Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05330 , Multidrug and toxin extrusion protein 2
Gene Name SLC47A2
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q86VL8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT05330
 
Compound ID Compound Name Compound Formula
CP0000082
CAS_68647
   Show/Hide
C18H19N3O
 2
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
2
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0002778
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
C29H31N7O
 2
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
2
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0046285
(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine;hydrochloride
   Show/Hide
C22H30Cl2N10
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0002490
1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis(oxidanyl)anthracene-9,10-dione;hydrochloride
   Show/Hide
C22H28N4O6
 2
1
IC50 = 530 nM
   TI
   LI
   LO
   TS
2
IC50 = 830 nM
   TI
   LI
   LO
   TS
CP0014442
4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydroxyethanesulfonic acid
   Show/Hide
C19H24N4O2
 2
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
2
IC50 = 10400 nM
   TI
   LI
   LO
   TS
CP0052856
6-(2-{(2-Hydroxy-ethyl)-[3-(4-nitro-phenyl)-propyl]-amino}-ethylamino)-1,3-dimethyl-1H-pyrimidine-2,4-dione
   Show/Hide
C19H27N5O5
 2
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
2
IC50 = 6500 nM
   TI
   LI
   LO
   TS
CP0036175
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
   Show/Hide
C37H48N6O5S2
 2
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
2
IC50 = 23700 nM
   TI
   LI
   LO
   TS
CP0041351
2,2'-THIOBIS(4,6-DICHLOROPHENOL)
   Show/Hide
C12H6Cl4O2S
 1
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS
CP0045344
4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide
   Show/Hide
C31H33N3O6S
 1
1
IC50 = 7600 nM
   TI
   LI
   LO
   TS
CP0040838
(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide
   Show/Hide
C36H47N5O4
 1
1
IC50 = 7800 nM
   TI
   LI
   LO
   TS
CP0076378
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
   Show/Hide
C33H38N4O6
 2
1
IC50 = 7900 nM
   TI
   LI
   LO
   TS
2
IC50 = 78600 nM
   TI
   LI
   LO
   TS
CP0093295
(S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione; hydrochloride
   Show/Hide
C23H23N3O5
 1
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
CP0267175
4-(6-Guanidino-hexanoyloxy)-benzoic acid ethyl ester
   Show/Hide
C16H23N3O4
 1
1
IC50 = 10800 nM
   TI
   LI
   LO
   TS
CP0072808
7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((2R,5S,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide
   Show/Hide
C33H37N5O5
 1
1
IC50 = 12600 nM
   TI
   LI
   LO
   TS
CP0234575
US9199927, camostat
   Show/Hide
C20H22N4O5
 1
1
IC50 = 12700 nM
   TI
   LI
   LO
   TS
CP0077311
1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one
   Show/Hide
C22H24ClN5O2
 1
1
IC50 = 14800 nM
   TI
   LI
   LO
   TS
CP0045125
17-ethinyl-3,17-estradiol
   Show/Hide
C20H24O2
 1
1
IC50 = 20200 nM
   TI
   LI
   LO
   TS
CP0671751
Vecuronium Bromide
   Show/Hide
C34H57BrN2O4
 1
1
IC50 = 25200 nM
   TI
   LI
   LO
   TS
CP0018133
3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}-pyridin-2-yl-amino)-propionic acid
   Show/Hide
C25H25N7O3
 1
1
IC50 = 25300 nM
   TI
   LI
   LO
   TS
CP0308131
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine
   Show/Hide
C16H15N3
 1
1
IC50 = 29800 nM
   TI
   LI
   LO
   TS
CP0076561
3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
   Show/Hide
C8H15N7O2S3
 1
1
IC50 = 36200 nM
   TI
   LI
   LO
   TS
CP0040814
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
   Show/Hide
C19H21N5O4
 1
1
IC50 = 38400 nM
   TI
   LI
   LO
   TS
CP0050753
5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole
   Show/Hide
C16H15F2N3O4S
 1
1
IC50 = 43200 nM
   TI
   LI
   LO
   TS
CP0042717
(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
   Show/Hide
C21H31N5O2
 1
1
IC50 = 46000 nM
   TI
   LI
   LO
   TS
CP0418486
TUBOCURARINE
   Show/Hide
C37H41N2O6+
 1
1
IC50 = 55500 nM
   TI
   LI
   LO
   TS