Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT02562 , Membrane primary amine oxidase
Gene Name AOC3
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q16853
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT02562
 
Compound ID Compound Name Compound Formula
CP0943875
[2-fluoro-3-(2-morpholinopyrimidin-5-yl)phenyl]methyl-N-carbamimidoylcarbamate hydrochloride
   Show/Hide
C17H20ClFN6O3
 1
1
IC50 = 9.2 nM
   TI
   LI
   LO
   TS
CP0956592
3-[4-(Pyridin-4-yl)piperazin-1-yl]benzyl-N-carbamimidoylcarbamate trihydrochloride
   Show/Hide
C18H25Cl3N6O2
 1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0904633
2-Fluoro-3-[4-(pyridin-3-yl)piperazin-1-yl]benzyl-N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C22H27FN6O8
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0658461
N-[4-(2-{4-[(2-Amino-1H-imidazol-4-yl)methyl]phenyl}ethyl)thiazol-2-yl]acetamide hydrochloride
   Show/Hide
C17H20ClN5OS
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0049270
2-phenylethylhydrazine
   Show/Hide
C8H12N2
 1
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
CP0456931
N-[4-[2-[4-(diaminomethylideneamino)phenyl]ethyl]-5-[(4-methylsulfonylphenyl)methyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C22H25N5O3S2
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0860492
2-Fluoro-3-[3-(pyridin-3-yloxy)azetidin-1-yl]benzyl-N-carbamimidoylcarbamate hemi(2R,3R)-tartrate
   Show/Hide
C38H42F2N10O12
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0954479
4-{4-[5-(3-{[Glycyl(methyl)amino]methyl}phenyl)pyrimidin-2-yl]piperazin-1-yl}benzoic acid dihydrochloride
   Show/Hide
C25H30Cl2N6O3
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0905705
2-Fluoro-3-{3-[(6-methylpyridin-3-yl)oxy]azetidin-1-yl}benzyl-N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C22H26FN5O9
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0904605
3-Chloro-4-{4-[5-(3-{[glycyl(methyl)amino]methyl}phenyl)pyrimidin-2-yl]piperazin-1-yl}benzoic acid dihydrochloride
   Show/Hide
C25H29Cl3N6O3
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0473477
2-hydrazinyl-1-(4-methoxyphenyl)ethanol
   Show/Hide
C9H14N2O2
 1
1
IC50 = 28.84 nM
   TI
   LI
   LO
   TS
CP0948428
2-amino-N-methyl-N-(3-(2-morpholinopyrimidin-5-yl)benzyl)acetamide (2R,3R)-tartrate
   Show/Hide
C22H29N5O8
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0965396
3-[4-(Pyridin-3-yl)piperazin-1-yl]benzyl-N-carbamimidoylcarbamate trihydrochloride
   Show/Hide
C18H25Cl3N6O2
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0915844
N-Methyl-N-{3-[2-(morpholin-4-yl)pyrimidin-5-yl]benzyl}glycinamide (2R,3R)-tartrate
   Show/Hide
C22H29N5O8
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0901202
N-{4-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-5-[4-(methylsulfonyl)phenyl]-1,3-thiazol-2-yl}acetamidehydrochloride
   Show/Hide
C21H24ClN5O3S2
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0465625
N-[4-[2-[4-(diaminomethylideneamino)phenyl]ethyl]-5-[(3-methylsulfonylphenyl)methyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C22H25N5O3S2
 1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0466202
(R)-2-Hydrazino-1-phenylethanol
   Show/Hide
C8H12N2O
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0960957
2-Fluoro-3-{3-[(2-methylpyridin-3-yl)oxy]azetidin-1-yl}benzyl-N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C22H26FN5O9
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0965533
2-Fluoro-3-[4-(pyridin-3-yloxy)piperidin-1-yl]benzyl-N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C23H28FN5O9
 1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0857302
