Brief Information of the Compound and Protein
Compound Name
4-[4-(acetylmethyl-amino)-piperidin-1-yl]-N-(2-chloro-benzyl)-2-(3,4-dichlorophenyl)-2,N-dimethylbutyramide
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PubChem ID
CID: 44550460
SID: 87233465
Canonical SMILES
CN(Cc1ccccc1Cl)C(=O)C(C)(CCN1CCC(CC1)N(C)C(C)=O)c1ccc(Cl)c(Cl)c1
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Compound Formula C27H34Cl3N3O2
Compound Structure
Protein Name
Neuromedin-K receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P30098
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
Kd = 23.99 nM
   TI
   LI
   LO
   TS
2
Kd = 29.51 nM
   TI
   LI
   LO
   TS
3
Ki = 8 nM
   TI
   LI
   LO
   TS
4
Ki = 11.9 nM
   TI
   LI
   LO
   TS