| Compound ID |
Compound Name |
Compound Formula |
|
CP0372367
|
3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)propanoic acid
Show/Hide
|
C22H21F3N2O4
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0381566
|
4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylbenzoic acid
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381831
|
3-(4-(5-(3-cyano-4-(2,2,2-trifluoroethoxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H16F3N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381832
|
3-(4-(5-(3-cyano-4-(1,1,1-trifluoropropan-2-yloxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H18F3N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381847
|
3-(4-(5-(4-methoxy-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C20H17F3N2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381848
|
3-(4-(5-(4-ethoxy-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H19F3N2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0390634
|
3-(4-(5-(5-chloro-6-(1,1,1-trifluoropropan-2-yloxy)pyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C20H17ClF3N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0390653
|
3-(4-(5-(4-isopropoxy-3-methylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H24N2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0390654
|
3-(4-(5-(3-fluoro-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21FN2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0390655
|
2-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)acetic acid
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394068
|
3-(4-(5-(6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C20H21N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394070
|
3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H23N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394073
|
3-(4-(5-(5-butylpyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H23N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394075
|
3-(4-(5-(4-(S)-sec-butoxy-3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394078
|
3-(4-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-3-yl}-3-methylphenyl)propanoic acid
Show/Hide
|
C22H21N3O4
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0394080
|
3-(4-(5-(4-isopropoxy-3-methoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H24N2O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394082
|
3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0403320
|
3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C20H20ClN3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0408158
|
5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole
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|
C21H22N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0408502
|
3-(4-(5-(5-(1,1-difluoro-2-methylpropyl)pyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21F2N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0408509
|
3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21ClN2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0408513
|
4-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)butanoic acid
Show/Hide
|
C25H28N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421165
|
3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H23N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421194
|
6-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)hexanoic acid
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0421315
|
3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H15F6N3O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0467328
|
3-(4-(5-(3-bromo-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21BrN2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0377161
|
3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)propanoic acid
Show/Hide
|
C23H31NO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0389617
|
(2S)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]-methylamino]-4-(dimethylamino)butanoic acid
Show/Hide
|
C30H36ClN3O5S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0387947
|
3-[2-ethyl-6-methyl-4-[5-[(2S,4R)-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-dien-7-yl]-1,2,4-oxadiazol-3-yl]phenyl]propanoic acid
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381087
|
3-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]propanoic acid
Show/Hide
|
C22H19NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0388429
|
4-[[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid
Show/Hide
|
C27H21NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0388439
|
5-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]pentanoic acid
Show/Hide
|
C24H23NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0388447
|
4-[(7-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]butanoic acid
Show/Hide
|
C23H21NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0414869
|
1-[(5-naphthalen-2-yl-1-benzothiophen-2-yl)methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H19NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0464445
|
4-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]butanoic acid
Show/Hide
|
C23H21NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0464446
|
2-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]acetic acid
Show/Hide
|
C21H17NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0014534
|
(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Show/Hide
|
C18H38NO5P
|
2
|
| 1 |
IC50 = 0.23 nM
|
|
|
| 2 |
IC50 = 0.35 nM
|
|
|
|
CP0559221
|
1-(3,5-dichlorophenyl)-3-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]urea
Show/Hide
|
C19H19Cl2N5O
|
3
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
| 3 |
IC50 = 3200 nM
|
|
|
|
CP0544160
|
1-(2-chloro-6-ethoxypyridin-4-yl)-3-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]urea
Show/Hide
|
C20H23ClN6O2
|
3
|
| 1 |
IC50 = 0.32 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
| 3 |
IC50 = 4700 nM
|
|
|
|
CP0551199
|
5,6-dichloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]-1H-benzimidazol-2-amine
Show/Hide
|
C19H18Cl2N6
|
3
|
| 1 |
IC50 = 0.43 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
| 3 |
IC50 = 2800 nM
|
|
|
|
CP0551200
|
4,6-dichloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]-1H-indole-2-carboxamide
Show/Hide
|
C21H19Cl2N5O
|
3
|
| 1 |
IC50 = 0.61 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
| 3 |
IC50 = 3000 nM
|
|
|
|
CP0047332
|
[2-azaniumyl-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] hydrogen phosphate
Show/Hide
|
C19H34NO5P
|
2
|
| 1 |
IC50 = 0.77 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0533873
|
1-(2,6-dichloropyridin-4-yl)-3-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]urea
Show/Hide
|
C18H18Cl2N6O
|
3
|
| 1 |
IC50 = 0.77 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
| 3 |
IC50 = 3500 nM
|
|
|
|
CP0531193
|
1-(2,6-dichloropyridin-4-yl)-3-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]amino]urea
Show/Hide
|
C17H17Cl2N7O
|
3
|
| 1 |
IC50 = 0.8 nM
|
|
|
| 2 |
IC50 > 23000 nM
|
|
|
| 3 |
IC50 > 1400 nM
|
|
|
|
CP0544159
|
4,6-dichloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C20H18Cl2N6O
|
3
|
| 1 |
IC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 890 nM
|
|
|
| 3 |
IC50 = 2800 nM
|
|
|
|
CP0409297
|
[2-amino-4-(4-octylphenyl)butyl] dihydrogen phosphate
Show/Hide
|
C18H32NO4P
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0559219
|
ethyl 6-[2-[(2,6-dichloropyridin-4-yl)carbamoyl]hydrazinyl]-4-methylpyridine-2-carboxylate
Show/Hide
|
C15H15Cl2N5O3
|
3
|
| 1 |
IC50 = 2.1 nM
|
|
|
| 2 |
IC50 = 760 nM
|
|
|
| 3 |
IC50 > 23000 nM
|
|
|
|
CP0546380
|
6-chloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]-4-ethoxy-1H-imidazo[4,5-c]pyridin-2-amine
Show/Hide
|
C20H22ClN7O
|
3
|
| 1 |
IC50 = 2.25 nM
|
|
|
| 2 |
IC50 = 33 nM
|
|
|
| 3 |
IC50 = 4200 nM
|
|
|
|
CP0417340
|
US8975409, Example 9
Show/Hide
|
C32H37FN2O6
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0548817
|
US8975409, Example 13
Show/Hide
|
C34H39FN2O6
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0557975
|
1-(2,6-dichloropyridin-4-yl)-3-[[4-methyl-6-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]urea
Show/Hide
|
C16H15Cl2N7O
|
3
|
| 1 |
IC50 = 3.1 nM
|
|
|
| 2 |
IC50 > 23000 nM
|
|
|
| 3 |
IC50 > 2100 nM
|
|
|
|
CP0549991
|
(2R)-2-[4-[[6-chloro-5-(cyclopropylmethoxy)indazol-2-yl]methyl]-1-oxophthalazin-2-yl]propanoic acid
Show/Hide
|
C23H21ClN4O4
|
2
|
| 1 |
IC50 = 3.2 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0576517
|
(2S)-2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]propanoic acid
Show/Hide
|
C23H21ClN4O4
|
2
|
| 1 |
IC50 = 3.2 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0422527
|
US8975409, Example 38
Show/Hide
|
C33H37FN2O7
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0546379
|
1-(2,6-dichloropyridin-4-yl)-3-[[4-methyl-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]urea
Show/Hide
|
C16H15Cl2N7O
|
3
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 2600 nM
|
|
|
| 3 |
IC50 > 23000 nM
|
|
|
|
CP0575747
|
2-[1-[[6-(cyclopropylmethoxy)-7-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]propanoic acid
Show/Hide
|
C24H21F3N4O4
|
2
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 51 nM
|
|
|
|
CP0489014
|
2-chloro-4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]benzoic acid
Show/Hide
|
C29H30ClFN2O6
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0413800
|
4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]benzoic acid
Show/Hide
|
C29H31FN2O6
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0863137
|
[(1S,3R)-3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0486509
|
US8975409, Example 15(6)
Show/Hide
|
C36H44FN3O6
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0539630
|
US8975409, Example 19
Show/Hide
|
C30H33FN2O6
|
2
|
| 1 |
IC50 = 5.2 nM
|
|
|
| 2 |
IC50 = 9.4 nM
|
|
|
|
CP0548342
|
1-(2,6-dichloropyridin-4-yl)-3-[[5-(dimethylamino)-4-methylpyridin-2-yl]amino]urea
Show/Hide
|
C14H16Cl2N6O
|
3
|
| 1 |
IC50 = 5.3 nM
|
|
|
| 2 |
IC50 = 3600 nM
|
|
|
| 3 |
IC50 > 23000 nM
|
|
|
|
CP0534011
|
2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]butanoic acid
Show/Hide
|
C24H23ClN4O4
|
2
|
| 1 |
IC50 = 5.6 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
|
CP0532870
|
2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]propanoic acid
Show/Hide
|
C23H21ClN4O4
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 31 nM
|
|
|
|
CP0395995
|
US8975409, Example 9(3)
Show/Hide
|
C31H26F2N2O6
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0422753
|
1-(2,6-dichloropyridin-4-yl)-3-[[6-(4-fluorophenyl)-4-methylpyridin-2-yl]amino]urea
Show/Hide
|
C18H14Cl2FN5O
|
3
|
| 1 |
IC50 = 6.2 nM
|
|
|
| 2 |
IC50 = 1300 nM
|
|
|
| 3 |
IC50 > 23000 nM
|
|
|
|
CP0545040
|
1-[4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]phenyl]cyclopropane-1-carboxylic acid
Show/Hide
|
C32H35FN2O6
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0576516
|
2-[4-[[5-(cyclopropylmethoxy)-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C23H19F3N4O4
|
2
|
| 1 |
IC50 = 6.6 nM
|
|
|
| 2 |
IC50 = 67 nM
|
|
|
|
CP0474711
|
US8975409, Example 15(1)
Show/Hide
|
C33H40FN3O5
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0564507
|
1-[(5-cyano-4-methylpyridin-2-yl)amino]-3-(2,6-dichloropyridin-4-yl)urea
Show/Hide
|
C13H10Cl2N6O
|
3
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 6000 nM
|
|
|
| 3 |
IC50 > 23000 nM
|
|
|
|
CP0549992
|
2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]-2-methylpropanoic acid
Show/Hide
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C24H23ClN4O4
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2
|
| 1 |
IC50 = 7.7 nM
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| 2 |
IC50 = 105 nM
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CP0409055
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2-[4-[3-(4-fluorophenoxy)-5-[[3-hydroxy-3-(2-methylpropyl)pyrrolidine-1-carbonyl]amino]phenoxy]phenyl]-2-methylpropanoic acid
Show/Hide
|
C31H35FN2O6
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1
|
| 1 |
IC50 = 8.2 nM
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CP0377599
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2-[4-[3-[(3-cyclopentyl-3-hydroxypyrrolidine-1-carbonyl)amino]-5-(4-fluorophenoxy)phenoxy]phenyl]-2-methylpropanoic acid
Show/Hide
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C32H35FN2O6
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1
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| 1 |
IC50 = 8.8 nM
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CP0545041
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2-[3-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]phenyl]-2-methylpropanoic acid
Show/Hide
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C32H37FN2O6
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1
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| 1 |
IC50 = 8.8 nM
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CP0575049
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2-[4-[[6-chloro-5-(cyclopropylmethoxy)-1H-benzimidazol-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
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C22H19ClN4O4
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2
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| 1 |
IC50 = 8.8 nM
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| 2 |
IC50 = 25 nM
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CP0528044
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2-[4-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
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C22H19ClN4O4
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2
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| 1 |
IC50 = 9 nM
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| 2 |
IC50 = 86 nM
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CP0407100
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2-[4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]phenyl]propanoic acid
Show/Hide
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C31H35FN2O6
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1
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| 1 |
IC50 = 9.3 nM
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CP0471275
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1-(2,6-dichloropyridin-4-yl)-3-[[4-methyl-5-(1-methylpyrazol-3-yl)pyridin-2-yl]amino]urea
Show/Hide
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C16H15Cl2N7O
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3
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| 1 |
IC50 = 9.3 nM
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| 2 |
IC50 = 4000 nM
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| 3 |
IC50 > 23000 nM
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CP0848005
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[3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
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C19H34NO4P
|
1
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| 1 |
IC50 = 9.8 nM
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CP0575048
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4-[(6-chloro-5-ethoxy-1H-benzimidazol-2-yl)methyl]-2-(2-morpholin-4-yl-2-oxoethyl)phthalazin-1-one
Show/Hide
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C24H24ClN5O4
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2
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| 1 |
IC50 = 10 nM
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| 2 |
IC50 = 22 nM
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CP0568584
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4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]-2-methoxybenzoic acid
Show/Hide
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C30H33FN2O7
|
1
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| 1 |
IC50 = 11 nM
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CP0532872
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2-[4-[[6-chloro-5-(cyclopropylmethoxy)indazol-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
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C22H19ClN4O4
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2
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| 1 |
IC50 = 11 nM
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| 2 |
IC50 = 53 nM
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CP0458951
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4-[3-[[4-(2-ethylbutyl)-4-hydroxypiperidine-1-carbonyl]amino]-5-(4-fluorophenoxy)phenoxy]benzoic acid
Show/Hide
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C31H35FN2O6
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1
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| 1 |
IC50 = 12 nM
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CP0495250
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2-[4-[[6-chloro-5-(2,2-difluoroethoxy)-1H-benzimidazol-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
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C20H15ClF2N4O4
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2
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| 1 |
IC50 = 12 nM
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| 2 |
IC50 = 15 nM
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CP0422752
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1-(6-chloro-2-ethoxy-3-methylpyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H21ClF3N7O2
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3
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| 1 |
IC50 = 15 nM
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| 2 |
IC50 = 4800 nM
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| 3 |
IC50 = 8800 nM
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CP0564519
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1-(2-ethoxy-3,6-dimethylpyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C21H24F3N7O2
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3
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| 1 |
IC50 = 16 nM
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| 2 |
IC50 = 4500 nM
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| 3 |
IC50 = 5200 nM
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CP0555282
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1-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]cyclopropane-1-carboxylic acid
Show/Hide
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C24H21ClN4O4
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2
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| 1 |
IC50 = 16 nM
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| 2 |
IC50 = 82 nM
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CP0377542
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3-fluoro-4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]benzoic acid
Show/Hide
|
C29H30F2N2O6
|
1
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| 1 |
IC50 = 17 nM
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CP0568587
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2-[4-[3-[(3-cyclohexyl-3-hydroxypyrrolidine-1-carbonyl)amino]-5-(4-fluorophenoxy)phenoxy]phenyl]-2-methylpropanoic acid
Show/Hide
|
C33H37FN2O6
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1
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| 1 |
IC50 = 17 nM
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CP0575047
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2-[4-[(6-chloro-5-ethoxy-1H-benzimidazol-2-yl)methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C20H17ClN4O4
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2
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| 1 |
IC50 = 17 nM
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| 2 |
IC50 = 109 nM
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CP0549927
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2-[4-[[5-(cyclopropylmethoxy)-6-fluoro-1H-benzimidazol-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C22H19FN4O4
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2
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| 1 |
IC50 = 18 nM
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| 2 |
IC50 = 180 nM
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CP0545038
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4-[3-(2,4-difluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]benzoic acid
Show/Hide
|
C29H30F2N2O6
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1
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| 1 |
IC50 = 20 nM
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CP0547058
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1-(2-chloro-6-ethoxypyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C19H19ClF3N7O2
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3
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 5000 nM
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| 3 |
IC50 = 7700 nM
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CP0532869
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2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]acetic acid
Show/Hide
|
C22H19ClN4O4
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2
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 30 nM
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CP0379497
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4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-(4-sulfamoylphenoxy)phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C30H36FN3O6S
|
1
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| 1 |
IC50 = 21 nM
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CP0545039
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2-[4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]phenyl]acetic acid
Show/Hide
|
C30H33FN2O6
|
1
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| 1 |
IC50 = 21 nM
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CP0547064
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1-(2-chloro-6-ethoxypyridin-4-yl)-3-[[4-methyl-5-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridin-2-yl]methyl]urea
Show/Hide
|
C20H20ClF3N6O2
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3
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| 1 |
IC50 = 22 nM
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| 2 |
IC50 = 4400 nM
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| 3 |
IC50 = 11000 nM
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CP0532873
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2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]-2-methoxyacetic acid
Show/Hide
|
C23H21ClN4O5
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2
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| 1 |
IC50 = 23 nM
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| 2 |
IC50 = 58 nM
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CP0559220
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1-(6-cyano-2-ethoxy-3-methylpyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C21H21F3N8O2
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3
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| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 5500 nM
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| 3 |
IC50 = 7100 nM
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CP0534009
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(2R)-2-[1-[[7-chloro-6-(cyclopropylmethoxy)imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxocinnolin-3-yl]propanoic acid
Show/Hide
|
C23H21ClN4O4
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2
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| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 253 nM
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CP0413802
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4-[3-(3,4-difluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]benzoic acid
Show/Hide
|
C29H30F2N2O6
|
1
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| 1 |
IC50 = 25 nM
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CP0533837
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1-(3-chloro-2-ethoxy-6-methylpyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H21ClF3N7O2
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3
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| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 4900 nM
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| 3 |
IC50 = 8700 nM
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CP0860724
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[(1S,3S)-3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
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| 1 |
IC50 = 27 nM
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CP0355224
|
4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-[4-(methylcarbamoyl)phenoxy]phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C32H38FN3O5
|
1
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| 1 |
IC50 = 27 nM
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CP0468285
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2-[4-[3-(4-fluorophenoxy)-5-[(3-hydroxy-3-propan-2-ylpyrrolidine-1-carbonyl)amino]phenoxy]phenyl]-2-methylpropanoic acid
Show/Hide
|
C30H33FN2O6
|
1
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| 1 |
IC50 = 29 nM
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CP0546378
