Brief Information of the Compound and Protein
Compound Name
(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
    Show/Hide
PubChem ID
CID: 2477
SID: 14902734
Canonical SMILES
O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
    Show/Hide
Compound Formula C21H31N5O2
Compound Structure
Protein Name
Multidrug and toxin extrusion protein 2
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC47 family of multidrug and toxin extrusion transporters
Uniprot ID
Q86VL8
Gene Name
SLC47A2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 46000 nM
   TI
   LI
   LO
   TS