N-(3-{2-[4-(2-Hydroxyethyl)piperidin-1-yl]pyrimidin-5-yl}benzyl)-N-methylglycinamide (2R,3R)-tartrate
   Show/Hide
C25H35N5O8
 1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0947025
[3-(2-morpholinopyrimidin-5-yl)phenyl]methyl N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C21H26N6O9
 1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
CP0492979
2-hydrazinyl-1-(3-methoxyphenyl)ethanol
   Show/Hide
C9H14N2O2
 1
1
IC50 = 52.48 nM
   TI
   LI
   LO
   TS
CP0900912
N-{4-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-5-[4-(aminosulfonyl)benzyl]-1,3-thiazol-2-yl}acetamidehydrochloride
   Show/Hide
C21H25ClN6O3S2
 1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
CP0956589
N-Carbamimidoyl-2-(3-{2-[2-(morpholin-4-yl)pyrimidin-5-yl]ethyl}phenyl)acetamide hemi(2R,3R)-tartrate
   Show/Hide
C42H54N12O10
 1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
CP0946801
N-Methyl-N-{3-[6-(morpholin-4-yl)pyridin-3-yl]benzyl}glycinamide (2R,3R)-tartrate
   Show/Hide
C23H30N4O8
 1
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
CP0862694
N-Carbamimidoyl-2-{3-[2-(morpholin-4-yl)pyrimidin-5-yl]phenyl}acetamide (2R,3R)-tartrate
   Show/Hide
C21H26N6O8
 1
1
IC50 = 56 nM
   TI
   LI
   LO
   TS
CP0522093
2-phenylpropylhydrazine
   Show/Hide
C9H14N2
 1
1
IC50 = 58.88 nM
   TI
   LI
   LO
   TS
CP0533344
1-[2-(4-methoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C10H16N2O
 1
1
IC50 = 60.26 nM
   TI
   LI
   LO
   TS
CP0912480
2-Hydrazino-1-phenylethanol
   Show/Hide
C8H12N2O
 1
1
IC50 = 64.57 nM
   TI
   LI
   LO
   TS
CP0488637
1-[2-(4-chlorophenyl)ethyl]-1-methylhydrazine
   Show/Hide
C9H13ClN2
 1
1
IC50 = 70.79 nM
   TI
   LI
   LO
   TS
CP0956590
2,4-Difluoro-3-[2-(morpholin-4-yl)pyrimidin-5-yl]benzylcarbamimidoylcarbamate hemi(2R,3R)-tartrate
   Show/Hide
C38H42F4N12O12
 1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
CP0473478
1-ethyl-1-[2-(4-methoxyphenyl)ethyl]hydrazine
   Show/Hide
C11H18N2O
 1
1
IC50 = 79.43 nM
   TI
   LI
   LO
   TS
CP0967423
N-(3'-{[Glycyl(methyl)amino]methyl}biphenyl-4-yl)morpholine-4-carboxamide ethanedioate
   Show/Hide
C23H28N4O7
 1
1
IC50 = 83 nM
   TI
   LI
   LO
   TS
CP0488636
1-[2-(3-methoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C10H16N2O
 1
1
IC50 = 89.13 nM
   TI
   LI
   LO
   TS
CP0513558
1-[2-(2-fluorophenyl)ethyl]-1-methylhydrazine
   Show/Hide
C9H13FN2
 1
1
IC50 = 91.2 nM
   TI
   LI
   LO
   TS
CP0915494
[4-fluoro-3-(2-morpholinopyrimidin-5-yl)phenyl]methyl-N-carbamimidoylcarbamate dihydrochloride
   Show/Hide
C17H21Cl2FN6O3
 1
1
IC50 = 99 nM
   TI
   LI
   LO
   TS
CP0492983
1-[2-(4-fluorophenyl)ethyl]-1-methylhydrazine
   Show/Hide
C9H13FN2
 1
1
IC50 = 109.65 nM
   TI
   LI
   LO
   TS
CP0492984
1-methyl-1-(2-phenylethyl)hydrazine
   Show/Hide
C9H14N2
 1
1
IC50 = 109.65 nM
   TI
   LI
   LO
   TS
CP0904632
3-[4-(Tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzyl-N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C22H33N5O9
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0406047
1-[2-(3-chlorophenyl)ethyl]-1-methylhydrazine
   Show/Hide
C9H13ClN2
 1
1
IC50 = 120.23 nM
   TI
   LI
   LO
   TS
CP0954478
N-{3-[2-(4-Hydroxypiperidin-1-yl)pyrimidin-5-yl]benzyl}-N-methylglycinamide (2R,3R)-tartrate
   Show/Hide
C23H31N5O8
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0860491
3-[4-(Pyridin-2-yl)piperazin-1-yl]benzyl-N-carbamimidoylcarbamate trihydrochloride
   Show/Hide
C18H25Cl3N6O2
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0964602
3-{1-[5-(3-{[Glycyl(methyl)amino]methyl}phenyl)pyrimidin-2-yl]piperidin-4-yl}propanoic acid dihydrochloride
   Show/Hide
C22H31Cl2N5O3
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0460357
(S)-2-Hydrazino-1-phenylethanol
   Show/Hide
C8H12N2O
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0900911
N-(4-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-5-{4-[(dimethylamino)sulfonyl]benzyl}-1,3-thiazol-2-yl)acetamide hydrochloride
   Show/Hide
C23H29ClN6O3S2
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0940284
N-(4-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-5-{2-[4-(methylsulfonyl)phenyl]ethyl}-1,3-thiazol-2-yl)acetamide hydrochloride
   Show/Hide
C23H28ClN5O3S2
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0956591
3-[4-(Morpholin-4-yl)piperidin-1-yl]benzyl-N-carbamimidoylcarbamate trihydrochloride
   Show/Hide
C18H30Cl3N5O3
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0509285
1-[2-(2-chlorophenyl)ethyl]-1-methylhydrazine
   Show/Hide
C9H13ClN2
 1
1
IC50 = 169.82 nM
   TI
   LI
   LO
   TS
CP0887128
N-(Biphenyl-3-ylmethyl)glycinamide hydrochloride
   Show/Hide
C15H17ClN2O
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0492981
1-ethyl-1-(2-phenylethyl)hydrazine
   Show/Hide
C10H16N2
 1
1
IC50 = 181.97 nM
   TI
   LI
   LO
   TS
CP0501967
2-[amino(methyl)amino]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanol
   Show/Hide
C11H16N2O3
 1
1
IC50 = 199.53 nM
   TI
   LI
   LO
   TS
CP0406044
2-[amino(methyl)amino]-1-phenylethanol
   Show/Hide
C9H14N2O
 1
1
IC50 = 208.93 nM
   TI
   LI
   LO
   TS
CP0900922
N-{4-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-5-benzyl-1,3-thiazol-2-yl}acetamide hydrochloride
   Show/Hide
C21H24ClN5OS
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0492973
2-[amino(methyl)amino]-1-(2,3,4-trimethoxyphenyl)ethanol
   Show/Hide
C12H20N2O4
 1
1
IC50 = 218.78 nM
   TI
   LI
   LO
   TS
CP0533335
1-(2-methoxy-2-naphthalen-2-ylethyl)-1-methylhydrazine
   Show/Hide
C14H18N2O
 1
1
IC50 = 229.09 nM
   TI
   LI
   LO
   TS
CP0200164
N-[4-[2-[4-(diaminomethylideneamino)phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C14H17N5OS
 1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CP0493610
1-methyl-1-(3-phenylpropyl)hydrazine
   Show/Hide
C10H16N2
 1
1
IC50 = 239.88 nM
   TI
   LI
   LO
   TS
CP0900663
N-[(4'-Chlorobiphenyl-3-yl)methyl]-N-methylglycinamide hydrochloride
   Show/Hide
C16H18Cl2N2O
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0541504
2-[[3-[2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidin-5-yl]phenyl]methyl-methylamino]acetamide;dihydrochloride
   Show/Hide
C19H27Cl2N5O2
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0911121
N-Methyl-N-{3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzyl}glycinamide dihydrochloride
   Show/Hide
C19H27Cl2N5O
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0406045
1-[2-(4-methoxyphenyl)ethyl]-1-(2-methylpropyl)hydrazine
   Show/Hide
C13H22N2O
 1
1
IC50 = 257.04 nM
   TI
   LI
   LO
   TS
CP0492969
(1R,2S)-2-[amino(methyl)amino]-1-phenylbutan-1-ol
   Show/Hide
C11H18N2O
 1
1
IC50 = 257.04 nM
   TI
   LI
   LO
   TS
CP0522092
(1R,2S)-2-[amino(methyl)amino]-1-phenylpentan-1-ol
   Show/Hide
C12H20N2O
 1
1
IC50 = 257.04 nM
   TI
   LI
   LO
   TS
CP0406043
2-[amino(methyl)amino]-1-(2-chlorophenyl)ethanol
   Show/Hide
C9H13ClN2O
 1
1
IC50 = 269.15 nM
   TI
   LI
   LO
   TS
CP0492968
1-benzyl-1-methylhydrazine
   Show/Hide
C8H12N2
 1
1
IC50 = 269.15 nM
   TI
   LI
   LO
   TS
CP0486828
(1R,2S)-2-(1-Methylhydrazino)-1,2-diphenylethanol
   Show/Hide
C15H18N2O
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0930280
