Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT00888 , Mast/stem cell growth factor receptor Kit
Gene Name KIT
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P10721
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT00888
 
Compound ID Compound Name Compound Formula
CP0448810
4-{6-Methoxy-7-[3-(4-methyl-piperidin-1-yl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-cyano-phenyl)-amide
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C30H37N7O3
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0430789
4-{6-Methoxy-7-[3-(2-methyl-piperidin-1-yl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-cyano-phenyl)-amide
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C30H37N7O3
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0380972
4-{6-Methoxy-7-[3-(2-methyl-piperidin-1-yl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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C32H44N6O4
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0374313
4-{6-Methoxy-7-[3-(4-methyl-piperidin-1-yl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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C32H44N6O4
 1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
CP0115223
4-[6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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C30H40N6O5
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0406454
4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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C30H40N6O4
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0034949
4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide
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C31H42N6O4
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0377709
4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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C26H33N5O5
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0002778
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
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C29H31N7O
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS