Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01549 , Mu-type opioid receptor
Gene Name OPRM1
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P33535
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01549
 
Compound ID Compound Name Compound Formula
CP0087118
(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-6-[[3-oxo-3-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)propyl]carbamoylamino]hexanoic acid
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C86H122ClN21O15
 1
1
EC50 = 0.2 nM
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CP0100639
(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-[2-oxo-2-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)ethyl]pentanamide
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C50H64N8O7
 1
1
EC50 = 0.59 nM
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CP0342087
(3R)-4-[[(2R)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2R)-2-[[(2S)-3-(1H-indol-2-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]hexanoyl]amino]-4-oxobutanoic acid
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C58H73N11O13
 2
1
EC50 = 1.3 nM
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2
IC50 = 1.259 nM
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CP0336175
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-6-[[3-oxo-3-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)propyl]carbamoylamino]hexanamide
   Show/Hide
C101H143N27O15
 1
1
EC50 = 1.4 nM
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CP0369953
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-6-[[3-oxo-3-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)propyl]carbamoylamino]hexanoic acid
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C75H100N16O12
 1
1
EC50 = 1.5 nM
   TI
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CP0342086
(3R)-4-[[(2R)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2R)-2-[[(2S)-2-amino-3-(1H-indol-2-yl)propanoyl]amino]hexanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C53H65N11O11
 2
1
EC50 = 1.9 nM
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2
IC50 = 1.862 nM
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CP0042126
(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-(2,3,4,5,6-pentafluorophenyl)propan-2-yl]-N'-[6-oxo-6-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)hexyl]pentanediamide
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C62H72ClF5N10O9
 1
1
EC50 = 2.2 nM
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CP0528414
3-[(dimethylamino)methyl]-4-hydroxy-4-(3-hydroxyphenyl)-N-phenylpiperidine-1-carboxamide;hydrochloride
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C21H28ClN3O3
 2
1
EC50 = 2.3 nM
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2
Ki = 1.2 nM
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CP0261470
(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-6-[[3-oxo-3-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)propyl]carbamoylamino]hexanoic acid
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C64H90N14O11
 1
1
EC50 = 2.8 nM
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CP0045380
(2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide
   Show/Hide
C46H56N10O10
 2
1
EC50 = 6 nM
   TI
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2
EC50 = 12 nM
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CP0176551
(3S)-2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-N-[(2R)-3-(4-chlorophenyl)-1-oxo-1-[4-(N-propanoylanilino)piperidin-1-yl]propan-2-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
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C44H50ClN5O5
 1
1
EC50 = 6.2 nM
   TI
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CP0288627
(3R)-4-[[(2R)-1-[[(2S)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-3-(1H-indol-2-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C53H65N11O11
 2
1
EC50 = 7.7 nM
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2
IC50 = 7.762 nM
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CP0043301
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide
   Show/Hide
C26H35N5O6
 4
1
EC50 = 8.06 nM
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2
EC50 = 81 nM
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3
IC50 = 3 nM
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4
Ki = 2.3 nM
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CP0266403
(2S)-2-amino-3-(4-hydroxyphenyl)-N-[(2R)-1-oxo-1-[[2-oxo-2-[[(2S)-1-oxo-1-[[2-oxo-2-[[2-oxo-2-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)ethyl]amino]ethyl]amino]-3-phenylpropan-2-yl]amino]ethyl]amino]propan-2-yl]propanamide
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C46H56N8O7
 1
1
EC50 = 9.1 nM
   TI
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   TS
CP0380169
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-(2,3,4,5,6-pentafluorophenyl)propan-2-yl]-N'-[6-oxo-6-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)hexyl]pentanediamide
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C74H96F5N15O11
 1
1
EC50 = 12 nM
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CP0324103
(3R)-4-[[(2R)-1-[[(2S)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-3-(1H-indol-2-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-[[(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-4-oxobutanoic acid
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C58H73N11O13
 2
1
EC50 = 17 nM
   TI
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2
IC50 = 173.78 nM
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CP0266417
(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-[2-oxo-2-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)ethyl]pentanamide
   Show/Hide
C51H66N8O7
 1
1
EC50 = 35 nM
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CP0369954
(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methyl-N-[2-oxo-2-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)ethyl]pentanamide
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C49H62N8O7
 1
1
EC50 = 45 nM
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CP0369952
(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-2-methylpropanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-N'-[2-oxo-2-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)ethyl]pentanediamide
   Show/Hide
C61H83N11O10
 1
1
EC50 = 56 nM
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CP0680488
(S)-2-amino-3-(4-hydroxyphenyl)-N-((R)-1-oxo-1-(2-oxo-2-((S)-1-oxo-1-(3-oxo-3-((1-phenethylpiperidin-4-yl)(phenyl)amino)propylamino)-3-phenylpropan-2-ylamino)ethylamino)propan-2-yl)propanamide hydrochloride
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C45H56ClN7O6
 1
1
EC50 = 60 nM
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CP0100342
