N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide

6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-(oxolan-3-yloxy)quinoline-3-carbonitrile

6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-(oxolan-3-ylmethoxy)quinoline-3-carbonitrile

6,7-difluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carbonitrile

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-propan-2-yloxyquinoline-3-carbonitrile

6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carbonitrile

methyl 4-[3-[2-(4-acetamidophenyl)sulfanylacetyl]-2,5-dimethylpyrrol-1-yl]benzoate

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-(trideuteriomethoxy)quinoline-3-carbonitrile

7-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carbonitrile

8-cyclobutyloxy-4-[4-(2-fluorophenyl)piperazin-1-yl]quinoline-3-carbonitrile

US9212196, Derivative 20

US9212196, Derivative 6

8-(difluoromethoxy)-6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]quinoline-3-carbonitrile

US9212196, Derivative 28

US9212196, Derivative 8

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-imidazol-1-ylquinoline-3-carbonitrile

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-(2-methylmorpholin-4-yl)quinoline-3-carbonitrile

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine

3-(2-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

3-(3-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-hydroxyquinoline-3-carbonitrile

8-(4,4-difluoropiperidin-1-yl)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinoline-3-carbonitrile

8-cyclobutyloxy-6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]quinoline-3-carbonitrile

5-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carbonitrile

8-(difluoromethoxy)-4-[4-(2-fluorophenyl)piperazin-1-yl]quinoline-3-carbonitrile

6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-hydroxyquinoline-3-carbonitrile

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-pyrazol-1-ylquinoline-3-carbonitrile

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-(1,2,4-triazol-1-yl)quinoline-3-carbonitrile

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-pyrrolidin-1-ylquinoline-3-carbonitrile

4-[4-(2-fluorophenyl)piperazin-1-yl]-8-piperidin-1-ylquinoline-3-carbonitrile

US9212196, Derivative 24

US9212196, Derivative 7

US9212196, Derivative 3

US9212196, Derivative 2

US9212196, Derivative 26

US9212196, Derivative 22

US9212196, Derivative 25

US9212196, Derivative 32

US9212196, Derivative 9

3-[3-[(2-cyclopentyl-1-oxo-3H-isoindol-5-yl)oxymethyl]phenyl]-4-methoxybenzoic acid

2-chloro-5-[3-[(2-cyclopropyl-3-oxo-1,2-benzothiazol-6-yl)oxymethyl]phenyl]benzoic acid

US9212196, Derivative 14

US9212196, Derivative 21

US9212196, Derivative 12

(3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosphinyl]propenoic acid

US9212196, Derivative 10

US9212196, Derivative 19

US9212196, Derivative 23

(S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosphinic acid

(3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosphinyl]-2-chloropropanoic Acid

D-AP4

US9212196, Derivative 5

US9212196, Derivative 30

ethyl 8-methoxy-4-[5-methoxy-6-(2-methoxyphenyl)pyridin-3-yl]quinoline-3-carboxylate

ethyl 4-[6-(2-ethoxyphenyl)pyridin-3-yl]-8-methoxyquinoline-3-carboxylate

ethyl 8-methoxy-4-[6-(2-methylsulfanylphenyl)pyridin-3-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methylsulfanylphenyl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[5-(2-methoxyphenyl)pyrazin-2-yl]quinoline-3-carboxylate

2-(3,4-dimethoxyphenyl)-5-[2-imidazol-1-yl-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 8-methoxy-4-[6-(2-methoxyphenyl)pyridin-3-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinoline-3-carboxylate

6-(2,4-dimethylphenyl)-2-ethyl-6,7-dihydro-5H-1,3-benzoxazol-4-one

ethyl 6,8-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 4-[4-(2,6-dimethoxyphenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

ethyl 4-[6-(2-ethoxyphenyl)pyridin-3-yl]-6,8-dimethoxyquinoline-3-carboxylate

ethyl 6,8-dimethoxy-4-[6-(2-methoxyphenyl)pyridin-3-yl]quinoline-3-carboxylate

4-[2-[5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-(trifluoromethoxy)phenyl]morpholine

ethyl 8-methoxy-4-[1-[(2-methoxyphenyl)methyl]pyrrol-3-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methoxyphenyl)-3-methylpiperazin-1-yl]quinoline-3-carboxylate

2-[4-(cyclopropylmethoxy)-3-methoxyphenyl]-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3,4-dimethoxyphenyl)-5-[2-(2-methylpyrazol-3-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

3-(3,4-dimethoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole

ethyl 8-methoxy-4-[4-(2-methoxypyridin-3-yl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methoxyphenyl)-2-methylpiperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[6-(2-propan-2-yloxyphenyl)pyridin-3-yl]quinoline-3-carboxylate

2-(4-cyclobutyloxy-3-methoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3,4-dimethoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 4-[4-(2,4-dimethoxyphenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

2-(3,4-dimethoxyphenyl)-5-[2-pyrazol-1-yl-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