N-({4'-[(Dimethylcarbamoyl)amino]biphenyl-3-yl}methyl)-N-methylglycinamide ethanedioate
   Show/Hide
C21H26N4O6
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0406042
2-[amino(methyl)amino]-1-(3-methoxyphenyl)ethanol
   Show/Hide
C10H16N2O2
 1
1
IC50 = 281.84 nM
   TI
   LI
   LO
   TS
CP0541499
2-[[3-[2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidin-5-yl]phenyl]methyl-methylamino]acetamide;dihydrochloride
   Show/Hide
C19H27Cl2N5O2
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0492976
2-[amino(methyl)amino]-1-(4-methoxyphenyl)ethanol
   Show/Hide
C10H16N2O2
 1
1
IC50 = 309.03 nM
   TI
   LI
   LO
   TS
CP0509283
2-[amino(methyl)amino]-1-(4-chlorophenyl)ethanol
   Show/Hide
C9H13ClN2O
 1
1
IC50 = 309.03 nM
   TI
   LI
   LO
   TS
CP0940898
Methyl 4-({2-(acetylamino)-4-[2-(4-{[amino(imino)methyl]amino}phenyl)ethyl]-1,3-thiazol-5-yl}methyl)benzoatehydrochloride
   Show/Hide
C23H26ClN5O3S
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0493609
2-[amino(methyl)amino]-1-(4-fluorophenyl)ethanol
   Show/Hide
C9H13FN2O
 1
1
IC50 = 323.59 nM
   TI
   LI
   LO
   TS
CP0509284
1-methyl-1-[2-(3,4,5-trimethoxyphenyl)ethyl]hydrazine
   Show/Hide
C12H20N2O3
 1
1
IC50 = 323.59 nM
   TI
   LI
   LO
   TS
CP0522091
1-[2-methoxy-2-(3-methylphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C11H18N2O
 1
1
IC50 = 323.59 nM
   TI
   LI
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   TS
CP0520902
(1S,2R)-2-(1-Methylhydrazino)-1,2-diphenylethanol
   Show/Hide
C15H18N2O
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0908166
N-{4-[4-(2-{[Amino(imino)methyl]amino}ethyl)phenyl]-1,3-thiazol-2-yl}acetamide hydrochloride
   Show/Hide
C14H18ClN5OS
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0897696
N-Methyl-N-{[4'-(4-methylpiperazin-1-yl)biphenyl-3-yl]methyl}glycinamide (2R,3R)-tartrate
   Show/Hide
C25H34N4O7
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0531259
1-methyl-1-[2-(2,3,4-trimethoxyphenyl)ethyl]hydrazine
   Show/Hide
C12H20N2O3
 1
1
IC50 = 331.13 nM
   TI
   LI
   LO
   TS
CP0906413
N-Methyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}glycinamide ethanedioate
   Show/Hide
C22H27N3O6
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0406093
1-[amino(methyl)amino]-2-(4-methoxyphenyl)propan-2-ol
   Show/Hide
C11H18N2O2
 1
1
IC50 = 346.74 nM
   TI
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CP0479553
(1R,2S)-2-[amino(methyl)amino]-1-phenylpropan-1-ol
   Show/Hide
C10H16N2O
 1
1
IC50 = 346.74 nM
   TI
   LI
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CP0492971
2-[amino(2-methylpropyl)amino]-1-phenylethanol
   Show/Hide
C12H20N2O
 1
1
IC50 = 346.74 nM
   TI
   LI
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   TS
CP0493611
1-[2-(2-methoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C10H16N2O
 1
1
IC50 = 346.74 nM
   TI
   LI
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   TS
CP0508013
1-[2-(3,4-dimethoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C11H18N2O2
 1
1
IC50 = 346.74 nM
   TI
   LI
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   TS
CP0492982
1-[2-(2,5-dimethoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C11H18N2O2
 1
1
IC50 = 371.54 nM
   TI
   LI
   LO
   TS
CP0492874
1-[2-(4-methoxyphenyl)-2-phenylmethoxyethyl]-1-methylhydrazine
   Show/Hide
C17H22N2O2
 1
1
IC50 = 389.05 nM
   TI
   LI
   LO
   TS
CP0857184
N-{1-[2-(4-Carbamimidamidophenyl)ethyl]-5-[4-(methylsulfonyl)phenyl]-1H-pyrazol-3-yl}acetamidehydrochloride
   Show/Hide
C21H25ClN6O3S
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0509282
1-(2-methoxy-2-naphthalen-1-ylethyl)-1-methylhydrazine
