8-Bromotryptanthrin

2,8-difluoroindolo[2,1-b]quinazoline-6,12-dione

2-[(dimethylamino)methyl]-8-fluoroindolo[2,1-b]quinazoline-6,12-dione

8-nitroindolo[2,1-b]quinazoline-6,12-dione

8-fluoranylindolo[2,1-b]quinazoline-6,12-dione

tert-butyl 4-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]piperazine-1-carboxylate

8-fluoro-2-(morpholin-4-ylmethyl)indolo[2,1-b]quinazoline-6,12-dione

8-fluoro-2-[(4-methylpiperazin-1-yl)methyl]indolo[2,1-b]quinazoline-6,12-dione

8-fluoro-2-(piperazin-1-ylmethyl)indolo[2,1-b]quinazoline-6,12-dione

indolo[2,1-b]quinazoline-6,12-dione

2-[(4-methylpiperazin-1-yl)methyl]indolo[2,1-b]quinazoline-6,12-dione

8-methylindolo[2,1-b]quinazoline-6,12-dione

7-chloroindolo[2,1-b]quinazoline-6,12-dione

2-fluoroindolo[2,1-b]quinazoline-6,12-dione

US10034864, Example 1

8-fluoro-2-(4-methylpiperazin-1-yl)indolo[2,1-b]quinazoline-6,12-dione

2-(dimethylamino)-8-fluoroindolo[2,1-b]quinazoline-6,12-dione

8-fluoro-2-piperazin-1-ylindolo[2,1-b]quinazoline-6,12-dione

1-(chloromethyl)-6,6-dimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione

US10155972, Compound LM10

2-(4-methylpiperazin-1-yl)indolo[2,1-b]quinazoline-6,12-dione

2-morpholin-4-ylindolo[2,1-b]quinazoline-6,12-dione

1-(fluoromethyl)-6,6-dimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione

9-chloroindolo[2,1-b]quinazoline-6,12-dione

(6,6-dimethyl-7,10,11-trioxo-8,9-dihydronaphtho[1,2-g][1]benzofuran-1-yl)methyl acetate

(7S)-7-hydroxy-1-(hydroxymethyl)-6,6-dimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione

1-(hydroxymethyl)-6,6-dimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione

(6,6-dimethyl-7,10,11-trioxonaphtho[1,2-g][1]benzofuran-1-yl)methyl acetate

[(7S)-1-(hydroxymethyl)-6,6-dimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-7-yl] acetate

[(7S)-7-hydroxy-6,6-dimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-1-yl]methyl acetate

N-(4-chlorophenyl)-2-[4-(6-chloroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

[(7S)-1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-7-yl] acetate

1-(hydroxymethyl)-6,6-dimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-7,10,11-trione

8-fluoro-2-piperidin-1-ylindolo[2,1-b]quinazoline-6,12-dione

CHEMBL4161733

N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)-3,3-dimethylpiperidin-1-yl]-2-oxoacetamide

N-(4-cyanophenyl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-[4-(difluoromethyl)phenyl]-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-(5-chloropyridin-2-yl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-(4-chloro-2-fluorophenyl)-2-[4-(6-fluoroquinolin-4-yl)azepan-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[4-(6-cyanoquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[3,3-difluoro-4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-(5-chloropyridin-2-yl)-2-oxo-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]acetamide

N-(4-chloro-2-fluorophenyl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[2-methyl-6-(trifluoromethyl)spiro[1H-isoindole-3,4'-cyclohexane]-1'-yl]propanamide

(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-furo[2,3-b]pyridine-3,4'-cyclohexane]-1'-yl]propanamide

PRZEWAQUINONE A

(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide

(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide

9-bromo-1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione

N-(4-chlorophenyl)-4-hydroxy-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]butanamide

2-[4-(6-fluoroquinolin-4-yl)piperidin-1-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide

3-Hydroxytanshinone

N,N-diethyl-6,6-dimethyl-7,10,11-trioxonaphtho[1,2-g][1]benzofuran-1-carboxamide

8-hydroxy-1,6,6-trimethylnaphtho[1,2-g][1]benzofuran-9,10,11-trione

6,6-dimethyl-7,10,11-trioxonaphtho[1,2-g][1]benzofuran-1-carboxylic acid

[(7S)-1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-7-yl] methanesulfonate

1,6,6-trimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-7,10,11-trione

8-hydroxy-1,6,6-trimethyl-7,8-dihydronaphtho[1,2-g][1]benzofuran-9,10,11-trione

1,6,6-trimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione

(2R)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide

(2R)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]propanamide

(2S)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]butanamide

N-(4-chlorophenyl)-2-[7-(trifluoromethyl)spiro[2,3-dihydrochromene-4,4'-piperidine]-1'-yl]butanamide

N-(4-chlorophenyl)-2-[(3R,4R)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[(3S,4S)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide

(2R)-N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]butanamide

N-(4-chlorophenyl)-3-cyclopropyl-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]propanamide

N-(4-chloro-2-fluorophenyl)-2-[4-(6-fluoroquinolin-4-yl)-2,3,6,7-tetrahydroazepin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[(3S,4R)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide

(2S)-N-(4-chlorophenyl)-2-[5-(trifluoromethyl)spiro[2H-furo[2,3-b]pyridine-3,4'-cyclohexane]-1'-yl]propanamide

N-(4-chlorophenyl)-2-oxo-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]acetamide

N-(5-chloropyridin-2-yl)-2-[4-[3-chloro-2-(trifluoromethyl)pyridin-4-yl]piperidin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]acetamide

(2S)-N-(5-chloropyridin-2-yl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-cyclohexane]-1'-yl]butanamide

N-(4-chlorophenyl)-2-[6-(difluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]propanamide

N-(4-chlorophenyl)-2-oxo-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-azepane]-1'-yl]acetamide

N-(4-chlorophenyl)-2-[(3R,4S)-4-(6-fluoroquinolin-4-yl)-3-hydroxypiperidin-1-yl]-2-oxoacetamide

N-(4-chlorophenyl)-2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpropanamide

N-(4-chlorophenyl)-2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylacetamide

N-(4-chlorophenyl)-2-methyl-2-[6-(trifluoromethyl)spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]propanamide