Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03073 , Solute carrier family 22 member 12
Gene Name SLC22A12
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q96S37
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT03073
 
Compound ID Compound Name Compound Formula
CP0541128
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-pyridin-3-ylmethanesulfonamide
   Show/Hide
C19H15Br2N5O2S2
 1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CP0102676
1-(6-bromoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C14H12BrNO2S
 1
1
IC50 = 33.7 nM
   TI
   LI
   LO
   TS
CP0517742
1-[2-(4-cyanophenyl)phenyl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C18H15NO2S
 1
1
IC50 < 50 nM
   TI
   LI
   LO
   TS
CP0385475
1-[6-(trifluoromethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C15H12F3NO2S
 1
1
IC50 = 61.2 nM
   TI
   LI
   LO
   TS
CP0547970
sodium;2-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetate
   Show/Hide
C15H10Br2N3NaO2S
 1
1
IC50 = 94 nM
   TI
   LI
   LO
   TS
CP0429844
1-[6-[2-(trifluoromethyl)phenyl]quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C21H16F3NO2S
 1
1
IC50 = 115.3 nM
   TI
   LI
   LO
   TS
CP0375457
1-(7-bromoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C14H12BrNO2S
 1
1
IC50 = 129.8 nM
   TI
   LI
   LO
   TS
CP0491662
US8889724, EG
   Show/Hide
C18H20N4O
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0463051
1-[6-(4-fluorophenyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C20H16FNO2S
 1
1
IC50 = 158.8 nM
   TI
   LI
   LO
   TS
CP0546617
sodium;2-[3-(4-cyanonaphthalen-1-yl)pyridin-4-yl]sulfanyl-2-methylpropanoate
   Show/Hide
C20H15N2NaO2S
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0463105
1-[6-(methoxymethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C16H17NO3S
 1
1
IC50 = 197.8 nM
   TI
   LI
   LO
   TS
CP0541063
1-[6-(2-methoxyethoxy)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C17H19NO4S
 1
1
IC50 = 206.9 nM
   TI
   LI
   LO
   TS
CP0556249
US8889724, EC
   Show/Hide
C17H18N4O
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0546619
sodium;2-[[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylmethyl]benzoate
   Show/Hide
C24H16N3NaO2S
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0491664
US8889724, ED
   Show/Hide
C18H20N4O2
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0575161
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2-bromopyridin-3-yl)methanesulfonamide
   Show/Hide
C19H14Br3N5O2S2
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0538447
1-(6-bromoquinolin-4-yl)sulfanylcyclopentane-1-carboxylic acid
   Show/Hide
C15H14BrNO2S
 1
1
IC50 = 324.3 nM
   TI
   LI
   LO
   TS
CP0420503
1-[6-(2-fluorophenyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C20H16FNO2S
 1
1
IC50 = 333.4 nM
   TI
   LI
   LO
   TS
CP0434753
1-(6-methoxyquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C15H15NO3S
 1
1
IC50 = 342.8 nM
   TI
   LI
   LO
   TS
CP0538448
1-(6-methylquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C15H15NO2S
 1
1
IC50 = 343.2 nM
   TI
   LI
   LO
   TS
CP0385474
1-(6-bromoquinolin-4-yl)sulfanylcyclopropane-1-carboxylic acid
   Show/Hide
C13H10BrNO2S
 1
1
IC50 = 352.3 nM
   TI
   LI
   LO
   TS
CP0385473
1-[6-[3-(trifluoromethyl)phenyl]quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C21H16F3NO2S
 1
1
IC50 = 358.7 nM
   TI
   LI
   LO
   TS
CP0417801
1-(6-cyanoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C15H12N2O2S
 1
1
IC50 = 398.8 nM
   TI
   LI
   LO
   TS
CP0456496
1-quinolin-4-ylsulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C14H13NO2S
 1
1
IC50 = 448 nM
