| Compound ID |
Compound Name |
Compound Formula |
|
CP0902360
|
Trans-5-Chloro-N-[4-(3-ethyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C23H27ClN4O2
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
|
CP0850734
|
Trans-5-Chloro-N-[4-(3-isobutyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C25H31ClN4O2
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0904714
|
US8835444, 1.8
Show/Hide
|
C26H27Cl2F3N4O2
|
1
|
| 1 |
IC50 = 727 nM
|
|
|
|
CP0871523
|
Trans-5-chloro-N-[-4-((5'-fluoro-2'-oxospiro[cyclopropane-1,3'-indoline]-1'-yl)methyl)cyclohexyl]-2-methylnicotinamide
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|
C24H25ClFN3O2
|
1
|
| 1 |
IC50 = 811 nM
|
|
|
|
CP0862006
|
Trans-5-Chloro-N-[4-(-6-chloro-3-fluoro-3-methyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C23H24Cl2FN3O2
|
1
|
| 1 |
IC50 = 876 nM
|
|
|
|
CP0860100
|
Trans-5-Chloro-N-[4-(7-chloro-3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C24H27Cl2N3O2
|
1
|
| 1 |
IC50 = 936 nM
|
|
|
|
CP0849230
|
Trans-2-Chloro-N-[4-(7-methoxy-3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide
Show/Hide
|
C26H28ClF3N2O3
|
1
|
| 1 |
IC50 = 1685 nM
|
|
|
|
CP0902358
|
Trans-2-Chloro-N-[4-(3-ethyl-2-oxo-2,3-dihydro-bcnzoimidazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide
Show/Hide
|
C24H25ClF3N3O2
|
1
|
| 1 |
IC50 = 1948 nM
|
|
|
|
CP0431983
|
US8835444, 5.27
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|
C21H25ClF3N3O
|
1
|
| 1 |
IC50 = 2026 nM
|
|
|
|
CP0849229
|
Trans-2-Chloro-5-trifluoromethyl-N-[4-(3,3,7-trimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-benzamide
Show/Hide
|
C26H28ClF3N2O2
|
1
|
| 1 |
IC50 = 2137 nM
|
|
|
|
CP0904389
|
Trans-5-Chloro-N-[4-(6-methoxy-3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C25H30ClN3O3
|
1
|
| 1 |
IC50 = 3045 nM
|
|
|
|
CP0858046
|
Trans-5-Chloro-N-[4-(6-chloro-3,3-difluoro-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C22H21Cl2F2N3O2
|
1
|
| 1 |
IC50 = 3124 nM
|
|
|
|
CP0902359
|
Trans-5-Chloro-2-methyl-N-[4-(3-methyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-cyclohexyl]-nicotinamide
Show/Hide
|
C22H25ClN4O2
|
1
|
| 1 |
IC50 = 3560 nM
|
|
|
|
CP0429711
|
US8835444, 3.6
Show/Hide
|
C23H26ClN5O
|
1
|
| 1 |
IC50 = 3737 nM
|
|
|
|
CP0911674
|
Trans-5-chloro-N-[4-(3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl nicotinamide
Show/Hide
|
C24H28ClN3O2
|
1
|
| 1 |
IC50 = 3795 nM
|
|
|
|
CP0862005
|
Trans-2-Chloro-N-[4-(6-fluoro-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-bcnzamide
Show/Hide
|
C23H21ClF4N2O2
|
1
|
| 1 |
IC50 = 3874 nM
|
|
|
|
CP0860149
|
Trans-2-chloro-N-[4-(3,3-dimethyl-2-oxo-2,3-dihydro-pyrrolo[2,3-b]pyridin-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide
Show/Hide
|
C23H25ClFN3O2
|
1
|
| 1 |
IC50 = 4587 nM
|
|
|
|
CP0911855
|
Trans-5-Chloro-N-[4-(6-chloro-3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl-nicotinamide
Show/Hide
|
C24H27Cl2N3O2
|
1
|
| 1 |
IC50 = 4620 nM
|
|
|
|
CP0441516
|
US8835444, 3.3
Show/Hide
|
C24H26ClFN4O
|
1
|
| 1 |
IC50 = 4630 nM
|
|
|
|
CP0871599
|
Trans-5-Chloro-2-methyl-N-[4-(3,3,4-trimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-nicotinamide
Show/Hide
|
C25H30ClN3O2
|
1
|
| 1 |
IC50 = 4810 nM
|
|
|
|
CP0416315
|
US8835444, 5.21
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|
C19H20Cl2F3N3O2
|
1
|
| 1 |
IC50 = 4847 nM
|
|
|
|
CP0879022
|
US8835444, 1.1
Show/Hide
|
C20H28ClN5O
|
1
|
| 1 |
IC50 = 4878 nM
|
|
|
|
CP0425467
|
US8835444, 2.4
Show/Hide
|
C24H27ClN4O
|
1
|
| 1 |
IC50 = 4943 nM
|
|
|
|
CP0456085
|
9-chloro-6-[(1R)-1-(difluoromethoxy)-2,2,2-trifluoroethyl]-1-(2-methoxy-4,6-dimethylpyrimidin-5-yl)-3,4-dihydro-2H-pyrimido[1,2-a]benzimidazole
Show/Hide
|
C20H19ClF5N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
