Brief Information of the Compound and Protein
Compound Name
LESINURAD
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PubChem ID
CID: 53465279
Canonical SMILES
O=C(O)CSc1nnc(Br)n1-c1ccc(C2CC2)c2ccccc12
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Compound Formula C17H14BrN3O2S
Compound Structure
Protein Name
Solute carrier family 22 member 12
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC22 family of organic cation and anion transporters
Uniprot ID
Q96S37
Gene Name
SLC22A12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 13210 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 5540 nM
   TI
   LI
   LO
   TS
2
IC50 = 7200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3700 nM
2 IC50 = 6700 nM
3 IC50 = 7300 nM