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1-[2-ethoxy-6-(trifluoromethyl)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H19F6N7O2
|
3
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 4900 nM
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| 3 |
IC50 = 8800 nM
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CP0575046
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N-[3-chloro-4-(trifluoromethoxy)phenyl]-2-[3-(2-morpholin-4-yl-2-oxoethyl)-4-oxophthalazin-1-yl]acetamide
Show/Hide
|
C23H20ClF3N4O5
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2
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| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 103 nM
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CP0557974
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1-(2,6-dichloropyridin-4-yl)-3-[[6-(hydroxymethyl)-4-methylpyridin-2-yl]amino]urea
Show/Hide
|
C13H13Cl2N5O2
|
3
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| 1 |
IC50 = 31 nM
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| 2 |
IC50 > 23000 nM
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| 3 |
IC50 > 6600 nM
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CP0555284
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2-[4-[[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C19H12ClF3N4O4
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2
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| 1 |
IC50 = 31 nM
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| 2 |
IC50 = 342 nM
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CP0403977
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[(1R,3R)-3-amino-1-hydroxy-5-(4-octylphenyl)pentyl]phosphonic acid
Show/Hide
|
C19H34NO4P
|
2
|
| 1 |
IC50 = 33 nM
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| 2 |
IC50 > 10000 nM
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CP0536470
|
2-fluoro-4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]benzoic acid
Show/Hide
|
C29H30F2N2O6
|
1
|
| 1 |
IC50 = 34 nM
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CP0418623
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1-(2-cyano-6-ethoxypyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H19F3N8O2
|
3
|
| 1 |
IC50 = 35 nM
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| 2 |
IC50 = 5500 nM
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| 3 |
IC50 = 11000 nM
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CP0557976
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1-[2-chloro-6-(2,2-difluoroethoxy)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C19H17ClF5N7O2
|
3
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| 1 |
IC50 = 36 nM
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| 2 |
IC50 = 5100 nM
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| 3 |
IC50 = 7200 nM
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CP0375037
|
N-[3-(4-carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H36FN3O5
|
1
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| 1 |
IC50 = 39 nM
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CP0436276
|
N-[3-(4-fluorophenoxy)-5-(4-sulfamoylphenoxy)phenyl]-4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C30H27F2N3O6S
|
1
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| 1 |
IC50 = 39 nM
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CP0484486
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N-[3-(4-fluorophenoxy)-5-(4-methylsulfonylphenoxy)phenyl]-4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H28F2N2O6S
|
1
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| 1 |
IC50 = 39 nM
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CP0575746
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N-[3-chloro-4-(trifluoromethoxy)phenyl]-2-(4-oxo-3-pyrrolidin-3-ylphthalazin-1-yl)acetamide
Show/Hide
|
C21H18ClF3N4O3
|
2
|
| 1 |
IC50 = 42 nM
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| 2 |
IC50 = 94 nM
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CP0388589
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N-[3-[4-(dimethylcarbamoyl)phenoxy]-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C33H40FN3O5
|
1
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| 1 |
IC50 = 43 nM
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CP0422755
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1-[[5-[(1,3-dimethylpyrazol-4-yl)amino]-4-methylpyridin-2-yl]methyl]-3-[2-ethoxy-6-(trifluoromethyl)pyridin-4-yl]urea
Show/Hide
|
C21H24F3N7O2
|
3
|
| 1 |
IC50 = 55 nM
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| 2 |
IC50 = 4800 nM
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| 3 |
IC50 = 12000 nM
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CP0411436
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4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-(4-methylsulfonylphenoxy)phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H37FN2O6S
|
1
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| 1 |
IC50 = 58 nM
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CP0577931
|
2-[4-[(6-chloro-5-methoxy-1H-benzimidazol-2-yl)methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C19H15ClN4O4
|
2
|
| 1 |
IC50 = 61 nM
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| 2 |
IC50 = 241 nM
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CP0850212
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[(1R,3S)-3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 73 nM
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CP0860694
|
[3-Amino-2-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid; compound with [(E)-3-amino-5-(4-octyl-phenyl)-pent-1-enyl]-phosphonic acid
Show/Hide
|
C38H66N2O7P2
|
1
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| 1 |
IC50 = 76 nM
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CP0509478
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N-[3-(4-carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H27F2N3O5
|
1
|
| 1 |
IC50 = 76 nM
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CP0509477
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N-[3-(4-carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(4-chlorophenyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H27ClFN3O5
|
1
|
| 1 |
IC50 = 83 nM
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CP0398735
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N-[3-(4-cyanophenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H34FN3O4
|
1
|
| 1 |
IC50 = 84 nM
|
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CP0398734
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N-[3-(2-carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H36FN3O5
|
1
|
| 1 |
IC50 = 88 nM
|
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CP0387271
|
4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-4-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C29H34FN3O4
|
1
|
| 1 |
IC50 = 93 nM
|
|
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CP0393661
|
[3-amino-5-(4-octylphenyl)pentyl]phosphonic acid
Show/Hide
|
C19H34NO3P
|
2
|
| 1 |
IC50 = 100 nM
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|
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| 2 |
IC50 > 10000 nM
|
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CP0471276
|
1-(2-chloro-6-ethoxypyridin-4-yl)-3-[[5-(2,6-dimethylmorpholin-4-yl)-4-methylpyridin-2-yl]methyl]urea
Show/Hide
|
C21H28ClN5O3
|
3
|
| 1 |
IC50 = 105 nM
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|
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| 2 |
IC50 = 4200 nM
|
|
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| 3 |
IC50 = 16000 nM
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CP0534010
|
2-[4-[(6-chloro-5-ethoxyindazol-2-yl)methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C20H17ClN4O4
|
2
|
| 1 |
IC50 = 113 nM
|
|
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| 2 |
IC50 = 149 nM
|
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|
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CP0577932
|
2-[4-[(5-chloro-6-ethoxyindazol-2-yl)methyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C20H17ClN4O4
|
2
|
| 1 |
IC50 = 113 nM
|
|
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| 2 |
IC50 > 6640 nM
|
|
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CP0407758
|
N-[3-(4-fluorophenoxy)-5-pyridin-4-yloxyphenyl]-4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C29H25F2N3O4
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
