Brief Information of the Compound and Protein
Compound Name
6-fluoro-4-[4-(2-fluorophenyl)piperazin-1-yl]-8-(oxolan-3-yloxy)quinoline-3-carbonitrile
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Canonical SMILES
Fc1cc(OC2CCOC2)c2ncc(C#N)c(N3CCN(CC3)c3ccccc3F)c2c1
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Compound Formula C24H22F2N4O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 7
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P35400
Gene Name
GRM7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 510 nM
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