   TI
   LI
   LO
   TS
CP0546618
sodium;4-[[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylmethyl]-3-methoxybenzoate
   Show/Hide
C26H20N3NaO3S
 1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CP0538449
1-(6-fluoroquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C14H12FNO2S
 1
1
IC50 = 557.6 nM
   TI
   LI
   LO
   TS
CP0559979
2-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-hydroxyacetamide
   Show/Hide
C15H12Br2N4O2S
 1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS
CP0472125
1-(6-cyclopropylquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C17H17NO2S
 1
1
IC50 = 659.2 nM
   TI
   LI
   LO
   TS
CP0406890
1-[6-(cyanomethoxy)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C16H14N2O3S
 1
1
IC50 = 680.2 nM
   TI
   LI
   LO
   TS
CP0491661
US8889724, EF
   Show/Hide
C18H20N4O
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0041383
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
   Show/Hide
C17H12Br2O3
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0375456
1-(4-cyanonaphthalen-1-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C16H13NO2S
 1
1
IC50 = 926.4 nM
   TI
   LI
   LO
   TS
CP0527621
US8889724, EB
   Show/Hide
C16H16N4O
 1
1
IC50 = 930 nM
   TI
   LI
   LO
   TS
CP0559825
1-[6-(3-fluorophenyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C20H16FNO2S
 1
1
IC50 = 1189 nM
   TI
   LI
   LO
   TS
CP0571249
sodium;4-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylbutanoate
   Show/Hide
C20H15N2NaO3S
 1
1
IC50 = 1230 nM
   TI
   LI
   LO
   TS
CP0538106
1-[6-(hydroxymethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C15H15NO3S
 1
1
IC50 = 1257 nM
   TI
   LI
   LO
   TS
CP0568250
2-[1-[(4-bromonaphthalen-1-yl)methyl]imidazo[4,5-b]pyridin-2-yl]sulfanyl-2-methylpropanoic acid
   Show/Hide
C21H18BrN3O2S
 1
1
IC50 = 1360 nM
   TI
   LI
   LO
   TS
CP0549091
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(6-fluoropyridin-3-yl)methanesulfonamide
   Show/Hide
C19H14Br2FN5O2S2
 1
1
IC50 = 1550 nM
   TI
   LI
   LO
   TS
CP0552688
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2,6-dichloropyridin-3-yl)methanesulfonamide
   Show/Hide
C19H13Br2Cl2N5O2S2
 1
1
IC50 = 1660 nM
   TI
   LI
   LO
   TS
CP0570258
sodium;4-[[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylmethyl]-3-methoxybenzoate
   Show/Hide
C25H18N3NaO3S
 1
1
IC50 = 1660 nM
   TI
   LI
   LO
   TS
CP0472133
1-[6-[4-(trifluoromethyl)phenyl]quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C21H16F3NO2S
 1
1
IC50 = 1753 nM
   TI
   LI
   LO
   TS
CP0385626
1-(6-aminoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C14H14N2O2S
 1
1
IC50 = 1787 nM
   TI
   LI
   LO
   TS
CP0486629
1-[6-(2-hydroxyethoxy)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C16H17NO4S
 1
1
IC50 = 1886 nM
   TI
   LI
   LO
   TS
CP0375461
1-(1,6-naphthyridin-4-ylsulfanyl)cyclobutane-1-carboxylic acid
   Show/Hide
C13H12N2O2S
 1
1
IC50 = 1932 nM
   TI
   LI
   LO
   TS
CP0547968
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(6-chloropyridin-3-yl)methanesulfonamide
   Show/Hide
C19H14Br2ClN5O2S2
 1
1
IC50 = 1940 nM
   TI
   LI
   LO
   TS
CP0567735
sodium;3-[[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylmethyl]benzoate
   Show/Hide
C24H16N3NaO2S
 1
1
IC50 = 1960 nM
   TI
   LI
   LO
   TS
CP0555223
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(6-bromopyridin-3-yl)methanesulfonamide
   Show/Hide
C19H14Br3N5O2S2
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0578825
sodium;5-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylpentanoate
   Show/Hide
C21H18N3NaO2S
 1
1
IC50 = 2280 nM
   TI
   LI
