| Compound ID |
Compound Name |
Compound Formula |
|
CP0443958
|
N-[2-(7-bromonaphthalen-1-yl)ethyl]-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C24H28BrN3O3S
|
1
|
| 1 |
IC50 = 0.17 nM
|
|
|
|
CP0429261
|
N-[2-(7-fluoronaphthalen-1-yl)ethyl]-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C24H28FN3O3S
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
|
CP0385967
|
N-[2-(7-bromonaphthalen-1-yl)-2-methylpropyl]-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C26H32BrN3O3S
|
1
|
| 1 |
IC50 = 0.31 nM
|
|
|
|
CP0459449
|
N-[2-(4-fluoronaphthalen-1-yl)ethyl]-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C24H28FN3O3S
|
1
|
| 1 |
IC50 = 0.46 nM
|
|
|
|
CP0429260
|
4-methoxy-N-[2-(7-methoxynaphthalen-1-yl)ethyl]-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C25H31N3O4S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0452675
|
N-[2-(7-fluoronaphthalen-1-yl)ethyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C23H26FN3O3S
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0567537
|
4-methoxy-3-(4-methylpiperazin-1-yl)-N-(2-naphthalen-1-ylethyl)benzenesulfonamide
Show/Hide
|
C24H29N3O3S
|
1
|
| 1 |
IC50 = 0.92 nM
|
|
|
|
CP0508526
|
4-methoxy-N-[2-(7-methoxynaphthalen-1-yl)ethyl]-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C24H29N3O4S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0385966
|
4-methoxy-N-[2-(7-methoxynaphthalen-1-yl)-2-methylpropyl]-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C26H33N3O4S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0452677
|
N-[[1-(7-bromonaphthalen-1-yl)cyclopropyl]methyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H28BrN3O3S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0420237
|
N-[2-(6-fluoronaphthalen-1-yl)ethyl]-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C24H28FN3O3S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0547560
|
4-methoxy-N-(2-methyl-2-naphthalen-1-ylpropyl)-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H31N3O3S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0547561
|
4-methoxy-N-[2-(7-methoxynaphthalen-1-yl)-2-methylpropyl]-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C27H35N3O4S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0573140
|
N-[2-(4-fluoronaphthalen-1-yl)ethyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C23H26FN3O3S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0573138
|
N-[2-(7-bromonaphthalen-1-yl)-2-methylpropyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H30BrN3O3S
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0905751
|
1-(Benzenesulfonyl)-5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)indole
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0429264
|
4-methoxy-3-(4-methylpiperazin-1-yl)-N-[(1-naphthalen-1-ylcyclopropyl)methyl]benzenesulfonamide
Show/Hide
|
C26H31N3O3S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0429262
|
N-[2-(7-bromonaphthalen-1-yl)ethyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C23H26BrN3O3S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0452676
|
4-methoxy-N-[[1-(7-methoxynaphthalen-1-yl)cyclopropyl]methyl]-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C27H33N3O4S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0389532
|
N-[[1-(7-fluoronaphthalen-1-yl)cyclopropyl]methyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H28FN3O3S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0566398
|
4-methoxy-N-[2-(4-methoxynaphthalen-1-yl)ethyl]-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C25H31N3O4S
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0389533
|
4-methoxy-N-(2-naphthalen-1-ylethyl)-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C23H27N3O3S
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0547562
|
N-[[1-(6-fluoronaphthalen-1-yl)cyclopropyl]methyl]-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C26H30FN3O3S
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0443959
|
4-methoxy-N-[(1-naphthalen-1-ylcyclopropyl)methyl]-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H29N3O3S
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0516652
|
N-[2-(6-fluoronaphthalen-1-yl)ethyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C23H26FN3O3S
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0459448
|
4-methoxy-N-[[1-(7-methoxynaphthalen-1-yl)cyclopropyl]methyl]-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C26H31N3O4S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0566397
|
4-methoxy-N-[2-(4-methoxynaphthalen-1-yl)ethyl]-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C24H29N3O4S
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0429263
|
N-[2-(6-fluoronaphthalen-1-yl)-2-methylpropyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H30FN3O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0572095
|
4-methoxy-N-[2-(5-methoxynaphthalen-1-yl)ethyl]-3-(4-methylpiperazin-1-yl)benzenesulfonamide
Show/Hide
|
C25H31N3O4S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0508527
|
N-[[1-(6-fluoronaphthalen-1-yl)cyclopropyl]methyl]-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C25H28FN3O3S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0886831
|
N-[2-Methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl]benzenesulfonamide
Show/Hide
|
C20H21N3O2S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0516653
|
4-methoxy-N-[2-(5-methoxynaphthalen-1-yl)ethyl]-3-piperazin-1-ylbenzenesulfonamide
Show/Hide
|
C24H29N3O4S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
Show/Hide
|
C10H12N2O
|
4
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
| 3 |
Ki = 33 nM
|
|
|
| 4 |
Ki = 61 nM
|
|
|
|
CP0078746
|
1-(2-bromophenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole
Show/Hide
|
C20H22BrN3O2S
|
1
|
| 1 |
IC50 = 135.1 nM
|
|
|
|
CP0058302
|
1-(benzenesulfonyl)-4-[(4-methylpiperazin-1-yl)methyl]indole
Show/Hide
|
C20H23N3O2S
|
1
|
| 1 |
IC50 = 233.5 nM
|
|
|
|
CP0059145
|
1-(4-Fluorobenzenesulfonyl)-3-(4-methylpiperazin-1-yl)-1H-indole
Show/Hide
|
C19H20FN3O2S
|
1
|
| 1 |
IC50 = 292 nM
|
|
|
|
CP0218959
|
1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazin-1-yl)-1H-indole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0402960
|
5-Bromo-1-(3-chlorobenzenesulfonyl)-3-(4-methylpiperazin-1-yl)-1H-indole
Show/Hide
|
C19H19BrClN3O2S
|
1
|
| 1 |
IC50 = 322 nM
|
|
|
|
CP0076180
|
9-(benzenesulfonyl)-6-methoxy-N,N-dimethyl-1,2,3,4-tetrahydrocarbazol-3-amine
Show/Hide
|
C21H24N2O3S
|
1
|
| 1 |
IC50 = 457 nM
|
|
|
|
CP0231487
|
5-Bromo-1-(4-fluorobenzenesulfonyl)-3-(4-methylpiperazin-1-yl)-1H-indole
Show/Hide
|
C19H19BrFN3O2S
|
1
|
| 1 |
IC50 = 1528 nM
|
|
|
|
CP0379693
|
5-Chloro-1-(4-fluorobenzenesulfonyl)-3-(4-ethylpiperazin-1-yl)-1H-indole
Show/Hide
|
C20H21ClFN3O2S
|
1
|
| 1 |
IC50 = 1783 nM
|
|
|
|
CP0148435
|
N,N-dimethyl-9-[3-(trifluoromethyl)phenyl]sulfonyl-1,2,3,4-tetrahydrocarbazol-3-amine
Show/Hide
|
C21H21F3N2O2S
|
1
|
| 1 |
IC50 = 1951 nM
|
|
|
|
CP0148433
|
9-(benzenesulfonyl)-6-bromo-N,N-dimethyl-1,2,3,4-tetrahydrocarbazol-3-amine
Show/Hide
|
C20H21BrN2O2S
|
1
|
| 1 |
IC50 = 2056 nM
|
|
|
|
CP0795225
|
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
|
C19H16N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0486512
|
N-(3-chloro-5-hydroxyphenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H21ClN4O3S
|
2
|
| 1 |
Kd = 0.05012 nM
|
|
|
| 2 |
Ki = 6.1 nM
|
|
|
|
CP0386122
|
N'-ethyl-N-(1H-indol-5-ylsulfonyl)-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C18H23N5O2S
|
2
|
| 1 |
Kd = 0.3162 nM
|
|
|
| 2 |
Ki = 4.8 nM
|
|
|
|
CP0534654
|
N-(4-amino-3-chlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H20ClN5O2S
|
2
|
| 1 |
Kd = 0.7943 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0542123
|
N-(4-amino-3-chlorophenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H22ClN5O2S
|
2
|
| 1 |
Kd = 1 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0503198
|
N-(3,4-dichlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H18Cl2N4O2S
|
2
|
| 1 |
Kd = 1.259 nM
|
|
|
| 2 |
Ki = 7.9 nM
|
|
|
|
CP0504972
|
N'-ethyl-N-(1H-indol-5-ylsulfonyl)-2,3,8-triazaspiro[4.5]dec-3-ene-2-carboximidamide
Show/Hide
|
C18H24N6O2S
|
2
|
| 1 |
Kd = 1.585 nM
|
|
|
| 2 |
Ki = 11.6 nM
|
|
|
|
CP0044031
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-2,3,8-triazaspiro[4.5]dec-3-ene-2-carboximidamide
Show/Hide
|
C16H22ClN5O2S
|
2
|
| 1 |
Kd = 1.995 nM
|
|
|
| 2 |
Ki = 7.2 nM
|
|
|
|
CP0499220
|
N',4-diethyl-N-naphthalen-1-ylsulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H22N4O2S
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 5.6 nM
|
|
|
|
CP0497774
|
N-(4-aminophenyl)sulfonyl-N'-ethyl-2,3,8-triazaspiro[4.5]dec-3-ene-2-carboximidamide
Show/Hide
|
C16H24N6O2S
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 14.2 nM
|
|
|
|
CP0455503
|
N-(5-chlorothiophen-2-yl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C12H17ClN4O2S2
|
2
|
| 1 |
Kd = 3.162 nM
|
|
|
| 2 |
Ki = 4.1 nM
|
|
|
|
CP0409990
|
N'-ethyl-N-(4-hydroxyphenyl)sulfonyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H22N4O3S
|
2
|
| 1 |
Kd = 3.162 nM
|
|
|
| 2 |
Ki = 5.8 nM
|
|
|
|
CP0384551
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.5]dec-3-ene-2-carboximidamide
Show/Hide
|
C17H23ClN4O2S
|
2
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0420180
|
N-(4-aminophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H21N5O2S
|
2
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 7.2 nM
|
|
|
|
CP0474116
|
N-(4-aminophenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H23N5O2S
|
2
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0044027
|
N-(3-chlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H19ClN4O2S
|
2
|
| 1 |
Kd = 5.012 nM
|
|
|
| 2 |
Ki = 7.9 nM
|
|
|
|
CP0534597
|
N-(4-aminophenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.5]dec-3-ene-2-carboximidamide
Show/Hide
|
C17H25N5O2S
|
2
|
| 1 |
Kd = 5.012 nM
|
|
|
| 2 |
Ki = 7.1 nM
|
|
|
|
CP0534655
|
N-(2,3-dihydro-1H-indol-5-ylsulfonyl)-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C18H25N5O2S
|
2
|
| 1 |
Kd = 5.012 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0384558
|
N-(2-chlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H19ClN4O2S
|
2
|
| 1 |
Kd = 6.31 nM
|
|
|
| 2 |
Ki = 27.8 nM
|
|
|
|
CP0425971
|
N-(4-chlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H19ClN4O2S
|
2
|
| 1 |
Kd = 6.31 nM
|
|
|
| 2 |
Ki = 18.5 nM
|
|
|
|
CP0425972
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H21ClN4O2S
|
2
|
| 1 |
Kd = 6.31 nM
|
|
|
| 2 |
Ki = 6.4 nM
|
|
|
|
CP0499066
|
N-(3-chlorophenyl)sulfonyl-4-ethyl-N'-methyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C13H17ClN4O2S
|
2
|
| 1 |
Kd = 6.31 nM
|
|
|
| 2 |
Ki = 17.8 nM
|
|
|
|
CP0384553
|
N',4-diethyl-N-naphthalen-2-ylsulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H22N4O2S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 17.2 nM
|
|
|
|
CP0426672
|
N-(3-chloro-2-fluorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H18ClFN4O2S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 2.7 nM
|
|
|
|
CP0458840
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-(furan-2-yl)-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C16H17ClN4O3S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 8.2 nM
|
|
|
|
CP0478660
|
N-[(5-chloro-3-methyl-1-benzothiophen-2-yl)sulfinyl]-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C17H21ClN4OS2
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 8.5 nM
|
|
|
|
CP0498765
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-4-methyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C13H17ClN4O2S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0474117
|
N'-ethyl-N-(3-hydroxyphenyl)sulfonyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H22N4O3S
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 18.5 nM
|
|
|
|
CP0429479
|
N-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C13H17ClN6O2S2
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 7.9 nM
|
|
|
|
CP0455504
|
(3S)-N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H19ClN4O2S
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 9.3 nM
|
|
|
|
CP0499068
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-8-oxa-2,3-diazaspiro[4.5]dec-3-ene-2-carboximidamide
Show/Hide
|
C16H21ClN4O3S
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 71.1 nM
|
|
|
|
CP0420186
|
N-[2-chloro-4-[[N-ethyl-C-(4-ethyl-3,4-dihydropyrazol-2-yl)carbonimidoyl]sulfamoyl]phenyl]acetamide
Show/Hide
|
C16H22ClN5O3S
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 8.7 nM
|
|
|
|
CP0486510
|
N-(3-chloro-4-hydroxyphenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H21ClN4O3S
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 14.6 nM
|
|
|
|
CP0499065
|
N',4-diethyl-N-(3-fluorophenyl)sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H19FN4O2S
|
2
|
| 1 |
Kd = 12.59 nM
|
|
|
| 2 |
Ki = 17 nM
|
|
|
|
CP0554824
|
N'-ethyl-N-(1H-indazol-5-ylsulfonyl)-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C17H22N6O2S
|
2
|
| 1 |
Kd = 12.59 nM
|
|
|
| 2 |
Ki = 28.6 nM
|
|
|
|
CP0064467
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-4,4-dimethyl-3H-pyrazole-2-carboximidamide
Show/Hide
|
C14H19ClN4O2S
|
2
|
| 1 |
Kd = 15.85 nM
|
|
|
| 2 |
Ki = 24.1 nM
|
|
|
|
CP0499221
|
N-(benzenesulfonyl)-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H20N4O2S
|
2
|
| 1 |
Kd = 15.85 nM
|
|
|
| 2 |
Ki = 33.9 nM
|
|
|
|
CP0050582
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H19ClN4O2S
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 23.9 nM
|
|
|
|
CP0425973
|
N-(3,5-dichlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H18Cl2N4O2S
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 21.9 nM
|
|
|
|
CP0504973
|
N-(4-aminophenyl)sulfonyl-N'-ethyl-4,4-dimethyl-3H-pyrazole-2-carboximidamide
Show/Hide
|
C14H21N5O2S
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 20.6 nM
|
|
|
|
CP0384555
|
N',4-diethyl-N-[3-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C15H19F3N4O2S
|
2
|
| 1 |
Kd = 31.62 nM
|
|
|
| 2 |
Ki = 17.9 nM
|
|
|
|
CP0425975
|
N'-(3-chlorophenyl)sulfonyl-4-ethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C12H15ClN4O2S
|
2
|
| 1 |
Kd = 39.81 nM
|
|
|
| 2 |
Ki = 24.2 nM
|
|
|
|
CP0388809
|
N-(3-chlorophenyl)sulfonyl-4-ethyl-N'-propyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C15H21ClN4O2S
|
2
|
| 1 |
Kd = 50.12 nM
|
|
|
| 2 |
Ki = 14.6 nM
|
|
|
|
CP0458839
|
N-(benzenesulfonyl)-N'-ethyl-4,4-dimethyl-3H-pyrazole-2-carboximidamide
Show/Hide
|
C14H20N4O2S
|
2
|
| 1 |
Kd = 63.1 nM
|
|
|
| 2 |
Ki = 146.6 nM
|
|
|
|
CP0474114
|
N-(3-chloro-5-methoxyphenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C17H23ClN4O3S
|
2
|
| 1 |
Kd = 63.1 nM
|
|
|
| 2 |
Ki = 47.5 nM
|
|
|
|
CP0384557
|
N',4-diethyl-N-(3-methylphenyl)sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C15H22N4O2S
|
2
|
| 1 |
Kd = 79.43 nM
|
|
|
| 2 |
Ki = 27.4 nM
|
|
|
|
CP0458079
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C12H15ClN4O2S
|
2
|
| 1 |
Kd = 79.43 nM
|
|
|
| 2 |
Ki = 33.9 nM
|
|
|
|
CP0386121
|
N',4-diethyl-N-(1H-indol-6-ylsulfonyl)-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C16H21N5O2S
|
2
|
| 1 |
Kd = 79.43 nM
|
|
|
| 2 |
Ki = 31.6 nM
|
|
|
|
CP0384561
|
N-(3-chlorophenyl)sulfonyl-N',4,4-triethyl-3H-pyrazole-2-carboximidamide
Show/Hide
|
C16H23ClN4O2S
|
2
|
| 1 |
Kd = 100 nM
|
|
|
| 2 |
Ki = 49.9 nM
|
|
|
|
CP0425379
|
N',4-diethyl-N-(3-methoxyphenyl)sulfonyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C15H22N4O3S
|
2
|
| 1 |
Kd = 100 nM
|
|
|
| 2 |
Ki = 26.6 nM
|
|
|
|
CP0426001
|
N-(2,5-dichlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H18Cl2N4O2S
|
2
|
| 1 |
Kd = 100 nM
|
|
|
| 2 |
Ki = 119.4 nM
|
|
|
|
CP0420183
|
N-(3-aminophenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C16H23N5O2S
|
2
|
| 1 |
Kd = 100 nM
|
|
|
| 2 |
Ki = 97.2 nM
|
|
|
|
CP0384552
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-pyridin-4-yl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C17H18ClN5O2S
|
2
|
| 1 |
Kd = 125.89 nM
|
|
|
| 2 |
Ki = 321.8 nM
|
|
|
|
CP0425969
|
N-(5-chloro-1,3-dimethylpyrazol-4-yl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C13H21ClN6O2S
|
2
|
| 1 |
Kd = 125.89 nM
|
|
|
| 2 |
Ki = 510.1 nM
