Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3,4-Dimethoxy-benzyl)-7-[(R)-1-((R)-1-hydroxy-ethyl)-4-phenyl-butyl]-5-methyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one
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 PubChem ID
CID: 135564787
Canonical SMILES
COc1ccc(Cc2nn3c(nc(C)c3c(=O)[nH]2)[C@@H](CCCc2ccccc2)[C@@H](C)O)cc1OC
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Compound Formula C27H32N4O4
Compound Structure
Protein Name
 Protein Info 
cGMP-dependent 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 2
>
Phosphodiesterase 2A
Uniprot ID
O00408
Gene Name
PDE2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.03 nM
2 IC50 = 0.86 nM
3 IC50 = 2 nM
4 IC50 = 4.7 nM
5 IC50 = 4.8 nM