Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US11419874, PF-05180999
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 PubChem ID
CID: 60143346
SID: 143486328
Canonical SMILES
Cc1nc(-c2cnn(C)c2-c2ccc(cn2)C(F)(F)F)c2c(ncnn12)N1CCC1
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Compound Formula C19H17F3N8
Compound Structure
Protein Name
 Protein Info 
cGMP-dependent 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 2
>
Phosphodiesterase 2A
Uniprot ID
O00408
Gene Name
PDE2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM
2 IC50 = 1.61 nM