5-(3,4-dimethoxyphenyl)-2-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3-oxazole

ethyl 4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

ethyl 4-[5-fluoro-2-methoxy-6-(2-methoxyphenyl)pyridin-3-yl]-8-methoxyquinoline-3-carboxylate

2-(3,4-dimethoxyphenyl)-5-[2-(1H-pyrazol-4-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 8-methoxy-4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]quinoline-3-carboxylate

5-(3,4-dimethoxyphenyl)-3-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole

ethyl 8-methoxy-4-[2-(2-methoxyphenyl)pyrimidin-5-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[5-(2-methoxyphenyl)pyridin-2-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methoxyphenyl)phenyl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(3-methoxypyrazin-2-yl)piperazin-1-yl]quinoline-3-carboxylate

2-(3,4-dimethoxyphenyl)-5-[2-(1,3-thiazol-4-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 8-methoxy-4-[1-(2-methoxyphenyl)-3,6-dihydro-2H-pyridin-4-yl]quinoline-3-carboxylate

ethyl 4-[4-(2-cyanophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

ethyl 4-[4-(2-methoxyphenyl)piperazin-1-yl]pyridine-3-carboxylate

2-(5,6-dimethoxypyridin-3-yl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 8-methoxy-4-[2-(2-methoxy-N-methylanilino)ethyl-methylamino]quinoline-3-carboxylate

ethyl 7-[4-(2-methoxyphenyl)piperazin-1-yl]thieno[3,2-b]pyridine-6-carboxylate

ethyl 4-[4-(2-methoxyphenyl)piperazin-1-yl]thieno[2,3-b]pyridine-5-carboxylate

ethyl 4-[4-(2-ethoxyphenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

2-(3,4-dimethoxyphenyl)-5-[2-piperidin-1-yl-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 4-[4-(2-fluorophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

4-(3,4-dimethoxyphenyl)-2-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3-oxazole

2-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-5-(2-fluoro-4,5-dimethoxyphenyl)-1,3,4-oxadiazole

2-(3,4-dimethoxyphenyl)-5-(2-(pyridazin-4-yl)-5-(trifluoromethoxy)phenyl)-1,3,4-oxadiazole

5-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazole

2-(3,4-dimethoxyphenyl)-5-(2-(pyridin-4-yl)-5-(trifluoromethoxy)phenyl)-1,3,4-oxadiazole

1-(2-(4-(3,4-dimethoxyphenyl)-1H-imidazol-2-yl)-4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole

2-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-5-(2-methoxypyridin-4-yl)-1,3,4-oxadiazole

1-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(3,4-dimethoxyphenyl)-1H-1,2,3-triazole

ethyl 8-methoxy-4-[1-(2-methoxyphenyl)piperidin-4-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[2-(2-methoxyphenyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methylphenyl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[6-(2-methoxyphenyl)-6-azabicyclo[3.1.1]heptan-3-yl]quinoline-3-carboxylate

7-(4-fluorophenyl)-2-[[2-(trifluoromethyl)pyridin-4-yl]oxymethyl]pyrazolo[1,5-a]pyrimidine-5-carboxamide

2-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]-7-(4-fluorophenyl)thieno[3,2-b]pyridine-5-carboxamide

2-(3,4-dimethoxyphenyl)-5-[2-pyrrolidin-1-yl-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(2,3-difluoro-4-methoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(2,2-difluoro-1,3-benzodioxol-5-yl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3,4-dimethoxyphenyl)-5-[2-(1-methylpyrazol-4-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3,4-dimethoxyphenyl)-5-[2-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3,4-dimethoxyphenyl)-5-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(4-fluoro-3-methoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(1,3-benzodioxol-5-yl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3-fluoro-4,5-dimethoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(6-methoxypyridin-3-yl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

2-(3-fluoro-4-methoxyphenyl)-5-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]-1,3,4-oxadiazole

ethyl 5-methoxy-1-[4-(2-methoxyphenyl)piperazin-1-yl]naphthalene-2-carboxylate

ethyl 4-[4-(2-methoxyphenyl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(1,3-thiazol-5-yl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[6-(2-methoxyphenyl)-2,6-diazaspiro[3.3]heptan-2-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-[3-(2-methoxyphenyl)-3-azabicyclo[3.1.1]heptan-6-yl]quinoline-3-carboxylate

ethyl 4-[4-(2-chlorophenyl)piperazin-1-yl]-8-methoxyquinoline-3-carboxylate

ethyl 8-methoxy-4-[4-(2-methylpyrazol-3-yl)piperazin-1-yl]quinoline-3-carboxylate

ethyl 8-methoxy-4-(4-thiophen-2-ylpiperazin-1-yl)quinoline-3-carboxylate

ethyl 8-methoxy-4-[4-[2-(trifluoromethoxy)phenyl]piperazin-1-yl]quinoline-3-carboxylate