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CP0453571
|
(3-Tridecylamino-propyl)-phosphonic acid
Show/Hide
|
C16H36NO3P
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
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CP0387270
|
N-[3-(3-carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C31H36FN3O5
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
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CP0471266
|
1-[2-(2-hydroxyethoxy)-3-methyl-6-(trifluoromethyl)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C21H21F6N7O3
|
3
|
| 1 |
IC50 = 169 nM
|
|
|
| 2 |
IC50 = 4400 nM
|
|
|
| 3 |
IC50 = 84000 nM
|
|
|
|
CP0555283
|
2-[4-[2-(5-chloro-2,4-dimethoxyanilino)-2-oxoethyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C20H18ClN3O6
|
3
|
| 1 |
IC50 = 186 nM
|
|
|
| 2 |
IC50 = 464 nM
|
|
|
| 3 |
IC50 > 23300 nM
|
|
|
|
CP0488664
|
N-[3-chloro-4-(trifluoromethoxy)phenyl]-2-(3-ethyl-4-oxophthalazin-1-yl)acetamide
Show/Hide
|
C19H15ClF3N3O3
|
2
|
| 1 |
IC50 = 199 nM
|
|
|
| 2 |
IC50 = 473 nM
|
|
|
|
CP0477277
|
4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-3-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C29H34FN3O4
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0555285
|
N-[3-chloro-4-(trifluoromethoxy)phenyl]-2-(3-cyclopropyl-4-oxophthalazin-1-yl)acetamide
Show/Hide
|
C20H15ClF3N3O3
|
2
|
| 1 |
IC50 = 218 nM
|
|
|
| 2 |
IC50 = 565 nM
|
|
|
|
CP0478347
|
[3-amino-3-(hydroxymethyl)-5-(4-octylphenyl)pentyl]phosphonic acid
Show/Hide
|
C20H36NO4P
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0868637
|
[3-Amino-2-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0533834
|
1-(2-ethoxy-6-methylpyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H22F3N7O2
|
3
|
| 1 |
IC50 = 242 nM
|
|
|
| 2 |
IC50 = 4400 nM
|
|
|
| 3 |
IC50 = 54000 nM
|
|
|
|
CP0411434
|
4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-2-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C29H34FN3O4
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0376811
|
3-[(4-nonylphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
2
|
| 1 |
IC50 = 320 nM
|
|
|
| 2 |
IC50 = 750 nM
|
|
|
|
CP0379285
|
2-[(2R,5S)-5-tetradecylpyrrolidin-2-yl]ethylphosphonic acid
Show/Hide
|
C20H42NO3P
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0532868
|
2-[4-[2-[3-chloro-4-(trifluoromethoxy)anilino]-2-oxoethyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C19H13ClF3N3O5
|
3
|
| 1 |
IC50 = 389 nM
|
|
|
| 2 |
IC50 = 754 nM
|
|
|
| 3 |
IC50 > 23300 nM
|
|
|
|
CP0388588
|
4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-methylphenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C25H33FN2O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0402395
|
3-(10-phenyldecylamino)propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0406502
|
(3-Tetradecylamino-propyl)-phosphonic acid
Show/Hide
|
C17H38NO3P
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0533835
|
1-[2-chloro-6-(2-methoxyethoxy)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H21ClF3N7O3
|
2
|
| 1 |
IC50 = 640 nM
|
|
|
| 2 |
IC50 = 3500 nM
|
|
|
|
CP0546377
|
1-[2-(2-hydroxyethoxy)-6-(trifluoromethyl)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C20H19F6N7O3
|
2
|
| 1 |
IC50 = 704 nM
|
|
|
| 2 |
IC50 = 4000 nM
|
|
|
|
CP0373686
|
(3-Hexadecylamino-propyl)-phosphonic acid
Show/Hide
|
C19H42NO3P
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0380620
|
(3-Pentadecylamino-propyl)-phosphonic acid
Show/Hide
|
C18H40NO3P
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0379498
|
4-(2-ethylbutyl)-4-hydroxy-N-(3-methyl-5-phenoxyphenyl)piperidine-1-carboxamide
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0506943
|
3-[(4-nonoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0387268
|
N-[3-chloro-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C24H30ClFN2O3
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0398647
|
N-[3,5-bis(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C30H34F2N2O4
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0454272
|
4-Amino-6-(4-octyl-phenyl)-hexanoic acid
Show/Hide
|
C20H33NO2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0881026
|
3-(N-alkylamino) propylphosphonic acid derivative
Show/Hide
|
C19H36NO5P
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0398427
|
[2-amino-1-hydroxy-4-(4-octylphenyl)butan-2-yl] dihydrogen phosphate
Show/Hide
|
C18H32NO5P
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0407756
|
4-(2-ethylbutyl)-1-[4-fluoro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]piperidin-4-ol
Show/Hide
|
C19H25F4N3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0550000
|
2-[4-[2-(5-chloro-2-methoxyanilino)-2-oxoethyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C19H16ClN3O5
|
3
|
| 1 |
IC50 = 1190 nM
|
|
|
| 2 |
IC50 > 23300 nM
|
|
|
| 3 |
IC50 > 1790 nM
|
|
|
|
CP0374689
|
(3-Amino-heptadecyl)-phosphonic acid
Show/Hide
|
C17H38NO3P
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0411435
|
4-(2-ethylbutyl)-4-hydroxy-N-[3-(2-methylphenoxy)phenyl]piperidine-1-carboxamide
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0413780
|
4-(2-ethylbutyl)-4-hydroxy-N-[3-(4-methylphenoxy)phenyl]piperidine-1-carboxamide
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0494561
|
US8975409, Comparative compound B
Show/Hide
|
C24H31FN2O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0535410
|
4-(2-ethylbutyl)-4-hydroxy-N-[3-(3-methylphenoxy)phenyl]piperidine-1-carboxamide
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0398502
|
N-[3-ethoxy-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C26H35FN2O4
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0498260
|
3-[[4-(5-heptyl-1,2,4-oxadiazol-3-yl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C19H30N3O4P
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0481799
|
4-(2-ethylbutyl)-4-hydroxy-N-(4-methyl-3-phenoxyphenyl)piperidine-1-carboxamide
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0396413
|
4-(2-ethylbutyl)-N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C19H26F4N2O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0484517
|
US8975409, Comparative compound A
Show/Hide
|
C25H30F4N2O3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0384389
|
3-[4-(4-heptylphenyl)butylamino]propylphosphonic acid
Show/Hide
|
C20H36NO3P
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0414924
|
(3-Amino-13-phenyl-tridecyl)-phosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0445772
|
3-[methyl(tetradecyl)amino]propylphosphonic acid
Show/Hide
|
C18H40NO3P
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0373301
|
3-[3-(4-heptylphenyl)propylamino]propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0571500
|
4-(2-ethylbutyl)-4-hydroxy-N-(3-phenoxyphenyl)piperidine-1-carboxamide
Show/Hide
|
C24H32N2O3
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0448991
|
3-[[4-(2-heptyltetrazol-5-yl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C18H30N5O3P
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0450587
|
4-(4-bromophenyl)-N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C19H17BrF4N2O2
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0551198
|
1-[2-[2-(dimethylamino)ethoxy]-6-(trifluoromethyl)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C22H24F6N8O2
|
2
|
| 1 |
IC50 = 3000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0487372
|
3-Amino-5-(4-octyl-phenyl)-pentanoic acid
Show/Hide
|
C19H31NO2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0488667
|
2-[1-[2-(5-chloro-2,4-dimethoxyanilino)-2-oxoethyl]indazol-3-yl]acetic acid
Show/Hide
|
C19H18ClN3O5
|
3
|
| 1 |
IC50 = 3360 nM
|
|
|
| 2 |
IC50 = 8980 nM
|
|
|
| 3 |
IC50 > 23300 nM
|
|
|
|
CP0404436
|
3-[[4-(4-hexylphenyl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C22H32NO3P
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0396414
|
4-(4-chlorophenyl)-N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C19H17ClF4N2O2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0454291
|
3-Amino-5-(4-octyl-phenyl)-pentane-1-sulfonic acid
Show/Hide
|
C19H33NO3S
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0567703
|
N-cyclopropyl-6-[2-[(2,6-dichloropyridin-4-yl)carbamoyl]hydrazinyl]-4-methylpyridine-2-carboxamide
Show/Hide
|
C16H16Cl2N6O2
|
2
|
| 1 |
IC50 = 4500 nM
|
|
|
| 2 |
IC50 > 23000 nM
|
|
|
|
CP0457473
|
3-[(4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H32NO4P
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0409210
|
3-[(3-fluoro-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H31FNO4P
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0430984
|
3-[[4-(1-hydroxynonyl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0421389
|
3-[(3-bromo-4-hexoxy-5-methoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C17H29BrNO5P
|
1
|
| 1 |
IC50 = 6500 nM
|
|
|
|
CP0382451
|
3-[(4-nonanoylphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H32NO4P
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0453279
|
4-(4-fluorophenyl)-N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C19H17F5N2O2
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
|
CP0409183
|
3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)butanoic acid
Show/Hide
|
C23H23F3N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0434248
|
3-(5-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-3-yl}-6-methylpyridin-2-yl)propanoic acid
Show/Hide
|
C21H20N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0463957
|
2-methyl-3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)propanoic acid
Show/Hide
|
C23H23F3N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0847942
|
(1R,2R)-2-(4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)cyclopropanecarboxylic acid
Show/Hide
|
C23H21N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0876631
|
(1R,2S)-2-(4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)cyclopropanecarboxylic acid
Show/Hide
|
C23H21N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0906035
|
(1R,2R)-2-(4-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)cyclopropanecarboxylic acid
Show/Hide
|
C23H21F3N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0374881
|
1,2,4-oxadiazole based compound, 26
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384362
|
1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H20F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384392
|
2-(trans-5-(4-(5-(4-(4,4-difluorocyclohexyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384393
|
2-(trans-5-(4-(5-(4-((R)-3,3-difluorocyclopentyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C25H25F2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384395
|
2-(trans-5-(4-(5-(4-(3,3,3-trifluoropropyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384397
|
2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384399
|
2-(trans-5-(4-(5-(4-cyclopentylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384400
|
2-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384401
|
2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C24H22F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0390461
|
2-(cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0446328
|
5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)phenyl)pyrrolidine-3-carboxylic acid
Show/Hide
|
C23H20F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0378040
|
1,2,4-oxadiazole based compound, 22
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0391844
|
1,2,4-oxadiazole based compound, 36
Show/Hide
|
C24H23F2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0391846
|
1,2,4-oxadiazole based compound, 37
Show/Hide
|
C24H23F2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0393959
|
1,3,4-oxadiazole based compound, 9
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0393962
|
1,2,4-oxadiazole based compound, 21
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0393963
|
1,2,4-oxadiazole based compound, 24
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0393967
|
1,2,4-oxadiazole based compound, 29
Show/Hide
|
C22H23N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0393969
|
1,2,4-oxadiazole based compound, 30
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0431020
|
1,2,4-oxadiazole based compound, 25
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0431023
|
1,2,4-oxadiazole based compound, 27
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C24H27N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0431223
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1,2,4-oxadiazole based compound, 34
Show/Hide
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C25H21N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0431224
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1,2,4-oxadiazole based compound, 35
Show/Hide
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C22H20F3N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0436128
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1,2,4-oxadiazole based compound, 32
Show/Hide
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C24H25N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0436191
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1,2,4-oxadiazole based compound, 23
Show/Hide
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C22H23N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0446402
|
1,2,4-oxadiazole based compound, 31
Show/Hide
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C23H23N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0456422
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1,2,4-oxadiazole based compound, 13
Show/Hide
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C23H25N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0485046
|
1,2,4-oxadiazole based compound, 28
Show/Hide
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C21H21N3O4
|
1
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| 1 |
IC50 > 10000 nM
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CP0485409
|
1,2,4-oxadiazole based compound, 33
Show/Hide
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C25H27N3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0373279
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(3-Amino-octadecyl)-phosphonic acid
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C18H40NO3P
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0379112
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(3-Dodecylamino-propyl)-phosphonic acid
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C15H34NO3P
|
1
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| 1 |
IC50 > 10000 nM
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CP0384390
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2-Hydroxy-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
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C20H33NO3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0393677
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(3-Amino-pentadecyl)-phosphonic acid
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C15H34NO3P
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0402450
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3-[2-(4-octylphenyl)ethylamino]propylphosphonic acid
Show/Hide
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C19H34NO3P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0403608
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4-(4-Nonyl-benzylamino)-butyric acid
Show/Hide
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C20H33NO2
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0403972
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(3-Amino-henicosyl)-phosphonic acid
Show/Hide
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C21H46NO3P
|
1
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| 1 |
IC50 > 10000 nM
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CP0404002
|
2,2-Difluoro-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
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C20H31F2NO2
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0413075
|
3-Hydroxy-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
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C20H33NO3
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0418882
|
(3-Amino-hexadecyl)-phosphonic acid
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C16H36NO3P
|
1
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| 1 |
IC50 > 10000 nM
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CP0419093
|
methyl-[3-[(4-nonylphenyl)methylamino]propyl]phosphinic acid
Show/Hide
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C20H36NO2P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0854351
|
hydrogen (3-{[(4-nonylphenyl)methyl]amino}propyl)phosphonite
Show/Hide
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C19H34NO2P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0377169
|
3-[(3-methyl-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C19H34NO4P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0391327
|
3-[(3-chloro-5-methoxy-4-octoxyphenyl)methylamino]propylphosphonic acid
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C19H33ClNO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0404437
|
3-[(3-bromo-4-octoxyphenyl)methylamino]propylphosphonic acid
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C18H31BrNO4P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0404466
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3-[(3-bromo-5-methoxy-4-undecoxyphenyl)methylamino]propylphosphonic acid
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C22H39BrNO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0409209
|
4-[(3-Phosphono-propylamino)-methyl]-benzoic acid heptyl ester
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C18H30NO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0410003
|
3-[(3-methoxy-5-methyl-4-octoxyphenyl)methylamino]propylphosphonic acid
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C20H36NO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0428536
|
3-(3-bromo-5-methoxy-4-(octyloxy)benzylamino)propylphosphonic acid
Show/Hide
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C19H33BrNO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0431648
|
3-[(4-octylphenyl)methylamino]propylphosphonic acid
Show/Hide
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C18H32NO3P
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0434360
|
3-[(3,5-dibromo-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C18H30Br2NO4P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0437625
|
3-[(3-hydroxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C18H32NO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0453216
|
3-[(3-chloro-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C18H31ClNO4P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0453348
|
3-[(3-bromo-4-heptoxy-5-methoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C18H31BrNO5P
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0453944
|
3-[(3,5-dichloro-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C18H30Cl2NO4P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0453952
|
3-[(3,5-dimethyl-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C20H36NO4P
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0453956
|
3-[(3-methoxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C19H34NO5P
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0463921
|
3-[(3-ethoxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C20H36NO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0492236
|
3-[(3-bromo-4-decoxy-5-methoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C21H37BrNO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0389839
|
3-[(3-bromo-5-methoxy-4-nonoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
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C20H35BrNO5P
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0378758
|
(+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0378759
|
(+/-)-2-(cis-5-(4-(5-(4-((R)-3,3-difluorocyclopentyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H25F2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0378760
|
(+/-)-2-(cis-5-(4-(5-(4-((S)-3,3-difluorocyclopentyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H25F2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0378761
|
(+/-)-2-(cis-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0378772
|
(+/-)-3-(cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)propanoic acid
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0378773
|
(+/-)-2-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0378774
|
(+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)propanoic acid
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0378775
|
(+/-)-2-(cis-5-(4-(5-(4-cyclopentyl-3-fluorophenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H26FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0424726
|
(+/-)-2-(cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0436082
|
(+/-)-2-(cis-5-(4-(5-(4-cyclopentyl-2-fluorophenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H26FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0441771
|
(+/-)-trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0084726
|
2-(4-octylphenethyl)-2-aminopropane-1,3-diol
Show/Hide
|
C19H33NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0306592
|
5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole
Show/Hide
|
C20H10F6N2OS
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0403262
|
1-(4-nonylbenzyl)pyrrolidin-3-ylphosphonic acid
Show/Hide
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C20H34NO3P
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 1000 nM
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|
|
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CP0405741
|
1-(4-nonylbenzyl)pyrrolidine-3-carboxylic acid
Show/Hide
|
C21H33NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0405742
|
3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole
Show/Hide
|
C19H9Cl2F3N2OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0405750
|
1-(3-ethyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H24F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419845
|
3-phenyl-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole
Show/Hide
|
C19H11F3N2OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419846
|
1-(4-nonylbenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C20H31NO2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419847
|
1-(3,5-dichloro-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H18Cl2F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419848
|
1-(3-fluoro-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H19F4NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419849
|
1-(3-bromo-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H19BrF3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419850
|
1-(3-methoxy-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H22F3NO4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419851
|
1-(3-methyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H22F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419852
|
1-(4-(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H18F3N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0419853
|
1-(3-chloro-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H19ClF3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0425423
|
1-(3,5-dimethyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H24F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0428538
|
1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)pyrrolidine-3-carboxylic acid
Show/Hide
|
C24H22F3NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0443173
|
26-tert-butyl-13-(2,4,4-trimethylpentan-2-yl)-3,6,9,16,19,22-hexaoxatricyclo[22.3.1.0^{10,15}]octacosa-1(28),10(15),11,13,24,26-hexaene-28-carboxylic acid
Show/Hide
|
C24H19F6NO3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0872791
|
sodium 4-[(4-butoxyphenyl)thio]-20-[1-hydroxy-4-[(5-hydroxyheptyl)oxy]but-2-yn-1-yl]biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO7S2
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
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CP0533836
|
1-[2-(2,3-dihydroxypropoxy)-6-(trifluoromethyl)pyridin-4-yl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C21H21F6N7O4
|
2
|
| 1 |
IC50 > 11000 nM
|
|
|
| 2 |
IC50 < 3000 nM
|
|
|
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CP0549925
|
2-[3-[2-(5-chloro-2,4-dimethoxyanilino)-2-oxoethyl]indol-1-yl]acetic acid
Show/Hide
|
C20H19ClN2O5
|
3
|
| 1 |
IC50 = 17670 nM
|
|
|
| 2 |
IC50 > 23300 nM
|
|
|
| 3 |
IC50 > 6640 nM
|
|
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CP0422754
|
2,6-dichloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]pyridine-4-carboxamide
Show/Hide
|
C18H17Cl2N5O
|
3
|
| 1 |
IC50 > 19000 nM
|
|
|
| 2 |
IC50 > 100 nM
|
|
|
| 3 |
IC50 < 1700 nM
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|
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CP0570239
|
6-[2-[(2,6-dichloropyridin-4-yl)carbamoyl]hydrazinyl]-N,N,4-trimethylpyridine-2-carboxamide
Show/Hide
|
C15H16Cl2N6O2
|
2
|
| 1 |
IC50 > 19000 nM
|
|
|
| 2 |
IC50 > 23000 nM
|
|
|
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CP0570372
|
2-(3,4-dichlorophenyl)-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]acetamide
Show/Hide
|
C20H20Cl2N4O
|
2
|
| 1 |
IC50 > 19000 nM
|
|
|
| 2 |
IC50 < 1000 nM
|
|
|
|
CP0549999
|
N-(5-chloro-2,4-dimethoxyphenyl)-2-(1-methylindol-3-yl)acetamide
Show/Hide
|
C19H19ClN2O3
|
3
|
| 1 |
IC50 = 19240 nM
|
|
|
| 2 |
IC50 > 23300 nM
|
|
|
| 3 |
IC50 > 8130 nM
|
|
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CP0495249
|
2-[4-[2-(2,4-dimethoxyanilino)-2-oxoethyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C20H19N3O6
|
2
|
| 1 |
IC50 > 19900 nM
|
|
|
| 2 |
IC50 > 23300 nM
|
|
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CP0546381
|
1-(3-cyano-2-ethoxy-6-methylpyridin-4-yl)-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea
Show/Hide
|
C21H21F3N8O2
|
2
|
| 1 |
IC50 > 20000 nM
|
|
|
| 2 |
IC50 < 2300 nM
|
|
|
|
CP0544157
|
N-cyclopropyl-6-[2-[(2,6-dichloropyridin-4-yl)carbamoyl]hydrazinyl]-N,4-dimethylpyridine-2-carboxamide
Show/Hide
|
C17H18Cl2N6O2
|
2
|
| 1 |
IC50 > 20000 nM
|
|
|
| 2 |
IC50 > 23000 nM
|
|
|
|
CP0511475
|
4-(2-ethylbutyl)-4-hydroxy-N-(2-methyl-3-phenoxyphenyl)piperidine-1-carboxamide
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0372160
|
[(2R)-2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate
Show/Hide
|
C19H34NO5P
|
1
|
| 1 |
IC50 > 22000 nM
|
|
|
|
CP0375771
|
(S)-2-amino-4-(4-(heptyloxy)phenyl)-2-methylbutanoic acid
Show/Hide
|
C18H29NO3
|
1
|
| 1 |
IC50 > 22000 nM
|
|
|
|
CP0375772
|
(S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentanoic acid
Show/Hide
|
C19H31NO3
|
1
|
| 1 |
IC50 > 22000 nM
|
|
|
|
CP0381221
|
(S)-4-amino-6-(4-(heptyloxy)phenyl)-4-methylhexanoic acid
Show/Hide
|
C20H33NO3
|
1
|
| 1 |
IC50 > 22000 nM
|
|
|
|
CP0390201
|
(S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 > 22000 nM
|
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CP0390202
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(S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentane-1-sulfonic acid
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C19H33NO4S
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1
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| 1 |
IC50 > 22000 nM
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CP0390203
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(S)-1-(4-(heptyloxy)phenyl)-3-methyl-5-(1H-tetrazol-5-yl)pentan-3-amine
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C20H33N5O
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1
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| 1 |
IC50 > 22000 nM
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CP0430641
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(S)-2-amino-4-(4-(heptyloxy)phenyl)-2-methylbutyl dihydrogen phosphate
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C18H32NO5P
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1
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| 1 |
IC50 > 22000 nM
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CP0447433
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5-[(S)-3-Amino-5-(4-heptyloxy-phenyl)-3-methyl-pentyl]-1,1-dioxo-1lambda*6*-[1,2,5]thiadiazolidin-3-one
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C21H35N3O4S
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1
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| 1 |
IC50 > 22000 nM
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CP0562798
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1-[(6-cyano-4-methylpyridin-2-yl)amino]-3-(2,6-dichloropyridin-4-yl)urea
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C13H10Cl2N6O
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2
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| 1 |
IC50 > 23000 nM
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| 2 |
IC50 > 6600 nM
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CP0882743
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sodium 4-[(4-butoxyphenyl)thio]-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
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C35H43NaO5S2
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1
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| 1 |
IC50 = 24000 nM
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CP0542511
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4-(2-ethylbutyl)-4-hydroxy-N-(2-methyl-5-phenoxyphenyl)piperidine-1-carboxamide
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C25H34N2O3
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1
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| 1 |
IC50 > 25000 nM
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CP0407757
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4-(4-bromophenyl)-N-[3-fluoro-5-(trifluoromethyl)phenyl]piperidine-1-carboxamide
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C19H17BrF4N2O
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1
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| 1 |
IC50 > 25000 nM
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CP0538176
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4-(4-bromophenyl)-4-fluoro-N-[3-fluoro-5-(trifluoromethyl)phenyl]piperidine-1-carboxamide
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C19H16BrF5N2O
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1
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| 1 |
IC50 > 25000 nM
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CP0379286
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(2-Tetradecylamino-cyclohexylmethyl)-phosphonic acid
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C21H44NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0379287
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(3-Tetradecylamino-cyclopentyl)-phosphonic acid
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C19H40NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0379288
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(3-Tetradecylamino-cyclohexyl)-phosphonic acid
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C20H42NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0392505
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[(1S,3S)-3-[(4-nonylphenyl)methylamino]cyclohexyl]phosphonic acid
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C22H38NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0393495
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2-(1-tetradecylpyrrolidin-2-yl)ethylphosphonic acid
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C20H42NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0393499
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(3-Hydroxy-1-tetradecyl-pyrrolidin-3-yl)-phosphonic acid
Show/Hide
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C18H38NO4P
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1
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| 1 |
IC50 > 1000 nM
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CP0430889
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3-(2-tetradecylpyrrolidin-1-yl)propylphosphonic acid
Show/Hide
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C21H44NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0433608
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(4-Hydroxy-2-tetradecyl-piperidin-4-yl)-methyl-phosphinic acid
Show/Hide
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C20H42NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0464605
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(4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-phosphinic acid
Show/Hide
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C20H42NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0485396
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3-(2-tridecylpiperidin-1-yl)propylphosphonic acid
Show/Hide
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C21H44NO3P
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1
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| 1 |
IC50 > 1000 nM
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CP0916381
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[Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-phosphonic acid
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C19H40NO4P
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1
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| 1 |
IC50 > 1000 nM
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CP0447807
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3-Fluoro-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
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C20H32FNO2
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1
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| 1 |
IC50 > 1000 nM
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