Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
 Cell Line Info 
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT01201 , Hepatocyte growth factor receptor
 Protein Info 
Gene Name MET
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P08581
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012
 Cell Line Info 
 Protein ID: PT01201
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0552103
 Compound Info 
3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
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C22H22FN5
  1
1
IC50 = 44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558774
 Compound Info 
3-benzyl-5-(1-piperidin-4-ylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
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C22H23N5
  1
1
IC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557050
 Compound Info 
3-[(3-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
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C22H22FN5
  1
1
IC50 = 65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552062
 Compound Info 
3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
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C22H22FN5
  1
1
IC50 = 137 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557045
 Compound Info 
3-(3-benzyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-4,5-dihydro-1H-pyrrolo[3,4-b]pyrrol-6-one
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C20H16N4O
  2
1
IC50 = 660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Kd = 5300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570238
 Compound Info 
3-(3-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-4,5-dihydro-1H-pyrrolo[3,4-b]pyrrol-6-one
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C14H12N4O
  2
1
IC50 = 2900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Kd = 5100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557044
 Compound Info 
3-(6-fluoro-1H-indazol-4-yl)-4,5-dihydro-1H-pyrrolo[3,4-b]pyrrol-6-one
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C13H9FN4O
  2
1
IC50 = 9600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Kd = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0566240
 Compound Info 
3-benzyl-1H-pyrrolo[2,3-b]pyridine
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C14H12N2
  2
1
IC50 = 24200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Kd = 97000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0054448
 Compound Info 
6,6-dimethyl-8-[1-(oxan-4-ylmethyl)piperidin-4-yl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
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C30H33N3O2
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012721
 Compound Info 
[3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]pyridin-2-yl]methanone
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C30H34N2O6
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0469098
 Compound Info 
1-benzyl-5H-pyrrolo[3,2-c]pyridin-4-one
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C14H12N2O
  1
1
Kd > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS