General Information of the Compound
| Compound ID |
CP0416254
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| Compound Name |
7-(4-fluorophenyl)-2-[[2-(trifluoromethyl)pyridin-4-yl]oxymethyl]pyrazolo[1,5-a]pyrimidine-5-carboxamide
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| Structure |
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| Formula |
C20H13F4N5O2
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| Molecular Weight |
431.349
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| Canonical SMILES |
NC(=O)c1cc(-c2ccc(F)cc2)n2nc(COc3ccnc(c3)C(F)(F)F)cc2n1
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| InChI |
InChI=1S/C20H13F4N5O2/c21-12-3-1-11(2-4-12)16-9-15(19(25)30)27-18-7-13(28-29(16)18)10-31-14-5-6-26-17(8-14)20(22,23)24/h1-9H,10H2,(H2,25,30)
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| InChIKey |
WZTHJWNYBIKZNF-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01994, Metabotropic glutamate receptor 1
Protein ID: PT02446, Metabotropic glutamate receptor 4
Protein ID: PT00854, Metabotropic glutamate receptor 5
Protein ID: PT02744, Metabotropic glutamate receptor 6
Protein ID: PT03457, Metabotropic glutamate receptor 7
Protein ID: PT04980, Metabotropic glutamate receptor 8