Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N'-ethyl-N-(1H-indol-5-ylsulfonyl)-2,3,8-triazaspiro[4.5]dec-3-ene-2-carboximidamide
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 PubChem ID
CID: 44240860
SID: 85260785
Canonical SMILES
CCN\C(=N/S(=O)(=O)c1ccc2[nH]ccc2c1)N1CC2(CCNCC2)C=N1
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Compound Formula C18H24N6O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Kd = 1.585 nM
   TI
   LI
   LO
   TS
2
Ki = 11.6 nM
   TI
   LI
   LO
   TS