Brief Information of the Compound and Protein
Compound Name
3-[(3-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
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PubChem ID
CID: 155289350
Canonical SMILES
Fc1cccc(Cc2c[nH]c3ncc(cc23)-c2cnn(c2)C2CCNCC2)c1
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Compound Formula C22H22FN5
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000281 NCI-H1993 Homo sapiens (Human)  1
1
IC50 = 3120 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS