Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-chloro-N-[[5-(1,3-dimethylpyrazol-4-yl)-4-methylpyridin-2-yl]methyl]-4-ethoxy-1H-imidazo[4,5-c]pyridin-2-amine
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Canonical SMILES
CCOc1nc(Cl)cc2nc(NCc3cc(C)c(cn3)-c3cn(C)nc3C)[nH]c12
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Compound Formula C20H22ClN7O
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
O95136
Gene Name
S1PR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 2.25 nM
   TI
   LI
   LO
   TS
2
IC50 = 33 nM
   TI
   LI
   LO
   TS
3
IC50 = 4200 nM
   TI
   LI
   LO
   TS
CL000673 HFL1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.25 nM
   TI
   LI
   LO
   TS