Brief Information of the Compound and Protein
Compound Name
1-[(5-cyano-4-methylpyridin-2-yl)amino]-3-(2,6-dichloropyridin-4-yl)urea
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Canonical SMILES
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1C#N
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Compound Formula C13H10Cl2N6O
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
O95136
Gene Name
S1PR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
IC50 = 6000 nM
   TI
   LI
   LO
   TS
3
IC50 > 23000 nM
   TI
   LI
   LO
   TS