(S)-2-amino-3-(4-hydroxy-phenyl)-N-((R)-1-{[((S)-1-{2-[(1-phenethyl-piperidin-4-yl)-phenyl-carbamoyl]-ethylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-propionamide
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C45H55N7O6
 1
1
EC50 = 69 nM
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CP0288626
(3S)-4-[[(2S)-1-[[(2R)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-3-(1H-indol-2-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C53H65N11O11
 2
1
EC50 = 75 nM
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2
IC50 = 74.13 nM
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CP0328410
(2S)-2-amino-N-[(4S,10S,15S,21S)-21-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-10,15-dibenzyl-3,3,22,22-tetramethyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexazacyclodocos-4-yl]-3-(4-hydroxyphenyl)propanamide
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C50H62N10O10S2
 1
1
EC50 = 76.2 nM
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CP0390907
[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]methanol
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C26H35NO4
 1
1
EC50 = 87.3 nM
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CP0324104
(3S)-3-[(2S)-2-[(2R)-2-amino-3-(1H-indol-2-yl)propanamido]hexanamido]-3-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanehydrazido]-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid
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C53H65N11O11
 2
1
EC50 = 96 nM
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2
IC50 = 9.55 nM
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CP0000305
(-)-(etorphine)
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C17H19NO3
 2
1
EC50 = 123.5 nM
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2
Ki = 116.8 nM
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CP0396635
[(1R,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,18-tetraen-16-yl]-phenylmethanone
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C31H33NO4
 1
1
EC50 = 130.2 nM
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CP0390005
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-(4-methoxyphenyl)methanone
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C33H39NO5
 1
1
EC50 = 146 nM
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CP0389202
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-[4-(trifluoromethyl)phenyl]methanone
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C33H36F3NO4
 1
1
EC50 = 164.6 nM
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CP0211343
(3S)-3-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanehydrazido]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-3-[(2S)-2-[(2R)-2-{[(tert-butoxy)carbonyl]amino}-3-(1H-indol-2-yl)propanamido]hexanamido]propanoic acid
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C58H73N11O13
 2
1
EC50 = 210 nM
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2
IC50 = 204.17 nM
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CP0087116
(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N'-[2-oxo-2-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)ethyl]pentanediamide
   Show/Hide
C59H79N11O10
 1
1
EC50 = 220 nM
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CP0325247
(2S)-2-amino-N-[(4R,10S,15S,21R)-21-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-10,15-dibenzyl-3,3,22,22-tetramethyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexazacyclodocos-4-yl]-3-(4-hydroxyphenyl)propanamide
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C50H62N10O10S2
 1
1
EC50 = 230 nM
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CP0159328
3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol
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C15H23NO2
 2
1
EC50 = 244.7 nM
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2
Ki = 13 nM
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CP0087117
(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-4-methylpentanoyl]amino]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-N'-[3-oxo-3-(N-[1-(2-phenylethyl)piperidin-4-yl]anilino)propyl]pentanediamide
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C64H88ClN11O10
 1
1
EC50 = 380 nM
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CP0396636
(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene-16-carbaldehyde
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C26H33NO4
 1
1
EC50 = 427.7 nM
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CP0324102
(3S)-4-[[(2S)-1-[[(2R)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-3-(1H-indol-2-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C58H73N11O13
 2
1
EC50 = 630 nM
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2
IC50 = 630.96 nM
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CP0390006
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-(4-phenylphenyl)methanone
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C38H41NO4
 1
1
EC50 = 766 nM
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CP0402128
N-benzyl-4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]aniline
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C37H42N2O3
 2
1
EC50 = 1426 nM
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2
Ki = 319.2 nM
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CP0389201
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-phenylmethanone
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C32H37NO4
 1
1
EC50 = 1597 nM
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CP0384887
(2R)-2-[[(2R)-2-[[2-[[(1R,2S)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclohexanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
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C33H45N5O8
 1
1
IC50 = 0.25 nM
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CP0076658
(R)-2-[(R)-2-(2-{2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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C28H37N5O7
 1
1
IC50 = 1.8 nM
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CP0375306
(2R)-2-[[(2R)-2-[[2-[[(1R,2S)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclopentanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C32H43N5O8
 1
1
IC50 = 2.5 nM
   TI
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   TS
CP0402489
(R)-2-[(R)-2-(2-{(R)-2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-2-methyl-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
   Show/Hide
C30H41N5O8
 1
1
IC50 = 6.3 nM
   TI
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   TS
CP0455130
(2R)-2-[[(2R)-2-[[2-[[(1R,2R)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclohexanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C33H45N5O8
 1
1
IC50 = 50 nM
   TI
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   TS
CP0375261
(R)-2-[(R)-2-(2-{2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
   Show/Hide
C30H41N5O7
 1
1
IC50 = 158 nM
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   TS
CP0399819
(2R)-2-[[(2R)-2-[[2-[[(1S,2R)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclopentanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
   Show/Hide
C32H43N5O8
 1
1
IC50 = 320 nM
   TI
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   TS
CP0437453
(R)-2-[(R)-2-(2-{(S)-2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-2-methyl-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
   Show/Hide
C30H41N5O8
 1
1
IC50 > 10000 nM
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CP0456600
2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-(4-isothiocyanato-phenyl)-propionic acid
   Show/Hide
C38H37N5O6S
 1
1
IC50 > 10000 nM
   TI
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   TS
CP0538351
2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(4-isothiocyanato-phenyl)-propionylamino]-3-phenyl-propionic acid
   Show/Hide
C38H37N5O6S
 1
1
IC50 > 10000 nM
   TI
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CP0723478
2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-(4-amino-phenyl)-propionic acid
   Show/Hide
C37H39N5O6
 1
1
IC50 > 10000 nM
   TI
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   TS
CP0786258
2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(4-amino-phenyl)-propionylamino]-3-phenyl-propionic acid
   Show/Hide
C37H39N5O6
 1
1
IC50 > 10000 nM
   TI
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CP0043354
2-[2-({(S)-2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-4-methyl-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-phenyl-propionic acid
   Show/Hide
C37H38N4O6
 1
1
IC50 = 22700 nM
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CP0369775
ETORPHINE
   Show/Hide
C25H33NO4
 2
1
Ki = 0.14 nM
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2
Ki > 1000 nM
   TI
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CP0440275
(3R)-4-[[2-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C62H101N23O14
 1
1
Ki = 0.22 nM
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CP0460731
(3R)-4-[[2-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C74H124N26O16
 1
1
Ki = 0.26 nM
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CP0448454
(3R,6R,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
   Show/Hide
C62H99N23O13
 1
1
Ki = 0.52 nM
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CP0438950
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]-methylamino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C61H100N22O12
 1
1
Ki = 1.03 nM
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CP0406962
(3R,6R,12R)-N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C74H122N26O15
 1
1
Ki = 1.17 nM
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CP0047082
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C63H104N22O12
 2
1
Ki = 1.85 nM
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2
Ki = 1.91 nM
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CP0293493
(2S)-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxamide
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C75H127N25O14
 1
1
Ki = 1.88 nM
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CP0488976
(3R)-4-[[(2S)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C63H103N23O14
 1
1
Ki = 2.02 nM
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CP0463642
(3R,6R,9S,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-(1H-indol-3-ylmethyl)-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
   Show/Hide
C71H106N24O13
 1
1
Ki = 2.09 nM
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CP0859808
(5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide
   Show/Hide
C63H100N22O12
 1
1
Ki = 2.33 nM
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CP0880018
(5S,8S,13R,E)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide
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C63H100N22O12
 1
1
Ki = 2.33 nM
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CP0511642
(3R,6R,9S,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
   Show/Hide
C63H101N23O13
 1
1
Ki = 2.52 nM
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CP0382377
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-2-methyl-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C61H100N22O12
 1
1
Ki = 3.24 nM
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CP0429067
(3R)-4-[[(2S)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C71H108N24O14
 1
1
Ki = 3.41 nM
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CP0148509
DYNORPHIN A (1-11)
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C63H103N21O13
 1
1
Ki = 3.5 nM
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CP0407002
(3R,6R,9R,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C63H101N23O13
 1
1
Ki = 3.89 nM
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CP0440935
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C60H98N22O12
 1
1
Ki = 4.2 nM
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CP0394572
(3R)-4-[[(2R)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C63H103N23O14
 1
1
Ki = 4.21 nM
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CP0463043
(3R)-4-[[(2R)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
   Show/Hide
C71H108N24O14
 1
1
Ki = 4.57 nM
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CP0374752
(3R,6R,9R,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-(1H-indol-3-ylmethyl)-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C71H106N24O13
 1
1
Ki = 7.27 nM
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CP0487716
3-[(dimethylamino)methyl]-4-hydroxy-N,4-diphenylpiperidine-1-carboxamide;hydrochloride
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C21H28ClN3O2
 1
1
Ki = 7.3 nM
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CP0382612
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]acetamide
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C32H38N2O4
 1
1
Ki = 8.6 nM
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CP0567441
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-(4-piperidin-1-ylphenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
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C35H44N2O3
 1
1
Ki = 9.6 nM
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CP0463519
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-4-phenylbutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C61H100N22O12
 1
1
Ki = 13.7 nM
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CP0533460
N-(3-chlorophenyl)-3-[(dimethylamino)methyl]-4-hydroxy-4-phenylpiperidine-1-carboxamide;hydrochloride
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C21H27Cl2N3O2
 1
1
Ki = 14.1 nM