   Show/Hide
C14H18N2O
 1
1
IC50 = 398.11 nM
   TI
   LI
   LO
   TS
CP0860490
[2-fluoro-3-(4-methyl-2-morpholino-pyrimidin-5-yl)phenyl]methyl N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C22H27FN6O9
 1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
CP0513555
1-[2-methoxy-2-(3-methoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C11H18N2O2
 1
1
IC50 = 407.38 nM
   TI
   LI
   LO
   TS
CP0513557
1-[2-(3-chlorophenyl)-2-methoxyethyl]-1-methylhydrazine
   Show/Hide
C10H15ClN2O
 1
1
IC50 = 407.38 nM
   TI
   LI
   LO
   TS
CP0903574
[2-methyl-3-(2-morpholinopyrimidin-5-yl)phenyl]methyl-N-carbamimidoylcarbamate (2R,3R)-tartrate
   Show/Hide
C22H28N6O9
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0520877
1-[2-methoxy-2-(4-methoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C11H18N2O2
 1
1
IC50 = 416.87 nM
   TI
   LI
   LO
   TS
CP0917664
N-Methyl-N-{[4'-(morpholin-4-ylcarbonyl)biphenyl-3-yl]methyl}glycinamide (2R,3R)-tartrate
   Show/Hide
C25H31N3O9
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0406041
2-[amino(methyl)amino]-1-naphthalen-2-ylethanol
   Show/Hide
C13H16N2O
 1
1
IC50 = 426.58 nM
   TI
   LI
   LO
   TS
CP0513556
1-[2-(4-chlorophenyl)-2-methoxyethyl]-1-methylhydrazine
   Show/Hide
C10H15ClN2O
 1
1
IC50 = 426.58 nM
   TI
   LI
   LO
   TS
CP0406046
1-(2-methylpropyl)-1-(2-phenylethyl)hydrazine
   Show/Hide
C12H20N2
 1
1
IC50 = 436.52 nM
   TI
   LI
   LO
   TS
CP0520879
1-[2-(3-fluorophenyl)-2-methoxyethyl]-1-methylhydrazine
   Show/Hide
C10H15FN2O
 1
1
IC50 = 436.52 nM
   TI
   LI
   LO
   TS
CP0958224
N-[(4'-Acetamidobiphenyl-3-yl)methyl]-N-methylglycinamide hydrochloride
   Show/Hide
C18H22ClN3O2
 1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CP0502138
1-methyl-1-(2-phenylpropyl)hydrazine
   Show/Hide
C10H16N2
 1
1
IC50 = 467.74 nM
   TI
   LI
   LO
   TS
CP0899707
N-({4'-[(Diethylamino)methyl]biphenyl-3-yl}methyl)-Nmethylglycinamide dihydrochloride
   Show/Hide
C21H31Cl2N3O
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0431910
N-[4-[2-[4-(diaminomethylideneamino)phenyl]ethyl]-1,3-thiazol-2-yl]-2-methylpropanamide
   Show/Hide
C16H21N5OS
 1
1
IC50 = 520 nM
   TI
   LI
   LO
   TS
CP0878529
3-Carbamimidoyl-1-methyl-1-{3-[2-(morpholin-4-yl)pyrimidin-5-yl]benzyl}urea (2R,3R)-tartrate
   Show/Hide
C22H29N7O8
 1
1
IC50 = 530 nM
   TI
   LI
   LO
   TS
CP0962609
N,N-Diethyl-3'-{[glycyl(methyl)amino]methyl}biphenyl-4-carboxamide ethanedioate
   Show/Hide
C23H29N3O6
 1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
CP0473476
2-[amino(methyl)amino]-2-methyl-1-phenylpropan-1-ol
   Show/Hide
C11H18N2O
 1
1
IC50 = 562.34 nM
   TI
   LI
   LO
   TS
CP0520878
1-[2-(4-fluorophenyl)-2-methoxyethyl]-1-methylhydrazine
   Show/Hide
C10H15FN2O
 1
1
IC50 = 575.44 nM
   TI
   LI
   LO
   TS
CP0860489
[2-chloro-3-(2-morpholinopyrimidin-5-yl)phenyl]methyl N-carbamimidoylcarbamate dihydrochloride
   Show/Hide
C17H21Cl3N6O3
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0952405
N-Ethyl-3'-{[glycyl(methyl)amino]methyl}biphenyl-4-carboxamide hydrochloride
   Show/Hide
C19H24ClN3O2
 1
1
IC50 = 610 nM
   TI
   LI
   LO
   TS
CP0473475
1-[2-methoxy-2-(2,3,4-trimethoxyphenyl)ethyl]-1-methylhydrazine
   Show/Hide
C13H22N2O4
 1
1
IC50 = 630.96 nM
   TI
   LI
   LO
   TS
CP0462379
N-[4-[2-[4-[(N'-ethylcarbamimidoyl)amino]phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C16H21N5OS
 1
1
IC50 = 680 nM
   TI
   LI
   LO
   TS
CP0522738
N-[4-[2-[4-(aminomethylideneamino)phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C14H16N4OS
 1
1
IC50 = 730 nM
   TI
   LI
