Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide
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 PubChem ID
CID: 3038522
SID: 50086911
Canonical SMILES
COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1
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Compound Formula C31H42N6O4
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 170 nM
2 IC50 = 220 nM
3 Kd = 2.7 nM
4 Kd = 3.8 nM
5 Kd = 6 nM
6 Kd = 23 nM
7 Kd = 26 nM
8 Kd = 29 nM
9 Kd = 120 nM
10 Kd = 1100 nM