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CP0532486
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]-N',N'-dimethylethane-1,2-diamine
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C34H45N3O3
 1
1
Ki = 15.9 nM
   TI
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CP0389222
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C64H106N22O12
 1
1
Ki = 16.4 nM
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CP0445820
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]formamide
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C31H36N2O4
 1
1
Ki = 18.6 nM
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CP0445422
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C64H106N22O12
 1
1
Ki = 19.8 nM
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CP0402129
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]-2-phenylacetamide
   Show/Hide
C38H42N2O4
 1
1
Ki = 25.96 nM
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CP0404175
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C62H100N22O12
 1
1
Ki = 32.9 nM
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CP0860628
(2S,5S,8S,13S,E)-13-((S)-2-(2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)acetamido)-3-phenylpropanamido)-N-((S)-1-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidin-1-yl)-5-guanidino-1-oxopentan-2-yl)-2,5-bis(3-guanidinopropyl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide
   Show/Hide
C59H92N22O12
 1
1
Ki = 36 nM
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CP0479103
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[4-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
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C38H49N3O3
 1
1
Ki = 36.1 nM
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CP0401520
(2R)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C71H112N22O12
 1
1
Ki = 36.5 nM
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CP0466725
2-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]anilino]acetamide
   Show/Hide
C32H39N3O4
 1
1
Ki = 40.5 nM
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CP0407043
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C72H111N23O12
 1
1
Ki = 42.7 nM
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CP0402124
ethyl 3-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]anilino]propanoate
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C35H44N2O5
 1
1
Ki = 44.4 nM
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CP0491270
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C68H106N22O12
 1
1
Ki = 44.8 nM
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CP0401521
(2R)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C70H110N22O12
 1
1
Ki = 45.1 nM
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CP0383359
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C72H111N23O12
 1
1
Ki = 45.9 nM
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CP0402123
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]aniline
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C30H36N2O3
 1
1
Ki = 45.9 nM
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CP0401518
(2R)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C67H104N22O12
 1
1
Ki = 46.1 nM
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CP0418861
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-4-phenylbutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
   Show/Hide
C61H100N22O12
 1
1
Ki = 47 nM
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CP0498441
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C71H112N22O12
 1
1
Ki = 49.9 nM
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CP0439122
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C67H104N22O12
 1
1
Ki = 51.2 nM
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CP0559030
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-(4-piperazin-1-ylphenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
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C34H43N3O3
 1
1
Ki = 55.4 nM
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CP0445818
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]-N',N'-dimethylpropane-1,3-diamine
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C35H47N3O3
 1
1
Ki = 64.2 nM
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CP0879737
PhCH2Tyr-Gly-Gly-Phe-Leu-Arg-N-MeArg7-D-Ala8-Arg-D-Pro10-LysNH2
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C68H106N22O12
 1
1
Ki = 69.8 nM
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CP0445819
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-N-methylaniline
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C31H38N2O3
 1
1
Ki = 71 nM
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CP0401516
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C70H110N22O12
 1
1
Ki = 84.9 nM
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CP0436644
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C62H100N22O12
 1
1
Ki = 88.3 nM
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CP0859806
(2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)acetamido)-3-phenylpropanamido)-N-((S)-1-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidin-1-yl)-5-guanidino-1-oxopentan-2-yl)-2,5-bis(3-guanidinopropyl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide
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C59H92N22O12
 1
1
Ki = 93 nM
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CP0310470
(2S)-6-amino-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid
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C70H109N21O13
 1
1
Ki = 98.1 nM
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CP0549043
1-[4-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]piperazin-1-yl]ethanone
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C36H45N3O4
 1
1
Ki = 100.2 nM
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CP0450717
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-N-ethylaniline
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C32H40N2O3
 1
1
Ki = 105.8 nM
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CP0402126
N-(cyclopropylmethyl)-4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]aniline
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C34H42N2O3
 1
1
Ki = 115.3 nM
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CP0182171
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C60H98N22O12
 1
1
Ki = 123 nM
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CP0380412
(3R,8R,11R,14S)-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-11-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-2,5,10,13-tetraoxo-1,6,9,12-tetrazabicyclo[12.3.0]heptadecane-8-carboxamide
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C65H103N23O13
 1
1
Ki = 125 nM
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CP0401710
(2S)-1-[(2S)-2-[[2-acetamido-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C69H107N23O13
 1
1
Ki = 157 nM
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CP0501009
(2S)-6-amino-2-[[(2R)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid
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C70H109N21O13
 1
1
Ki = 159 nM
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CP0519315
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-(4-pyrrolidin-1-ylphenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
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C34H42N2O3
 1
1
Ki = 165.4 nM
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CP0880017
(5S,8S,13S,E)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide
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C63H100N22O12
 1
1
Ki = 180 nM
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CP0380061
(3S)-2-[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
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C61H98N22O12
 1
1
Ki = 206 nM
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CP0519314
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-N-propylaniline
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C33H42N2O3
 1
1
Ki = 274.9 nM
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CP0392269
methyl (2R,4aR,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(2,5-dibromofuran-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
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C23H26Br2O8
 1
1
Ki = 318 nM
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CP0445821
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]benzamide
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C37H40N2O4
 1
1
Ki = 321.3 nM
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CP0501076
(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-1,3-dihydroindene-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C61H98N22O12
 1
1
Ki = 364 nM
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CP0571312
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-[4-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]phenyl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
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C41H49N3O5S
 1
1
Ki = 499.7 nM
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CP0859807
(5S,8S,13S,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide
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C63H100N22O12
 1
1
Ki = 763 nM
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CP0416157
(4E,13S,16S)-16-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-N-[(2S)-5-carbamimidamido-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-5-carbamimidamido-1-[[(2S,3S)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-15-oxo-2,7-dioxa-14-azatricyclo[16.2.2.28,11]tetracosa-1(21),4,8,10,18(22),19,23-heptaene-13-carboxamide
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C80H125N25O14
 1
1
Ki = 903 nM
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CP0416159
1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-prop-2-enoxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C79H125N25O13
 1
1
Ki = 1170 nM
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CP0439123
(2S)-1-[(3S,6S,9S,12S)-12-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-6-[(2S)-butan-2-yl]-9-[3-(diaminomethylideneamino)propyl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carbonyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C65H95N17O13
 1
1
Ki = 1190 nM
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CP0519826
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-prop-2-enoxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C79H125N25O13
 1
1
Ki = 1430 nM
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CP0465998
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-3-(4-prop-2-enoxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
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C79H125N25O13
 1
1
Ki = 1460 nM
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CP0174760
(6S,9S,12R)-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-12-[[(2S)-2-[[2-[[2-[[(2S)-3-(4-hydroxyphenyl)-2-(methylamino)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C59H93N23O13
 1
1
Ki = 1490 nM
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CP0401517
(2S)-N-[(2S)-1-[[(2S,3S)-1-[[(2S)-3-acetamido-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]butanediamide
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C67H100N18O14
 1
1
Ki = 1500 nM
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CP0499015
(N-alpha-benzyl)Tyr-Gly-Gly-Phe-D-Asn-Arg-Arg-Dap(Ac)-Arg-Pro-Lys-NH2
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C67H102N24O14
 1
1
Ki = 1660 nM
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CP0216880
Ac-Phe-Phe-Phe-Arg-Leu-Arg-Arg-D-Ala-Arg-Pro-Lys-NH2
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C73H115N25O12
 1
1
Ki = 1750 nM
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CP0445940
(4E,13S,16S)-16-acetamido-N-[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[(2S)-5-carbamimidamido-1-[[(2S,3S)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-15-oxo-2,7-dioxa-14-azatricyclo[16.2.2.28,11]tetracosa-1(21),4,8,10,18(22),19,23-heptaene-13-carboxamide
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C80H125N25O14
 1
1
Ki = 1920 nM
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CP0401711
(2R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]butanediamide
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C68H105N23O13
 1
1
Ki = 2440 nM
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CP0224369
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-6,9-bis[3-(diaminomethylideneamino)propyl]-N-[(2S)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C62H90N20O13
 1
1
Ki = 2550 nM
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CP0224371
(2S,5S,15S)-15-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2,5-bis[3-(diaminomethylideneamino)propyl]-3,6,13,16-tetraoxo-1,4,7,12-tetrazacyclohexadecane-8-carboxamide
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C67H101N23O13
 1
1
Ki = 2610 nM
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CP0350244
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-2-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C66H99N23O13
 1
1
Ki = 3200 nM
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CP0411087
(4E,7S,10S,13S)-13-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-10-[3-(diaminomethylideneamino)propyl]-9,12-dioxo-2-oxa-8,11-diazabicyclo[13.2.2]nonadeca-1(17),4,15,18-tetraene-7-carboxamide
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C70H105N21O12
 1
1
Ki = 3460 nM