   LO
   TS
CP0573219
2-amino-N-methyl-N-[(3-phenylphenyl)methyl]acetamide
   Show/Hide
C16H18N2O
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0494328
(1R,2R)-2-(1-Methylhydrazino)-1,2-diphenylethanol
   Show/Hide
C15H18N2O
 1
1
IC50 = 1060 nM
   TI
   LI
   LO
   TS
CP0505475
N-[4-[2-[4-[(N'-propan-2-ylcarbamimidoyl)amino]phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C17H23N5OS
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0908167
Methyl N-{4-[2-(2-acetamido-1,3-thiazol-4-yl)ethyl]phenyl}carbamimidothioate hydroiodide
   Show/Hide
C15H19IN4OS2
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0386177
N-[4-[2-[4-(diaminomethylideneamino)phenyl]ethyl]-5-[(4-methylsulfanylphenyl)methyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C22H25N5OS2
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0513246
(1S,2S)-2-(1-Methylhydrazino)-1,2-diphenylethanol
   Show/Hide
C15H18N2O
 1
1
IC50 = 1180 nM
   TI
   LI
   LO
   TS
CP0478597
2-Hydrazino-1-phenylpentanol
   Show/Hide
C11H18N2O
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0528271
[5-(3-methylsulfonyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C17H16N2O4S3
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0967422
N-[(3'-Chlorobiphenyl-3-yl)methyl]-N-methylglycinamide ethanedioate
   Show/Hide
C18H19ClN2O5
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0439960
[5-[3-(4-methylphenyl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C18H18N2O4S3
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0867965
N-Methyl-N-({5-[4-(morpholin-4-yl)phenyl]pyridin-3-yl}methyl)glycinamide (2R,3R)-tartrate
   Show/Hide
C23H30N4O8
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0930370
3'-{[Glycyl(methyl)amino]methyl}biphenyl-4-carboxamide hydrochloride
   Show/Hide
C17H20ClN3O2
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0904616
1-[5-(3-{[Glycyl(methyl)amino]methyl}phenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid dihydrochloride
   Show/Hide
C20H27Cl2N5O3
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0901840
N-Methyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}ethane-1,2-diamine (2R,3R)-tartrate
   Show/Hide
C24H33N3O7
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0962610
2-Amino-1-{5-[4-(morpholin-4-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}ethanone hydrochloride
   Show/Hide
C20H24ClN3O2
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0852596
N-Methyl-N-({6-[4-(morpholin-4-yl)phenyl]pyridin-2-yl}methyl)glycinamide dihydrochloride
   Show/Hide
C19H26Cl2N4O2
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0456932
N-[1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrazol-3-yl]acetamide
   Show/Hide
C18H16FN3O3S
 1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CP0949294
N-[4-(2-{4-[(2-Amino-1H-imidazol-4-yl)ethyl]phenyl}ethyl)thiazol-2-yl]acetamide hydrochloride
   Show/Hide
C18H22ClN5OS
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0492980
1-ethyl-1-[2-(3,4,5-trimethoxyphenyl)ethyl]hydrazine
   Show/Hide
C13H22N2O3
 1
1
IC50 = 2238.72 nM
   TI
   LI
   LO
   TS
CP0433342
N-[4-[2-[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C16H19N5OS
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0967412
N-{[4'-(Dimethylamino)biphenyl-3-yl]methyl}-N-methylglycinamide ethanedioate
   Show/Hide
C20H25N3O5
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0431913
N-[4-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C16H18N4OS2
 1
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0349042
[5-(3-ethyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C18H18N2O2S2
 1
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS
CP0930281
N-Methyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}-beta-alaninamide (2R,3R)-tartrate
   Show/Hide
C25H33N3O8
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0014376
1H-1,3-benzodiazol-2-amine
   Show/Hide
C7H7N3
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0923138
N-[(2'-Chlorobiphenyl-3-yl)methyl]-N-methylglycinamide hydrochloride
   Show/Hide
C16H18Cl2N2O
 1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CP0431911
N-[4-[2-[4-(2-aminoethyl)phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C15H19N3OS
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0860488
N-(4-{2-[2-(Morpholin-4-yl)pyrimidin-5-yl]ethyl}phenyl)guanidine dihydrochloride
   Show/Hide
C17H24Cl2N6O
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0920792
N-{4-[3-(4-{[Amino(imino)methyl]amino}phenyl)propyl]-1,3-thiazol-2-yl}acetamide hydrochloride
   Show/Hide
C15H20ClN5OS
 1
1
IC50 = 8800 nM
   TI
   LI
   LO
   TS
CP0932776
N-{5-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-1,3-thiazol-2-yl}acetamide hydrochloride
   Show/Hide
C14H18ClN5OS
 1
1
IC50 = 9600 nM
   TI
   LI
   LO
   TS
CP0431912
N-[4-[2-[4-(carbamothioylamino)phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C14H16N4OS2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0943874
N-[2-(3-{2-[2-(Morpholin-4-yl)pyrimidin-5-yl]ethyl}phenyl)ethyl]guanidine dihydrochloride
   Show/Hide
C19H28Cl2N6O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0943880
N-(3-{2-[2-(Morpholin-4-yl)pyrimidin-5-yl]ethyl}phenyl)guanidine dihydrochloride
   Show/Hide
C17H24Cl2N6O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0851035
N-{4-[2-(4-{[Amino(imino)methyl]amino}phenyl)ethyl]-1,3-thiazol-2-yl}benzamide hydrochloride
   Show/Hide
C19H20ClN5OS
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0857664
N-(4-{2-[4-(2-Amino-1H-imidazol-4-yl)phenyl]ethyl}thiazol-2-yl)acetamide hydrochloride
   Show/Hide
C16H18ClN5OS
 1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0384458
[5-[3-(1-methylpyrazol-4-yl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C15H16N4O4S3
 1
1
IC50 = 13300 nM
   TI
   LI
   LO
   TS
CP0957621
3'-{[Glycyl(methyl)amino]methyl}biphenyl-4-carboxylicacid hydrochloride
   Show/Hide
C17H19ClN2O3
 1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0871650
N-{3-[2-(4-Carbamimidamidophenyl)ethyl]phenyl}acetamide hydrochloride
   Show/Hide
C17H21ClN4O
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0893965
N-{4-[2-(4-Carbamimidamidophenyl)ethyl]phenyl}acetamide hydrochloride
   Show/Hide
C17H21ClN4O
 1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0384459
[5-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C16H18N4O2S2
 1
1
IC50 = 19600 nM
   TI
   LI
   LO
   TS
CP0904144
1-{4-[2-(2-Amino-1,3-thiazol-4-yl)ethyl]phenyl}guanidine dihydrochloride
   Show/Hide
C12H17Cl2N5S
 1
1
IC50 = 22000 nM
   TI
   LI
   LO
   TS
CP0413873
5-benzyl-1H-imidazol-2-amine
   Show/Hide
C10H11N3
 1
1
IC50 = 32000 nM
   TI
   LI
   LO
   TS
CP0559457
[5-[3-fluoro-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C14H13FN4O2S2
 1
1
IC50 = 36300 nM
   TI
   LI
   LO
   TS
CP0920136
N-[4-(4-Carbamimidamidobenzyl)-1,3-thiazol-2-yl]acetamide hydrochloride
   Show/Hide
C13H16ClN5OS
 1
1
IC50 = 42000 nM
   TI
   LI
   LO
   TS
CP0528276
(5-naphthalen-2-ylsulfonyl-1,3-thiazol-2-yl)methanamine
   Show/Hide
C14H12N2O2S2
 1
1
IC50 = 47100 nM
   TI
   LI
   LO
   TS
CP0478596
(1R*,2S*)-2-Hydrazino-1,2-diphenylethanol
   Show/Hide
C14H16N2O
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0946353
