General Information of the Compound
Compound ID
CP0546618
Compound Name
sodium;4-[[3-[(4-cyanonaphthalen-1-yl)-methylamino]pyridin-4-yl]sulfanylmethyl]-3-methoxybenzoate
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Structure
Formula
C26H20N3NaO3S
Molecular Weight
477.521
Canonical SMILES
[Na+].COc1cc(ccc1CSc1ccncc1N(C)c1ccc(C#N)c2ccccc12)C([O-])=O
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InChI
InChI=1S/C26H21N3O3S.Na/c1-29(22-10-9-18(14-27)20-5-3-4-6-21(20)22)23-15-28-12-11-25(23)33-16-19-8-7-17(26(30)31)13-24(19)32-2;/h3-13,15H,16H2,1-2H3,(H,30,31);/q;+1/p-1
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InChIKey
GNXUKKVJHAQDQR-UHFFFAOYSA-M
Physicochemical Property
logP
1.54278
Rotatable Bonds
7
Heavy Atom Count
34
Polar Areas
89.28
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168281558
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03073, Solute carrier family 22 member 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 460 nM
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   LI
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   TS
Protein ID: PT04064, Solute carrier family 22 member 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 25540 nM
   TI
   LI
   LO
   TS