Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Trans-2-Chloro-N-[4-(7-methoxy-3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide
    Show/Hide
 PubChem ID
SID: 125006543
Canonical SMILES
COc1cccc2c1N(C[C@H]1CC[C@H](NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC1)C(=O)C2(C)C
    Show/Hide
Compound Formula C26H28ClF3N2O3
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 2
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
Q13324
Gene Name
CRHR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1685 nM
   TI
   LI
   LO
   TS