1H-indol-2-amine hydrochloride
   Show/Hide
C8H9ClN2
 1
1
IC50 = 74000 nM
   TI
   LI
   LO
   TS
CP0426810
[4-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
   Show/Hide
C16H18N4O2S2
 1
1
IC50 = 74300 nM
   TI
   LI
   LO
   TS
CP0522739
N-[4-[2-[4-[[amino(dimethylamino)methylidene]amino]phenyl]ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C16H21N5OS
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0522740
N-[4-[2-(4-aminophenyl)ethyl]-1,3-thiazol-2-yl]acetamide
   Show/Hide
C13H15N3OS
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0057720
1,3-benzothiazol-2-amine
   Show/Hide
C7H6N2S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0142371
1H-1,3-benzodiazole
   Show/Hide
C7H6N2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0222047
1-phenylguanidine
   Show/Hide
C7H9N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0245992
quinazolin-2-amine
   Show/Hide
C8H7N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0389020
5-(2-phenylethyl)-1H-imidazol-2-amine
   Show/Hide
C11H13N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0418891
6-methyl-1H-benzimidazol-2-amine
   Show/Hide
C8H9N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0418892
4-methyl-1H-benzimidazol-2-amine
   Show/Hide
C8H9N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0509177
5-phenyl-1H-imidazol-2-amine
   Show/Hide
C9H9N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0545959
1-methyl-1H-1,3-benzodiazol-2-amine
   Show/Hide
C8H9N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0755319
(1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride
   Show/Hide
C8H11Cl2N3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0857663
1-Phenyl-imidazolidin-2-ylideneamine hydrobromide
   Show/Hide
C9H12BrN3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0906015
N-phenyl-4,5-dihydro-1H-imidazol-2-amine hydrochloride
   Show/Hide
C9H12ClN3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0946352
1H-imidazol-2-amine hemisulfate
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C3H7N3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0887127
N,N2,N2-Trimethyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}glycinamide (2R,3R)-tartrate
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C26H35N3O8
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0901839
N,N2-Dimethyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}glycinamide (2R,3R)-tartrate
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C25H33N3O8
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0902848
N,2-Dimethyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}alaninamide (2R,3R)-tartrate
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C26H35N3O8
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0919349
N-Isopropyl-N-{[4'-(morpholin-4-yl)biphenyl-3-yl]methyl}glycinamide (2R,3R)-tartrate
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C26H35N3O8
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0952406
N-(2-Aminoethyl)-N-methyl-4'-(morpholin-4-yl)biphenyl-3-carboxamide (2R,3R)-tartrate
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C24H31N3O8
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0421556
[4-(3-methylsulfonyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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C17H16N2O4S3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0426167
[4-[3-(1-methylpyrazol-4-yl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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C15H16N4O4S3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS