Brief Information of the Compound and Protein
Compound Name
(S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
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PubChem ID
CID: 219077
SID: 57304375
Canonical SMILES
CN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1)c1ccccc1
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Compound Formula C35H41Cl2N3O2
Compound Structure
Protein Name
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P30098
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
Kd = 0.08 nM
   TI
   LI
   LO
   TS
2
Kd = 0.15 nM
   TI
   LI
   LO
   TS
3
Kd = 3.162 nM
   TI
   LI
   LO
   TS
4
Ki = 0.6 nM
   TI
   LI
   LO
   TS
5
Ki = 0.8 nM
   TI
   LI
   LO
   TS