   LO
   TS
CP0570427
3-[1-[(4-cyclopropylnaphthalen-1-yl)methyl]imidazo[4,5-b]pyridin-2-yl]sulfanylpropanoic acid
   Show/Hide
C23H21N3O2S
 1
1
IC50 = 2490 nM
   TI
   LI
   LO
   TS
CP0580203
sodium;4-[[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylmethyl]benzoate
   Show/Hide
C24H16N3NaO2S
 1
1
IC50 = 2550 nM
   TI
   LI
   LO
   TS
CP0578050
2-[1-[(4-bromonaphthalen-1-yl)methyl]imidazo[4,5-c]pyridin-2-yl]sulfanyl-2-methylpropanoic acid
   Show/Hide
C21H18BrN3O2S
 1
1
IC50 = 2570 nM
   TI
   LI
   LO
   TS
CP0578824
sodium;4-[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylbutanoate
   Show/Hide
C21H18N3NaO2S
 1
1
IC50 = 2580 nM
   TI
   LI
   LO
   TS
CP0375459
1-[6-(2-cyanoethyl)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
   Show/Hide
C17H16N2O2S
 1
1
IC50 = 2757 nM
   TI
   LI
   LO
   TS
CP0578907
sodium;4-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylbutanoate
   Show/Hide
C20H16N3NaO2S
 1
1
IC50 = 2780 nM
   TI
   LI
   LO
   TS
CP0537985
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2,5-dichloropyridin-3-yl)methanesulfonamide
   Show/Hide
C19H13Br2Cl2N5O2S2
 1
1
IC50 = 2790 nM
   TI
   LI
   LO
   TS
CP0578051
2-[1-(4-cyclopropylnaphthalen-1-yl)imidazo[4,5-b]pyridin-2-yl]oxy-2-methylpropanoic acid
   Show/Hide
C23H21N3O3
 1
1
IC50 = 3060 nM
   TI
   LI
   LO
   TS
CP0548163
sodium;5-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanylmethyl]-1,2,3-triaza-4-azanidacyclopenta-2,5-diene
   Show/Hide
C15H10Br2N7NaS
 1
1
IC50 = 3240 nM
   TI
   LI
   LO
   TS
CP0578826
sodium;2-[2-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanyl-6-nitrophenyl]acetate
   Show/Hide
C24H15N4NaO4S
 1
1
IC50 = 3440 nM
   TI
   LI
   LO
   TS
CP0010999
4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
   Show/Hide
C18H12Cl2FN5O3S2
 1
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0568249
2-[1-[(4-cyclopropylnaphthalen-1-yl)methyl]imidazo[4,5-c]pyridin-2-yl]sulfanylacetic acid
   Show/Hide
C22H19N3O2S
 1
1
IC50 = 3550 nM
   TI
   LI
   LO
   TS
CP0580201
sodium;3-[[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylmethyl]benzoate
   Show/Hide
C25H18N3NaO2S
 1
1
IC50 = 3570 nM
   TI
   LI
   LO
   TS
CP0577433
sodium;5-[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylpentanoate
   Show/Hide
C22H20N3NaO2S
 1
1
IC50 = 3580 nM
   TI
   LI
   LO
   TS
CP0579517
1-[1-(4-cyclopropylnaphthalen-1-yl)imidazo[4,5-b]pyridin-2-yl]oxycyclobutane-1-carboxylic acid
   Show/Hide
C24H21N3O3
 1
1
IC50 = 3670 nM
   TI
   LI
   LO
   TS
CP0579209
2-[1-(4-cyclopropylnaphthalen-1-yl)imidazo[4,5-b]pyridin-2-yl]oxypropanoic acid
   Show/Hide
C22H19N3O3
 1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
CP0577111
sodium;6-[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylhexanoate
   Show/Hide
C23H22N3NaO2S
 1
1
IC50 = 3760 nM
   TI
   LI
   LO
   TS
CP0574280
sodium;7-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylheptanoate
   Show/Hide
C23H21N2NaO3S
 1
1
IC50 = 3780 nM
   TI
   LI
   LO
   TS
CP0432064
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxypyridin-3-yl)methanesulfonamide
   Show/Hide
C20H17Br2N5O3S2
 1
1
IC50 = 4050 nM
   TI
   LI
   LO
   TS
CP0576347
sodium;2-[5-bromo-2-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylphenyl]acetate
   Show/Hide
C24H15BrN3NaO2S
 1
1
IC50 = 4120 nM
   TI
   LI
   LO
   TS
CP0573739
sodium;5-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylpentanoate
   Show/Hide
C21H17N2NaO3S
 1
1
IC50 = 4220 nM
   TI
   LI
   LO
   TS
CP0571299
sodium;6-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylhexanoate
   Show/Hide
C22H20N3NaO2S
 1
1