|
|
|
|
CP0474115
|
N'-ethyl-N-(3-methoxyphenyl)sulfonyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C17H24N4O3S
|
2
|
| 1 |
Kd = 125.89 nM
|
|
|
| 2 |
Ki = 97.1 nM
|
|
|
|
CP0458842
|
N-(2,6-dichlorophenyl)sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C14H18Cl2N4O2S
|
2
|
| 1 |
Kd = 158.49 nM
|
|
|
| 2 |
Ki = 196.7 nM
|
|
|
|
CP0499069
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-(4-fluorophenyl)-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H18ClFN4O2S
|
2
|
| 1 |
Kd = 398.11 nM
|
|
|
| 2 |
Ki = 138.1 nM
|
|
|
|
CP0503195
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-5-methyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C13H17ClN4O2S
|
2
|
| 1 |
Kd = 794.33 nM
|
|
|
| 2 |
Ki = 231.1 nM
|
|
|
|
CP0534611
|
3-(4-aminophenyl)-N-(3-chlorophenyl)sulfonyl-N'-ethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H20ClN5O2S
|
2
|
| 1 |
Kd = 1584.89 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0375823
|
(3R)-N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H19ClN4O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0425448
|
N'-benzyl-N-(2-chlorophenyl)sulfonyl-4-ethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C19H21ClN4O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 92 nM
|
|
|
|
CP0425449
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-4,4-bis(fluoromethyl)-3H-pyrazole-2-carboximidamide
Show/Hide
|
C14H17ClF2N4O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 92 nM
|
|
|
|
CP0456115
|
N'-(2-chlorophenyl)sulfonyl-4-ethyl-N-phenyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H19ClN4O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0494749
|
N-(2-chlorophenyl)sulfonyl-4-ethyl-N'-propan-2-yl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C15H21ClN4O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0871707
|
N'-(3-Chlorophenylsulfonyl)-N,N-dimethyl-4-ethyl-4,5-dihydro-1H-pyrazole-1-carboxamidine
Show/Hide
|
C14H19ClN4O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0420175
|
N'-ethyl-N-(4-methoxyphenyl)sulfonyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C17H24N4O3S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 210.2 nM
|
|
|
|
CP0474118
|
N'-ethyl-4,4-dimethyl-N-[[2-(trifluoromethyl)-1H-indol-5-yl]sulfonyl]-3H-pyrazole-2-carboximidamide
Show/Hide
|
C17H20F3N5O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 160.2 nM
|
|
|
|
CP0474122
|
N-[4-(dimethylamino)phenyl]sulfonyl-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C16H25N5O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 205.9 nM
|
|
|
|
CP0486511
|
N-(3-chlorophenyl)sulfonyl-N'-ethyl-3-(4-hydroxyphenyl)-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C18H19ClN4O3S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 251.2 nM
|
|
|
|
CP0486513
|
N-(2,3-dihydro-1H-indol-6-ylsulfonyl)-N',4-diethyl-3,4-dihydropyrazole-2-carboximidamide
Show/Hide
|
C16H23N5O2S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki = 399.1 nM
|
|
|
|
CP0534614
|
N-(3-chloro-4-methoxyphenyl)sulfonyl-N'-ethyl-2,3-diazaspiro[4.4]non-3-ene-2-carboximidamide
Show/Hide
|
C17H23ClN4O3S
|
2
|
| 1 |
Kd > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0579145
|
US9974785, Example 3
Show/Hide
|
C19H18ClF2N3O2S
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0564436
|
US9974785, Example 2
Show/Hide
|
C19H18F3N3O2S
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
|
CP0214694
|
2-(2,6-difluorophenyl)-6-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]pyridazin-3-one
Show/Hide
|
C25H23F3N4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0564433
|
1-(3-fluorophenyl)sulfonyl-3-methyl-4-piperazin-1-ylindole
Show/Hide
|
C19H20FN3O2S
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0579146
|
US9974785, Example 5
Show/Hide
|
C19H18F3N3O2S
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0579713
|
US9974785, Example 6
Show/Hide
|
C19H18ClF2N3O2S
|
1
|
| 1 |
Ki = 0.68 nM
|
|
|
|
CP0217150
|
IDALOPIRDINE
Show/Hide
|
C20H19F5N2O
|
1
|
| 1 |
Ki = 0.83 nM
|
|
|
|
CP0037955
|
METHIOTHEPIN
Show/Hide
|
C20H24N2S2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0398689
|
N-methyl-1-(9-naphthalen-1-ylsulfonyl-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl)methanamine
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0414404
|
N-methyl-1-(3-naphthalen-1-ylsulfonyl-6,7-dihydrocyclobuta[e]indol-7-yl)methanamine
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0546202
|
US9974785, Example 4
Show/Hide
|
C19H18BrF2N3O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0514157
|
1,4-diazepan-1-yl-[1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindol-3-yl]methanone
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0414871
|
1-[3-(benzenesulfonyl)-6,7-dihydrocyclobuta[e]indol-7-yl]-N-methylmethanamine
Show/Hide
|
C18H18N2O2S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0564435
|
US9974785, Example 1
Show/Hide
|
C19H19F2N3O2S
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0326605
|
2-(2,5-difluorophenyl)-6-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]pyridazin-3-one
Show/Hide
|
C25H23F3N4O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0399598
|
2-[(4S,5R)-9-(benzenesulfonyl)-4-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0507414
|
1-(5-chloronaphthalen-1-yl)sulfonyl-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H28ClN3O3S
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0218398
|
6-[5-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]pentanoyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C28H30FN3O3
|
1
|
| 1 |
Ki = 5.55 nM
|
|
|
|
CP0915589
|
N'-(4-(Methylsulfonyl)phenylsulfonyl)-N,4-diethyl-4,5-dihydro-1H-pyrazole-1-carboxamidine
Show/Hide
|
C15H22N4O4S2
|
1
|
| 1 |
Ki < 6 nM
|
|
|
|
CP0554921
|
6-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]-1-hydroxybutyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C27H30FN3O3
|
1
|
| 1 |
Ki = 6.36 nM
|
|
|
|
CP0567319
|
US9974785, Example 7
Show/Hide
|
C20H21F2N3O2S
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0390843
|
[1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindol-3-yl]-piperazin-1-ylmethanone
Show/Hide
|
C24H25N3O4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0518747
|
1-(4-methoxynaphthalen-1-yl)sulfonyl-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C27H31N3O4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0466956
|
2-[(6R,7R)-3-(benzenesulfonyl)-7-(methylamino)-6,7-dihydrocyclobuta[e]indol-6-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0447467
|
2-[(4R,5R)-9-(benzenesulfonyl)-4-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0579144
|
US9974785, Example 11
Show/Hide
|
C19H19F2N3O2S
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0357219
|
2-(2,5-dichlorophenyl)-6-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]pyridazin-3-one
Show/Hide
|
C25H23Cl2FN4O3
|
1
|
| 1 |
Ki = 11.7 nM
|
|
|
|
CP0573970
|
US9974785, Example 8
Show/Hide
|
C20H21F2N3O3S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0408929
|
2-[(4S,5R)-9-(benzenesulfonyl)-4-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0546200
|
US9974785, Example 19
Show/Hide
|
C19H18BrF2N3O2S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0568902
|
US9974785, Example 13
Show/Hide
|
C19H18ClF2N3O2S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0577124
|
US9974785, Example 17
Show/Hide
|
C19H18F3N3O2S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0546199
|
US9974785, Example 18
Show/Hide
|
C19H18ClF2N3O2S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0568573
|
US9974785, Example 15
Show/Hide
|
C20H21F2N3O2S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0554920
|
6-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C27H30FN3O2
|
1
|
| 1 |
Ki = 17.7 nM
|
|
|
|
CP0514159
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-[4-(trifluoromethoxy)phenyl]sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C23H26F3N3O4S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0521335
|
N-[2-(diethylamino)ethyl]-1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H31N3O4S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0550404
|
US9974785, Example 14
Show/Hide
|
C19H18BrF2N3O2S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0390840
|
1-(4-methoxynaphthalen-1-yl)sulfonyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H29N3O4S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0406878
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-[4-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C23H26F3N3O3S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0436693
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C23H26F3N3O3S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0507415
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-naphthalen-2-ylsulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H29N3O3S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0399600
|
2-[(6S,7S)-3-(benzenesulfonyl)-6-(methylamino)-6,7-dihydrocyclobuta[e]indol-7-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0429622
|
6-[5-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]-1-hydroxypentyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C28H32FN3O3
|
1
|
| 1 |
Ki = 29.46 nM
|
|
|
|
CP0546197
|
US9974785, Example 12
Show/Hide
|
C19H18F3N3O2S
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0383631
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-naphthalen-1-ylsulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H29N3O3S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0507413
|
1-(4-methoxynaphthalen-1-yl)sulfonyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C28H31N3O4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0507420
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-(3-phenylphenyl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C28H31N3O3S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0514158
|
1-(2,3,3a,7a-tetrahydro-1-benzofuran-5-ylsulfonyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C24H31N3O4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0518764
|
1-(4-methoxynaphthalen-1-yl)sulfonyl-N-(3-morpholin-4-ylpropyl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C27H31N3O5S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0432198
|
2-[(4R,5R)-9-(benzenesulfonyl)-4-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0568903
|
US9974785, Example 20
Show/Hide
|
C19H18ClF2N3O2S
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0411081
|
N-(1-benzylpiperidin-4-yl)-1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C32H33N3O4S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0493558
|
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C24H29N3O5S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0451468
|
(10S,16R)-5-(benzenesulfonyl)-5,13-diazatetracyclo[7.7.0.02,6.010,16]hexadeca-1(9),2(6),3,7-tetraene
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0436691
|
[1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindol-3-yl]-[4-(3-methoxyphenyl)piperazin-1-yl]methanone
Show/Hide
|
C31H31N3O5S
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0507418
|
1-[(5-chloro-3-methyl-1-benzothiophen-2-yl)sulfonyl]-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C25H28ClN3O3S2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0564434
|
US9974785, Example 16
Show/Hide
|
C20H21F2N3O3S
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0390842
|
[3-(aminomethyl)azetidin-1-yl]-[1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindol-3-yl]methanone
Show/Hide
|
C24H25N3O4S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0390844
|
N-[3-(diethylamino)propyl]-1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C27H33N3O4S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0411082
|
N-(3-imidazol-1-ylpropyl)-1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H26N4O4S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0398688
|
N-[4-[2-[[3-(benzenesulfonyl)-6,7-dihydrocyclobuta[e]indol-7-yl]methyl-methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0401790
|
1-(4-methoxy-2,3-dimethylphenyl)sulfonyl-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C25H33N3O4S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0507419
|
1-(4-methoxy-2,3,6-trimethylphenyl)sulfonyl-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H35N3O4S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0508176
|
2-(2,3-dichlorophenyl)-6-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]pyridazin-3-one
Show/Hide
|
C25H23Cl2FN4O3
|
1
|
| 1 |
Ki = 113 nM
|
|
|
|
CP0436694
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-(4-phenylphenyl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C28H31N3O3S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0507417
|
1-(2,1,3-benzothiadiazol-4-ylsulfonyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C22H25N5O3S2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0471145
|
2-[(4S,5S)-9-(benzenesulfonyl)-5-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0390841
|
(3-aminoazetidin-1-yl)-[1-(4-methoxynaphthalen-1-yl)sulfonyl-2,3-dihydroindol-3-yl]methanone
Show/Hide
|
C23H23N3O4S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0399599
|
2-[(4S,5R)-9-(benzenesulfonyl)-5-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0466957
|
2-[(6R,7S)-3-(benzenesulfonyl)-6-(methylamino)-6,7-dihydrocyclobuta[e]indol-7-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0466962
|
(2R,8S)-12-(benzenesulfonyl)-5,12-diazatetracyclo[7.7.0.02,8.011,15]hexadeca-1(9),10,13,15-tetraene
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0377493
|
2-[(6S,7R)-3-(benzenesulfonyl)-7-(methylamino)-6,7-dihydrocyclobuta[e]indol-6-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0853339
|
1-{2-[2-(2,3-Dimethylphenoxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0317149
|
6-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butanoyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C27H28FN3O3
|
1
|
| 1 |
Ki = 241 nM
|
|
|
|
CP0411083
|
1-(benzenesulfonyl)-N-methyl-N-(1-methylpiperidin-4-yl)-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C22H27N3O3S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0436692
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-thiophen-2-ylsulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C20H25N3O3S2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0495880
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-(3-methylquinolin-8-yl)sulfonyl-2,3-dihydroindole-3-carboxamide
Show/Hide
|
C26H30N4O3S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0380756
|
2-[(4S,5R)-9-(benzenesulfonyl)-5-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0466960
|
2-[(4S,5S)-9-(benzenesulfonyl)-5-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
1
|
| 1 |
Ki = 1260 nM
|
|
|
|
CP0873149
|
1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
Ki = 1540 nM
|
|
|
|
CP0902025
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C25H38Cl2N2O2
|
1
|
| 1 |
Ki = 2155 nM
|
|
|
|
CP0864251
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
Ki = 2427 nM
|
|
|
|
CP0853338
|
1-[3-(Mesityloxy)propyl]-4-(4-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C23H34Cl2N2O2
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0864252
|
1-Benzyl-4-{2-[2-(mesityloxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O2
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0867161
|
1-[3-(2,4-Dimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride
Show/Hide
|
C22H31ClN2O2
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0873148
|
1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
Show/Hide
|
C20H27Cl3N2O
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0874185
|
2-(4-{2-[2-(2,3,5-Trimethylphenoxy)ethoxy]ethyl}piperazin-1-yl)ethanol dihydrochloride
Show/Hide
|
C19H34Cl2N2O3
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0907673
|
2-(4-{2-[2-(Mesityloxy)ethoxy]ethyl}piperazin-1-yl)ethanol dihydrochloride
Show/Hide
|
C19H34Cl2N2O3
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0245665
|
(R)-1-(2-(1-(3-methoxy-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl-4-methyl piperidine
Show/Hide
|
C19H30N2O3S
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
