Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05029 , Neuromedin-K receptor
 Protein Info 
Gene Name TACR3
Organism Cavia porcellus, Guinea pig
Protein Classification Membrane receptor
Uniprot ID P30098
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT05029
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0074738
 Compound Info 
(S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
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C35H41Cl2N3O2
  5
1
Kd = 0.08 nM
 Bioactivity Info 
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2
Kd = 0.15 nM
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3
Kd = 3.162 nM
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4
Ki = 0.6 nM
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5
Ki = 0.8 nM
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CP0376631
 Compound Info 
2-(3,4-dichlorophenyl)-N-(4-fluoro-3-trifluoromethylbenzyl)-2,N-dimethyl-4-[4-(2-oxo-pyrrolidin-1-yl)-piperidin-1-yl]-butyramide
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C29H33Cl2F4N3O2
  3
1
Kd = 10.96 nM
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2
Ki = 1.6 nM
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3
Ki = 1.8 nM
 Bioactivity Info 
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CP0114970
 Compound Info 
(S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide
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C25H22N2O2
  4
1
Kd = 12.3 nM
 Bioactivity Info 
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2
Kd = 15.49 nM
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3
Ki = 3.8 nM
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4
Ki = 5 nM
 Bioactivity Info 
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CP0374063
 Compound Info 
4-[4-(acetylmethyl-amino)-piperidin-1-yl]-2-(3,4-dichlorophenyl)-N-(4-fluoro-3-trifluoromethylbenzyl)-2,N-dimethylbutyramide
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C28H33Cl2F4N3O2
  3
1
Kd = 14.79 nM
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2
Ki = 2.7 nM
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3
Ki = 3.5 nM
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CP0397341
 Compound Info 
4-[4-(acetylmethyl-amino)-piperidin-1-yl]-N-(2-chloro-benzyl)-2-(3,4-dichlorophenyl)-2,N-dimethylbutyramide
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C27H34Cl3N3O2
  4
1
Kd = 23.99 nM
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2
Kd = 29.51 nM
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3
Ki = 8 nM
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4
Ki = 11.9 nM
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