General Information of the Compound
| Compound ID |
CP0377709
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| Compound Name |
4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide
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| Structure |
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| Formula |
C26H33N5O5
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| Molecular Weight |
495.58
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| Canonical SMILES |
COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(OC(C)C)cc3)c2cc1OC
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| InChI |
InChI=1S/C26H33N5O5/c1-18(2)36-20-7-5-19(6-8-20)29-26(32)31-11-9-30(10-12-31)25-21-15-23(34-4)24(35-14-13-33-3)16-22(21)27-17-28-25/h5-8,15-18H,9-14H2,1-4H3,(H,29,32)
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| InChIKey |
IZVDXKIUMGJIMC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01008, Macrophage colony-stimulating factor 1 receptor
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT00844, Platelet-derived growth factor receptor beta
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3