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CP0095956
zyklophin
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C65H96N20O13
 2
1
Ki = 4380 nM
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2
Ki = 5880 nM
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CP0231547
(2S,5S,15R)-15-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2,5-bis[3-(diaminomethylideneamino)propyl]-3,6,13,16-tetraoxo-1,4,7,12-tetrazacyclohexadecane-8-carboxamide
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C67H101N23O13
 1
1
Ki = 8260 nM
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CP0146444
(6S,9S,12R)-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-12-[[(2S)-2-[[2-[[2-[[(2S)-3-(4-hydroxyphenyl)-2-(2-phenylethylamino)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C66H99N23O13
 1
1
Ki = 8470 nM
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CP0085967
7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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C27H29NO3
 1
1
Ki > 10000 nM
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CP0122977
21-nitro-7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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C27H28N2O5
 1
1
Ki > 10000 nM
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CP0181621
8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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C27H29NO3
 1
1
Ki > 10000 nM
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CP0214836
21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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C27H28N2O5
 1
1
Ki > 10000 nM
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CP0268749
22-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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C27H28N2O5
 1
1
Ki > 10000 nM
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CP0281227
22-nitro-7apha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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C27H28N2O5
 1
1
Ki > 10000 nM
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CP0106313
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C59H93N23O12
 1
1
Ki > 10000 nM
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CP0231546
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-9-[3-(diaminomethylideneamino)propyl]-6-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C62H90N20O13
 1
1
Ki > 10000 nM
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CP0428348
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]propanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C59H93N23O13
 1
1
Ki > 10000 nM
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CP0093262
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-benzamido-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C65H95N23O14
 1
1
Ki = 10600 nM
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CP0064901
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(cyclopropylmethylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C62H97N23O13
 1
1
Ki = 10900 nM
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CP0146443
(6S,9S,12R)-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6,9-bis[3-(diaminomethylideneamino)propyl]-12-[[(2S)-2-[[2-[[2-[[(2S)-3-(4-hydroxyphenyl)-2-(prop-2-enylamino)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C61H95N23O13
 1
1
Ki = 11000 nM
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CP0231826
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-phenylpropanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-6,9-bis[3-(diaminomethylideneamino)propyl]-N-[(2S)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C62H90N20O12
 1
1
Ki = 11300 nM
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CP0350243
(6S,9S,12R)-12-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-6-[3-(diaminomethylideneamino)propyl]-9-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide
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C62H90N20O13
 1
1
Ki = 11500 nM
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CP0036843
(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester
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C23H28O8
 1
1
Ki > 1000 nM
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CP0040101
2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide
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C19H26Cl2N2O
 1
1
Ki > 1000 nM
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   TS
CP0372905
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(1-ethoxyethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372906
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(2-methoxypropan-2-yloxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372907
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(phenylmethoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C29H34O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372908
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-[(2-methylpropan-2-yl)oxymethoxy]-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C26H36O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372909
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(propan-2-yloxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372910
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(methylsulfanylmethoxy)-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C23H30O7S
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0395483
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(ethoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C24H32O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0395485
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C23H30O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0399581
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(2-fluoroethoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C24H31FO8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0405101
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(propoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0405102
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(fluoromethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C22H27FO7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0433117
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(oxan-2-yloxy)-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C26H34O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0433118
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(2-methoxyethoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0433119
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2,2,2-trifluoroethoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C24H29F3O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0452799
