Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Trans-5-chloro-N-[4-(3,3-dimethyl-2-oxo-2,3-dihydro-indol-1-ylmethyl)-cyclohexyl]-2-methyl nicotinamide
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 PubChem ID
SID: 125006404
Canonical SMILES
Cc1ncc(Cl)cc1C(=O)N[C@H]1CC[C@H](CN2C(=O)C(C)(C)c3ccccc32)CC1
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Compound Formula C24H28ClN3O2
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 2
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
Q13324
Gene Name
CRHR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3795 nM
   TI
   LI
   LO
   TS