Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(6-fluoro-1H-indazol-4-yl)-4,5-dihydro-1H-pyrrolo[3,4-b]pyrrol-6-one
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 PubChem ID
CID: 155804538
Canonical SMILES
Fc1cc(-c2c[nH]c3C(=O)NCc23)c2cn[nH]c2c1
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Compound Formula C13H9FN4O
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 9600 nM
   TI
   LI
   LO
   TS
2
Kd = 8000 nM
   TI
   LI
   LO
   TS