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2-trimethylsilylethoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C27H40O8Si
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0452800
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(butoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C26H36O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0845069
salvinorin B 1-ethoxyethyl ether
   Show/Hide
C25H35ClO8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0139686
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C21H30O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0214838
(2S,4aR,6aR,7R,9S,10aS,10bR)-dimethyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2,7-dicarboxylate
   Show/Hide
C21H28O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0323771
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(ethoxymethyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C22H32O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0323885
(2S,4aR,6aR,7R,9S,10aS,10bR)-2-isopropyl 7-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2,7-dicarboxylate
   Show/Hide
C23H32O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372800
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(pyrazine-2-carbonyl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C24H28N2O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372807
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(2-bromofuran-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C23H27BrO8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0372808
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-((S)-furan-2-yl(hydroxy)methyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C24H30O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0373868
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(acetoxymethyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C22H30O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0391771
12-epi-Salvinorin A
   Show/Hide
C23H28O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0406037
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(thiophene-2-carbonyl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C24H28O8S
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0414180
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(2-vinylfuran-3-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C25H30O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0423234
(2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2,7-dicarboxylate
   Show/Hide
C22H30O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0467297
(2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-7-(methoxycarbonyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2-carboxylic acid
   Show/Hide
C20H26O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0067334
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)-4,10-dioxo-dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C22H28N2O8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0415137
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-2-(1-methyl-1H-1,2,3-triazol-4-yl)-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C22H29N3O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0415138
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1-benzyl-1H-1,2,3-triazol-4-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C28H33N3O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0435054
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C21H27N3O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0459737
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1-(pivaloyloxymethyl)-1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C27H37N3O9
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0459760
(2S,4aS,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C21H27N3O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0500818
(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1-ethyl-1H-1,2,3-triazol-4-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C23H31N3O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0130404
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
   Show/Hide
C21H26O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0380446
methyl (2S,4aS,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-[2-(2-iodoethoxy)ethyl]-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C27H37IO8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0380447
methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-9-ethyl-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0380493
methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,9,10b-trimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C24H32O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0380494
methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,9,10b-trimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C24H32O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0401020
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-[2-(2-iodoethoxy)ethyl]-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C27H37IO8
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0401022
methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-prop-2-enyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C26H34O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0401025
methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-prop-2-enyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C26H34O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0415580
methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-propyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C26H36O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0429093
methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(5-iodopentyl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C28H39IO7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0434780
methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-9-ethyl-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C25H34O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0458417
methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-propyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C26H36O7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0477238
methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(5-iodopentyl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate
   Show/Hide
C28H39IO7
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0402125
[4-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]piperazin-1-yl]-phenylmethanone
   Show/Hide
C41H47N3O4
 1
1
Ki > 5000 nM
   TI
   LI
   LO
   TS
CP0450716
4-[[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]diazenyl]phenol
   Show/Hide
C36H39N3O4
 1
1
Ki > 5000 nM
   TI
   LI
   LO
   TS