Brief Information of the Compound and Protein
Compound Name
(S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide
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PubChem ID
CID: 5311424
SID: 57304378
Canonical SMILES
CC[C@H](NC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1)c1ccccc1
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Compound Formula C25H22N2O2
Compound Structure
Protein Name
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P30098
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
Kd = 12.3 nM
   TI
   LI
   LO
   TS
2
Kd = 15.49 nM
   TI
   LI
   LO
   TS
3
Ki = 3.8 nM
   TI
   LI
   LO
   TS
4
Ki = 5 nM
   TI
   LI
   LO
   TS