IC50 = 4240 nM
   TI
   LI
   LO
   TS
CP0579630
sodium;2-[2-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanyl-5-methoxyphenyl]acetate
   Show/Hide
C25H18N3NaO3S
 1
1
IC50 = 4250 nM
   TI
   LI
   LO
   TS
CP0573738
sodium;2-[[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylmethyl]benzoate
   Show/Hide
C25H18N3NaO2S
 1
1
IC50 = 4440 nM
   TI
   LI
   LO
   TS
CP0580202
sodium;2-[4-[[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylmethyl]phenyl]benzoate
   Show/Hide
C31H22N3NaO2S
 1
1
IC50 = 4570 nM
   TI
   LI
   LO
   TS
CP0578823
sodium;7-[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylheptanoate
   Show/Hide
C24H24N3NaO2S
 1
1
IC50 = 4640 nM
   TI
   LI
   LO
   TS
CP0576346
sodium;2-[4-[[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylmethyl]phenyl]benzoate
   Show/Hide
C30H20N3NaO2S
 1
1
IC50 = 4680 nM
   TI
   LI
   LO
   TS
CP0573740
sodium;6-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylhexanoate
   Show/Hide
C22H19N2NaO3S
 1
1
IC50 = 4740 nM
   TI
   LI
   LO
   TS
CP0579966
3-[1-(4-cyclopropylnaphthalen-1-yl)imidazo[4,5-b]pyridin-2-yl]oxypropanoic acid
   Show/Hide
C22H19N3O3
 1
1
IC50 = 4940 nM
   TI
   LI
   LO
   TS
CP0569911
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2-chloropyridin-3-yl)methanesulfonamide
   Show/Hide
C19H14Br2ClN5O2S2
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0578892
sodium;2-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanyl-2-methylpropanoate
   Show/Hide
C20H15N2NaO3S
 1
1
IC50 = 5210 nM
   TI
   LI
   LO
   TS
CP0574304
sodium;2-[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanyl-2-methylpropanoate
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C21H18N3NaO2S
 1
1
IC50 = 5360 nM
   TI
   LI
   LO
   TS
CP0549191
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2,6-dibromopyridin-3-yl)methanesulfonamide
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C19H13Br4N5O2S2
 1
1
IC50 = 5410 nM
   TI
   LI
   LO
   TS
CP0674431
LESINURAD
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C17H14BrN3O2S
 2
1
IC50 = 5540 nM
   TI
   LI
   LO
   TS
2
IC50 = 7200 nM
   TI
   LI
   LO
   TS
CP0571298
sodium;7-[3-[(4-cyanonaphthalen-1-yl)amino]pyridin-4-yl]sulfanylheptanoate
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C23H22N3NaO2S
 1
1
IC50 = 5750 nM
   TI
   LI
   LO
   TS
CP0550521
sodium;4-[[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylmethyl]benzoate
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C25H18N3NaO2S
 1
1
IC50 = 6250 nM
   TI
   LI
   LO
   TS
CP0558553
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-[5-(trifluoromethyl)pyridin-3-yl]methanesulfonamide
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C20H14Br2F3N5O2S2
 1
1
IC50 = 6380 nM
   TI
   LI
   LO
   TS
CP0546615
sodium;3-[[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylmethyl]benzoate
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C24H15N2NaO3S
 1
1
IC50 = 6580 nM
   TI
   LI
   LO
   TS
CP0574293
sodium;2-[[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylmethyl]benzoate
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C24H15N2NaO3S
 1
1
IC50 = 6860 nM
   TI
   LI
   LO
   TS
CP0546614
sodium;2-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylacetate
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C18H11N2NaO3S
 1
1
IC50 = 6970 nM
   TI
   LI
   LO
   TS
CP0574294
sodium;2-[5-bromo-2-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylphenyl]acetate
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C24H14BrN2NaO3S
 1
1
IC50 = 8050 nM
   TI
   LI
   LO
   TS
CP0385482
1-quinazolin-4-ylsulfanylcyclobutane-1-carboxylic acid
