| Formula |
C18H14F2N4O2
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| Molecular Weight |
356.332
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| Canonical SMILES |
COc1ccc(F)c(c1)-c1nc(C)c2nnc3c(F)cc(OC)cc3n12
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| InChI |
InChI=1S/C18H14F2N4O2/c1-9-17-23-22-16-14(20)7-11(26-3)8-15(16)24(17)18(21-9)12-6-10(25-2)4-5-13(12)19/h4-8H,1-3H3
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| InChIKey |
OVFNIEPLLFYLGK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01875, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein ID: PT02047, cGMP-dependent 3',5'-cyclic phosphodiesterase