General Information of the Compound
Compound ID
CP0899707
Compound Name
N-({4'-[(Diethylamino)methyl]biphenyl-3-yl}methyl)-Nmethylglycinamide dihydrochloride
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Structure
Formula
C21H31Cl2N3O
Molecular Weight
412.405
Canonical SMILES
CCN(CC)Cc1ccc(-c2cccc(CN(C)C(=O)CN)c2)cc1.Cl.Cl
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InChI
InChI=1S/C21H29N3O.2ClH/c1-4-24(5-2)16-17-9-11-19(12-10-17)20-8-6-7-18(13-20)15-23(3)21(25)14-22;;/h6-13H,4-5,14-16,22H2,1-3H3;2*1H
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InChIKey
QWENYXCBKYCQOM-UHFFFAOYSA-N
Physicochemical Property
logP
3.9561
Rotatable Bonds
8
Heavy Atom Count
27
Polar Areas
49.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 134138777
ChEMBL ID
CHEMBL3932184
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02562, Membrane primary amine oxidase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 480 nM
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