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C13H12N2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0403505
1-(6-hydroxyquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
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C14H13NO3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0403506
1-[(3-oxo-4H-1,4-benzoxazin-5-yl)sulfanyl]cyclobutane-1-carboxylic acid
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C13H13NO4S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0403507
1-quinazolin-4-yloxycyclobutane-1-carboxylic acid
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C13H12N2O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0406891
1-(1,6-naphthyridin-5-ylsulfanyl)cyclobutane-1-carboxylic acid
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C13H12N2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0417799
1-[6-[2-(methylamino)-2-oxoethoxy]quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
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C17H18N2O4S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0463052
1-[6-(cyclopropanecarbonylamino)quinolin-4-yl]sulfanylcyclobutane-1-carboxylic acid
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C18H18N2O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0538441
1-(1,5-naphthyridin-4-ylsulfanyl)cyclobutane-1-carboxylic acid
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C13H12N2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0564207
1-(6-acetamidoquinolin-4-yl)sulfanylcyclobutane-1-carboxylic acid
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C16H16N2O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0554602
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-[6-(trifluoromethyl)pyridin-3-yl]methanesulfonamide
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C20H14Br2F3N5O2S2
 1
1
IC50 = 10210 nM
   TI
   LI
   LO
   TS
CP0568801
sodium;4-[[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylmethyl]benzoate
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C24H15N2NaO3S
 1
1
IC50 = 10250 nM
   TI
   LI
   LO
   TS
CP0577104
sodium;2-[2-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanyl-6-nitrophenyl]acetate
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C24H14N3NaO5S
 1
1
IC50 = 10450 nM
   TI
   LI
   LO
   TS
CP0533504
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-iodopyridin-3-yl)methanesulfonamide
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C19H14Br2IN5O2S2
 1
1
IC50 = 10570 nM
   TI
   LI
   LO
   TS
CP0546616
sodium;2-[2-[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanyl-5-methoxyphenyl]acetate
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C25H17N2NaO4S
 1
1
IC50 = 14180 nM
   TI
   LI
   LO
   TS
CP0554603
sodium;[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanylmethanesulfonate
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C14H10Br2N3NaO3S2
 1
1
IC50 = 14380 nM
   TI
   LI
   LO
   TS
CP0576348
sodium;2-[4-[[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylmethyl]phenyl]benzoate
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C30H19N2NaO3S
 1
1
IC50 = 15110 nM
   TI
   LI
   LO
   TS
CP0432021
1-[[5-bromo-4-[(4-bromonaphthalen-1-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-phenylmethanesulfonamide
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C20H16Br2N4O2S2
 1
1
IC50 = 15780 nM
   TI
   LI
   LO
   TS
CP0575659
sodium;4-[[3-(4-cyanonaphthalen-1-yl)oxypyridin-4-yl]sulfanylmethyl]-3-methoxybenzoate
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C25H17N2NaO4S
 1
1
IC50 = 16350 nM
   TI
   LI
   LO
   TS